Clinical trials: Environmental Health
Breast Cancer Prevention
MELIORA Virtual Coach Intervention for Breast Cancer Prevention
Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide, with early-onset cases increasing due to genetic and lifestyle factors.
- Trial name
- MELIORA (NCT07200427)
- Testing
- MELIORA Virtual Coach Intervention, Control (generic advice)
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Post Traumatic Stress Disorder
Effect of Exercise on Post-traumatic Growth Among Health Care Providers With Post-traumatic Stress
The purpose of designing this randomized control trial is to observe the effect of nature-based walk on post-traumatic growth and Psychophysiological alterations associated with it, in traumatic stress among health care providers…
- Trial name
- NCT04592770
- Testing
- Nature based walk therapy, Sit in nature
- Where
- Pakistan
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Asthma, Pneumonia
PECO Air Purification in Hospital Rooms to Improve Health Outcomes for Pediatric Respiratory Distress
This study will investigate the efficacy of a novel air purification technology, Photo Electrochemical Oxidation (PECO), has on pediatric patients hospitalized for respiratory distress.
- Conditions
- Asthma, Pneumonia, Respiratory Distress Syndrome
- Trial name
- NCT03647397
- Testing
- Photo Electrochemical Oxidation (PECO) for Air Purification
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Molekule
Obesity, Physical Inactivity
Changing Healthy Outcomes In Clinic Environments
This study will compare three methods of counseling to determine which is most effective at motivating participants to adopt healthy lifestyle habits.
- Conditions
- Obesity, Physical Inactivity, Diabetes
- Trial name
- CHOICE (NCT00674518)
- Testing
- One on one counseling, Group/team - based health education, PACE physician counseling
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Oregon Health and Science University
Cardiometabolic Syndrome
Effect of a Vegan Diet Versus a Mediterranean Diet. Assessing Health Outcomes
This study aimed to evaluate the effect of a vegan diet (supplemented with vitamin B12) and an mediterranean diet on performance, cardiorespiratory fitness, metabolic health, immune status, and environmental impact in healthy…
- Trial name
- OMNIVEG (NCT06008886)
- Testing
- Vegan diet, Mediterranean diet
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Parkinson's Disease
Shanghai Parkinson's Study
Background: Parkinson disease (PD) is the second most prevalent neurodegenerative disease, affecting more than 1 percent of the elderly population in the United States and other Western countries.
- Trial name
- NCT00999388
- Where
- 2 sites in China
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Smoking Cessation
Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments
The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation across rural primary care settings.
- Trial name
- INSPIRE (NCT05764759)
- Testing
- Smoking cessation e-visit, Treatment as usual
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Melanoma
The Impact of a Prevention Program on Sun Risks in Primary School in Tropical French Region
Sun exposure during childhood can cause the development of skin cancer in later years, in particular melanoma, which is the most lethal.The worldwide incidence of melanoma is on the rise, with nearly 290,000 new cases diagnosed…
- Trial name
- PRESOLRE (NCT05367180)
- Testing
- MISOLRE prevention program on sun risks, "Vivre avec le Soleil" prevention program on sun risks, Sun protection equipment
- Where
- Reunion
- Volunteers
- 1,452 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Spontaneous Abortion, Fetal Death
Environmental Factors and Embryonic Development Project
The Environmental Factors and Embryonic Development Project was set up to investigate environmental exposures and behavioral factors responsible for embryonic dysplasia and gestational complications in pregnant women.
- Conditions
- Spontaneous Abortion, Fetal Death, Stillbirth, Birth Defects
- Trial name
- EFED (NCT04182503)
- Testing
- No intervention
- Where
- 19 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Pollution; Exposure
Scalability of a Home Health Navigator Program to Reduce Arsenic, Nitrate, and Lead in Private Well Water
Approximately 34 million Americans rely on private wells to supply their drinking water. Private wells are excluded from the Safe Drinking Water Act.
- Trial name
- NCT05395663
- Testing
- Community health worker
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Malnutrition Pregnancy, Malnutrition in Children
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories
Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it.
- Conditions
- Malnutrition Pregnancy, Malnutrition in Children, Malnutrition (Calorie), Environmental Enteric Dysfunction
- Trial name
- UZBCS-2 (NCT07195006)
- Testing
- Malnutrition in pregnancy as exposure, Poor WASH living conditions as exposure
- Where
- Zimbabwe
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Mental Health, Child Wellbeing
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes.
- Conditions
- Mental Health, Child Wellbeing, Infant Health, Child Health
- Trial name
- GenV (NCT05394363)
- Where
- Australia
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Bronchiolitis, Pneumonia
A Study of Tobacco Smoke and Children With Respiratory Illnesses
This study aims to assess the feasibility of using an intervention for environmental smoke exposure in children that uses cotinine testing results with written materials and telephone counseling for a potential future study of…
- Conditions
- Bronchiolitis, Pneumonia, Reactive Airway Disease, Asthma
- Trial name
- NCT03062709
- Testing
- Breathe Easy Coalition written materials, Maine Tobacco Helpline, Urine cotinine testing
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- MaineHealth
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Quality of Life, Psychological Distress
Impact of a Climate-Adapted Self-Management Intervention for Hypertension: A Randomized Controlled Trial Examining Psychosocial and Environmental Determinants
This study aims to evaluate the effectiveness of a Climate-Adapted Self-Management Intervention in improving the quality of life among adults with hypertension.
- Conditions
- Quality of Life, Psychological Distress, Climate Change Anxiety, Health Behaviors
- Trial name
- NCT07720752
- Testing
- Climate-Adapted Self-Management Intervention
- Where
- 3 sites in Pakistan
- Volunteers
- 44 people
- Sponsor
- Fatima Jinnah Women University
Stress Disorder, Burnout, Professional
Use of Wearable Devices to Assess the Impact of Stress in Workers' Life Quality
Introduction: Work stress has become more and more important in the last years as it affects both health and productivity of workers.
- Conditions
- Stress Disorder, Burnout, Professional, Sleep Disorder, Quality of Life
- Trial name
- SQoF-WEAR (NCT04584021)
- Testing
- Xiaomi MiBand3, Socio-demographic questionnaire, EuroQol-5D-5L
- Where
- Spain
- Volunteers
- 11 people
- Sponsor
- Universidade da Coruña