Clinical trials: Epidemic Disease
Covid19, Sars-CoV2
Description of Ophthalmologic Injuries in Intensive Care During the SARS-CoV2 Epidemic - COVID19
The management of patients with SARS-CoV2 in respiratory distress can expose to corneal or retinal lesions induced by the stay in intensive care.
- Trial name
- DOCOV (NCT04385810)
- Testing
- Ophthalmologic exam
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
SARS-CoV 2, Traumatic Stress Disorder
Consequences of the QUARANTINE Relating to the COvid-19 Epidemic on the Mental Health of the Patients Followed in PSYchiatry
Quarantine related to the Covid-19 pandemic has begun on the 03/17/2020 in France. Quarantine has already be linked to pejorative effects on mental health.
- Trial name
- QUARCOPSY (NCT04405362)
- Sponsor
- University Hospital, Lille
Stress, Psychological
Influence of the COvid-19 Epidemic on STRESS
The Coronavirus has a major influence on stress for the general population. However, data are currently non-existent concerning the perception and knowledge of the epidemic, the feeling of information from companies /…
- Trial name
- COVISTRESS (NCT04308187)
- Where
- France
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Diabetes
Impact of the COVID-19 Epidemic on Glycemic Balance and the Level of Stress in Diabetic Patients
Prospective, non-interventional, multicentric study
- Trial name
- COVIGLYSTRESS (NCT04924673)
- Where
- 11 sites in France
- Volunteers
- 202 people
- Sponsor
- Rennes University Hospital
Influenza
Control of Epidemic Influenza Through a School-based Influenza Vaccination Program
The main purpose of this study is to learn if influenza vaccines (live attenuated and inactivated influenza vaccines), when given to school-aged children 4 to 18 years of age, can stop or lessen the influenza (flu) outbreak in…
- Trial name
- CEI (NCT00138294)
- Testing
- live attenuated and inactivated influenza vaccines
- Where
- 2 sites in United States
- Volunteers
- 29,255 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Covid19, Burnout, Professional
Burnout, Stress and Coping Strategies: Impact of the Covid-19 Epidemic
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus detected in Wuhan, China on December 2019. This virus is responsible for the infectious respiratory disease called Covid-19.
- Trial name
- Au20-15 (NCT04834882)
- Testing
- Data collection (
- Where
- France
- Volunteers
- 649 people
- Sponsor
- CHU de Reims
Epidemic Parotitis,Mumps
Phase II of Live Attenuated Mumps (F-genotype) Vaccine (Human Diploid Cell, KMB-17) in Chinese Infants
Mumps is an acute infectious respiratory disease caused by the mumps virus (MuV), which occurs mainly in children and adolescents. Its main clinical symptoms were parotid gland suppurative swelling and pain with fever.
- Trial name
- NCT03133923
- Testing
- ≥3.0 lgCCID50/mlbut <3.5lgCCID50/ml Live Attenuated Mumps Vaccine (Human Diploid Cell) in infants(8-24 months old), ≥4.5 lgCCID50/ml Live Attenuated Mumps Vaccine (Human Diploid Cell) in infants(8-24 months old), Measles and Mumps Combined Vaccine，Live(SIBP)( positive control)
- Where
- China
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Covid19, Cancer
Impact of the COVID-19 Epidemic on the Hospital Journey of Patients With Cancer of the Digestive System
The hospital care of patients with cancerous pathology is part of a multidisciplinary care path that includes many stages. The treatment conditions in this course vary depending on the reasons that led to suspect the existence of…
- Trial name
- KOVID (NCT04616950)
- Where
- France
- Volunteers
- 274 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Post Partum Depression
Psychological Impact of the Lockdown on Patients Giving Birth During the COVID-19 Epidemic Short Title : Isolement and Childbirth: Psychological Impact
The COVID-19 epidemic has a major impact on the organization of hospital structures as a whole. Regarding the functioning of the Maternities, it was decided by the three Maternities of AP-HP.
- Trial name
- COVMUM (NCT04366817)
- Testing
- psychological assessment
- Where
- France
- Volunteers
- 287 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Direct Income SupporT and Advice Negating Spread of Epidemic COVID-19: a Randomized Controlled Trial
This is a clinical trial of a cash transfer on symptoms consistent with COVID-19 and adherence to physical distancing guidance.
- Trial name
- DISTANSE COVID (NCT04359264)
- Testing
- Cash transfer
- Where
- 2 sites in Canada
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Disease Outbreaks, Child
Predictive Tracking of Patient Flow in the Emergency Services During the Virus Winter Epidemics
Epidemics and infectious diseases in general, punctuate much of the activity of an emergency service. The impact of winter infections is particularly important to vulnerable populations such as infant during bronchiolitis…
- Conditions
- Disease Outbreaks, Child, Elderly, Bronchiolitis
- Trial name
- PREDAFLU (NCT02858531)
- Testing
- data retrieval
- Where
- 11 sites in France
- Volunteers
- 760,000 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Bronchiolitis
Using Nasal Broadband Glasses in the Initial Management of Severe Bronchiolitis in Infants Admitted in ICU
The aim of this study is to evaluate the use of nasal broadband glasses HFNC (High Flow Nasal Cannula) in the initial management of severe bronchiolitis in infants admitted in ICU.
- Trial name
- HFNC (NCT02791711)
- Testing
- High Flow Nasal Cannula
- Where
- 2 sites in France
- Volunteers
- 33 people
- Sponsor
- Fondation Lenval
Depression, Anxiety
Post-COVID-19 Epidemic Depression Assessment in Adults in South Punjab Pakistan
To assess the depression in adults especially in post COVID-19 duration in the rural and urban settings.
- Trial name
- NCT04604080
- Testing
- service of questionnaire
- Where
- 5 sites in Pakistan
- Volunteers
- 390 people
- Sponsor
- Islamia University of Bahawalpur
Viral Conjunctivitis
Therapeutic Efficacy of APD-209 Eye Drops in Treatment of Epidemic Keratoconjunctivitis (EKC)
A randomized, double-masked, placebo-controlled, multi-centre phase IIa proof-of-concept study to evaluate efficacy and safety of APD-209 Eye drops for treatment of acute phase adenovirus-induced EKC.
- Trial name
- NCT01977443
- Testing
- APD-209 Eye drops
- Where
- 10 sites in Germany, Poland and 1 more
- Volunteers
- 47 people
- Sponsor
- Adenovir Pharma AB
Covid19, Death
COVID-19 Infections and Mortality in Long-term Care Facilities During the First Wave
The medical charts of all COVID-19 cases (n=1200) from 17 long-term care facilities in Montreal, Canada will be reviewed, to compare patients who survived to patients who did not survive.
- Conditions
- Covid19, Death, Infection Viral, Infections, Respiratory
- Trial name
- NCT04782427
- Testing
- COVID-19 infection
- Where
- Canada
- Volunteers
- 1,197 people, healthy volunteers welcome
- Sponsor
- Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal
Left Ventricular Diastoic Dysfunction Cohort Study
Epidemic Profile of Left Ventricular Diastoic Dysfunction in the Community Elderly and Establishing Prediction Model: the Northern Shanghai Study
This study is one of the largest ongoing prospective population studies to evaluate target organ damages (TODs) and Left Ventricular Diastoic Dysfunction in the community-dwelling elderly Chinese, which is authorised and funded…
- Trial name
- ELITISM (NCT03735251)
- Testing
- Diuretic，Betaloc，antiplatelet drugs
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Ya-Wei Xu
Epidemic Meningitis
Phase IV Clinical Study of Immunogenicity of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector)
The purpose of this clinical study is to evaluate the immunogenicity and immunopersistence of the ACYW135 meningococcal polysaccharide conjugate vaccine (CRM197 vector).The protocol consists of two parts: Part 1 enrolled 660…
- Trial name
- NCT05935176
- Testing
- MCV4
- Where
- China
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Sars-CoV2
COVID-19 Seroconversion Among Front Line Medical and Paramedical Staff in Emergency, Intensive Care Units and Infectious Disease Departments During the 2020 Epidemic
The epidemic due to the Sars-CoV2 virus is spreading in France, without knowning precisely since when the virus has actually circulated on the territory.
- Trial name
- SEROCOV (NCT04304690)
- Testing
- blood sample
- Where
- France
- Volunteers
- 1,177 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bronchiolitis
Organizational Infrastructure Pediatric Plan in Bronchiolitis Epidemics
Acute bronchiolitis is a frequent respiratory viral infection of infants, responsible for 460,000 new cases per year in France. Over the years, the number of hospitalizations during the epidemic season appears to be increasing.
- Trial name
- OIPP (NCT03663660)
- Testing
- Organizational infrastructure pediatric plan (OIPP)
- Where
- France
- Volunteers
- 1,636 people
- Sponsor
- University Hospital, Montpellier
Opioid-use Disorder, Opioid Misuse
Comparing a Patient Self-Assessment Software to Treatment as Usual in Opioid Prescriber and Patient Opioid Outcomes
The Care Continuity Program (CCP), a product of Sure Med Compliance, is a novel, online patient self-assessment used by prescribers of opioids to better identify patient risk factors and therapy benefit.
- Conditions
- Opioid-use Disorder, Opioid Misuse, Opioid Use, Chronic Pain
- Trial name
- NCT04945525
- Testing
- Care Continuity Program
- Where
- United States
- Volunteers
- 1,840 people
- Sponsor
- Sure Med Compliance