Clinical trials: Environmental Enteric Dysfunction, open to volunteers
Environmental Enteric Dysfunction (EED), Malnutrition
The Maternal EED Study
Undernutrition among women of reproductive age is more common in South Asia than in any other region. In South Asia, the prevalence of maternal undernutrition varies between 10 and 40%.
- Conditions
- Environmental Enteric Dysfunction (EED), Malnutrition, Women of Reproductive Age, Gut Microbiota
- Trial name
- NCT05862363
- Testing
- Microbiota-directed balanced energy protein (MD-BEP), Ready-to-use supplementary food-balanced energy protein (RUSF-BEP), Esophagogastroduodenoscopy (EGD)
- Where
- Bangladesh
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Environmental Enteric Dysfunction
OCT Guided Trans Nasal Imaging of the Small Intestine in Adults
The investigators are seeking healthy adult participants 18-60 years and healthy pregnant women in their 2nd trimester of pregnancy for a research study to assess a new imaging device.
- Trial name
- NCT04984447
- Testing
- TNIB Catheter
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Urinary Tract Infections, Malnutrition
Effect of Hygiene and Menstrual Hygiene Interventions on Learning and Psychosocial Wellbeing in Madagascar
A previous study in schools in rural Madagascar found that a bundle of hygiene-focused interventions substantially improved girls' learning outcomes.
- Conditions
- Urinary Tract Infections, Malnutrition, Inflammation, Stress
- Trial name
- KILONGA2 (NCT07702916)
- Testing
- Peer leadership/sensitization + sanitary pads, School infrastructure
- Where
- Madagascar
- Volunteers
- 3,080 people, healthy volunteers welcome
- Sponsor
- University of California Santa Cruz
Malnutrition Pregnancy, Malnutrition in Children
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories
Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it.
- Conditions
- Malnutrition Pregnancy, Malnutrition in Children, Malnutrition (Calorie), Environmental Enteric Dysfunction
- Trial name
- UZBCS-2 (NCT07195006)
- Testing
- Malnutrition in pregnancy as exposure, Poor WASH living conditions as exposure
- Where
- Zimbabwe
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Amino Acid, Stunting, Environmental Enteric Dysfunction
The Efficacy of Amino Acid Supplementation in Treating Environmental Enteric Dysfunction Among Children At Risk of Malnutrition
A randomised controlled open label clinical trial to determine whether addition of indispensable amino acids (IAA) to standard complementary food will reduce occurrence of Environmental Enteric Dysfunction (EED) compared with…
- Trial name
- NCT06617130
- Testing
- Corn soy bean blended flour porridge plus indispensable amino acid
- Where
- Malawi
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kamuzu University of Health Sciences
Environmental Enteric Dysfunction
Capsule Endomicroscopy for Visualization of the Small Intestine in EED Population in Pakistan
This pilot study will test the feasibility and tolerability of the tethered OCT capsule and Trans Nasal Endomicroscopy probe and accessory devices for imaging the small intestine in subjects with EED and a matched non-EED cohort.
- Trial name
- NCT04275167
- Testing
- Tethered Capsule Endomicroscope/Trans Nasal Endomicroscope
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital