Clinical trials: Eosinophilic Gastrointestinal Disease
Eosinophilic Esophagitis
Prospective Multicenter Nationwide Registry of Children With Eosinophilic Esophagitis
1. Registry of demographic, clinical, endoscopic and histological data at baseline. 2. Registry of patients treated with PPI: Clinical, endoscopic and histological response at 8-12 weeks of induction treatment Clinical…
- Trial name
- RENESE (NCT03858426)
- Testing
- no intervention
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Sociedad Espanola de Gastroenterologia, Hepatologia y Nutricion Pediatrica
Eosinophilic Esophagitis (EoE)
A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis
This study is researching an experimental drug called dupilumab (called "study drug"). The study is focused on children with active eosinophilic esophagitis (EoE; an inflammatory disease of the esophagus) which impacts feeding…
- Trial name
- EoE-TOTs (NCT07112378)
- Testing
- dupilumab
- Where
- 13 sites in United States
- Volunteers
- 20 people
- Sponsor
- Regeneron Pharmaceuticals
Eosinophilic Esophagitis
Validation in French of a Quality of Life Questionnaire for Patients With Eosinophilic Esophagitis in Pediatrics
Eosinophilic esophagitis is a chronic condition of the esophagus. The symptoms of eosinophilic esophagitis can affect the quality of life of affected children.
- Trial name
- ValidEoE (NCT05900011)
- Testing
- Quality of life questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Lenval
Eosinophilic Duodenitis, Eosinophilic Gastroenteritis
A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis
This is a Phase 3, multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of lirentelimab (AK002) given monthly for 6 doses in adult patients with active eosinophilic duodenitis.
- Trial name
- EoDyssey (NCT04856891)
- Testing
- AK002
- Where
- 39 sites in United States
- Volunteers
- 94 people
- Sponsor
- Allakos Inc.
Eosinophilic Esophagitis
Esophageal Absorption in EoE
To determine how the esophagus in active and inactive stages of eosinophilic esophagitis tranmit fluids.
- Trial name
- EoE (NCT02314455)
- Testing
- D-xylose
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic