Clinical trials: Epidural/Anesthesia
Umbilical Hernia, Postoperative Pain Management
Ultrasound-Guided Transversus Abdominis Plane Block Versus Epidural Block for Umbilical Hernia Analgesia
This observational study aims to compare the postoperative analgesic effectiveness of ultrasound-guided transversus abdominis plane (TAP) block and single-dose epidural anesthesia in patients undergoing umbilical hernia surgery.
- Trial name
- NCT07327463
- Testing
- Ultrasound-Guided Transversus Abdominis Plane Block, Single-Dose Epidural Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sakarya University
Anesthesia, Local Anesthesia
Can Caudal Dexmedetomidine Provide Effective Analgesia?
The goal of this clinical trial is to evaluate if caudal dexmedetomidine can provide effective analgesia during inguinoscrotal surgeries in pediatrics, if used caudally alone (and not as an adjunct to caudal bupivacaine).
- Trial name
- NCT05902780
- Testing
- Caudal Bupivacaine injection, Caudal Dexmedetomidine Injection
- Volunteers
- 50 people
- Sponsor
- Benha University
Epidural Analgesia, Nulliparous Pregnant
Evaluation of a Protocol Posturalchanges in Women Giving Birth With Epidural Analgesia. Clinical Trial.
. The pain that occurs during labor is controlled in our environment through epidural analgesia. This mainly generates a sensory block but also a motor block that suppresses different reflexes physiological factors that…
- Conditions
- Epidural Analgesia, Nulliparous Pregnant, Labor With Postural Changes, Randomized
- Trial name
- NCT05812560
- Testing
- postural changes
- Where
- Spain
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Arthroplasty, Replacement, Knee, Patient-controlled Analgesia
Postoperative Patient Controlled Epidural Analgesia After Total Knee Arthroplasty With 2ug/ml Fentanyl Combine With 0.2% Ropivacaine or 0.2% Levobupivcaine
Postoperative epidural analgesia (EA) is an effective and well-accepted modality of pain relief technique after having total knee replacement operation(1,4).
- Trial name
- NCT01158586
- Testing
- Levobupivacaine
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- United Christian Hospital
Postoperative Pain, Satisfaction with Care
Thoracic Spinal Versus Thoracic Epidural Anesthesia for Patients with Chronic Obstructive Pulmonary Disease Undergoing Supine Percutaneous Nephrolithotomy for Management of Renal Stones.
Owing to the elevated risk of perioperative comorbidities, chronic obstructive and restrictive pulmonary disorders can be a challenging task for the anesthetist.
- Trial name
- NCT06663488
- Testing
- Thoracic epidural anesthesia, Thoracic spinal anesthesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Epidural Block, Electrical Impedance Tomography
Epidural Block Impairs HPV During One-lung Ventilation: an EIT- Based Prospective Observation Study
Define the effect of epidural block on HPV by EIT.
- Trial name
- NCT04730089
- Testing
- Electrical impedance tomography
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Zhongshan Hospital
The Efficacy of Analgesic Methods After Caesarean Section
Establishment and Evaluation of a Post Caesarean Acute Pain Service (PCAPS)
The aim of this study is to compare the efficacy of analgesic methods after Caesarean Section before and after Post Caesarean Acute Pain Service establishing.
- Trial name
- PCAPS (NCT02062320)
- Where
- Czechia
- Volunteers
- 407 people
- Sponsor
- Brno University Hospital
Colorectal Surgery
Effect of Anesthesia on Insulin Secretion in Patients With Preoperative Decreased Insulin Sensitivity
Epidural anesthesia has been found to manipulate the hyperglycemic response to surgery. It is unclear, however, whether the preoperative metabolic status of the surgical patient plays a role in the degree of this hyperglycemic…
- Trial name
- NCT01739413
- Testing
- Anesthesia
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Gabriele Baldini, MD, MSc, Assistant Professor
Cancer of Pancreas, Cancer of the Pancreas
Epidural Analgesia Use in Pancreatic Resections
The rationale for this study is to investigate the benefits of epidural analgesia in pancreatic resections in a prospective, single blind, randomized control trial.
- Conditions
- Cancer of Pancreas, Cancer of the Pancreas, Pancreas Cancer, Pancreas Neoplasms
- Trial name
- E-PRO I (NCT02681796)
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Washington University School of Medicine
Lung Cancer
Thoracoscopic Lobectomy Using Nonintubated Anesthesia Versus Intubated General Anesthesia for Lung Cancer Patients
The purpose of this study is to study the safety and results of thoracoscopic lobectomy using non-intubated thoracic epidural anesthesia versus intubated general anesthesia for lung cancer patients.
- Trial name
- NCT01533233
- Testing
- thoracoscopic lobectomy and mediastinal lymph node dissection
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Open Gastrectomy With Gastric Cancer
Comparison of Analgesic Effects According to Patient-controlled Epidural Analgesia Modes in Patients Undergoing Open Gastrectomy
Epidural PCA (patient controlled analgesia) for post-operative pain management are effective analgesic method. It is widely used in the postoperative pain management for decades.
- Trial name
- NCT03430440
- Testing
- Apply CIPKA mode, Conventional mode
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Yonsei University
Cesarian Section, Neonatal and Perinatal Conditions
Transplacental Neonatal Transfer of Lidocaine During Urgent Caesarean Delivery
Lidocaine is commonly administered through an existing labor epidural catheter to provide surgical anesthesia for urgent cesarean delivery.
- Conditions
- Cesarian Section, Neonatal and Perinatal Conditions, Epidural Anesthesia, Lidocaine Toxicity
- Trial name
- Lidocaine TNT (NCT07826468)
- Testing
- Category Lucas 1 cesarian section, Category 3 Lucas Cesarian section
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Hôpital de la Croix-Rousse
Labouring Parturients Requiring/Requesting Epidural Analgesia as Part of Their Peri-partum Care
A Comparison Study Of Two Different Techniques For Identifying The Epidural Space In Parturients In Labour
The purpose of this study is to determine whether the use of the Epidrum device to identify the epidural space in labouring parturients reduces morbidity, when compared to standard loss of resistance techniques.
- Trial name
- NCT01574391
- Testing
- Epidrum
- Where
- Ireland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Maternity Hospital, Ireland
Combined Spinal-epidural Anesthesia
Relationship Between ANI, Anxiety, and Pain in Conscious Hernia Patients Undergoing CSEA
Analgesia Nociception Index can be used to detect noxious stimulation during general anesthesia.The aim of this study is to observe ANI under combined spinal epidural anesthesia procedures in conscious hernia patients.
- Trial name
- NCT05053633
- Testing
- Combined spinal epidural anesthesia
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Beijing Chao Yang Hospital
Urinary Tract Infections
Early or Late Foley Removal After Thoracotomy
Is the early removal of Foley catheter safe in patients undergoing general thoracic surgery with an epidural catheter in place?
- Trial name
- NCT01611519
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Open Colorectal Surgery, Early Rehabilitation After Surgery
Continuous Preperitoneal Infusion of Local Anesthetic (CPA) Versus Epidural Infusion of Local Anesthetic (EA) in Fast-Track Open Colorectal Surgery
The purpose of this study is to compare the continuous preperitoneal infusion of local anesthetic and continuous epidural analgesia for postoperative pain management in fast-track open colorectal surgery.
- Trial name
- NCT00915265
- Testing
- Multilobed catheter (group CPA), Multilobed catheter (group EA)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Morbid, Pregnancy
3D Ultrasound-guided Labor Epidural Analgesia in the Morbid Obese Parturient
This study will be a randomized control study, with the objective to evaluate epidural analgesia success rates between the two methods (Blind Approach versus Accuro Device).
- Conditions
- Obesity, Morbid, Pregnancy, Pain
- Trial name
- NCT03405311
- Testing
- Rivanna Accuro 3D Ultrasound Device, Palpation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Duodenal Neoplasm, Pancreatic Neoplasm
Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
This phase II trial compares the effect of rectus sheath block with liposomal bupivacaine to thoracic epidural analgesia (TEA) on pain control in patients following surgical removal of all or part of the pancreas and duodenectomy…
- Trial name
- NCT06411795
- Testing
- Bupivacaine, Hydromorphone, Iopamidol
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Lung Neoplasms, Pain
Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study
Whereas it, in the case of conventional thoracotomy, has been demonstrated that thoracic epidural analgesia is more effective than systemic opioids in terms of pain relief and preservation of postoperative pulmonary function, the…
- Conditions
- Lung Neoplasms, Pain, Immune Suppression
- Trial name
- SEAVATS (NCT02359175)
- Testing
- Bupivacaine in epidural catheter, Fentanyl in epidural catheter, Oral Paracetamol
- Where
- Denmark
- Volunteers
- 161 people
- Sponsor
- Odense University Hospital
Breakthrough Pain
Comparison of Regimens MPIB, CIPCEA, PCEA
Epidural analgesia is the gold standard of pain relief for labour pain. Despite this, more than 50% of parturients continue to experience pain leading to suffering and increased caregiver workload.
- Trial name
- COLEUS (NCT02278601)
- Testing
- epidural delivery system, Ropivacaine, Fentanyl
- Where
- Singapore
- Volunteers
- 839 people
- Sponsor
- KK Women's and Children's Hospital