Clinical trials: Epidural/Anesthesia
Epidural Analgesics for Comparison
Epidural Anesthesia for Gynecological Surgeries
Regional anesthesia is the preferred mode of anesthesia for major abdominal surgeries in present times. Gynecological surgeries are often associated with severe pain requiring a well-planned analgesia regimen to ensure adequate…
- Trial name
- NCT04174872
- Testing
- Dexmedetomidine, Midazolam
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labor, Obstetric, Pain
Estimation of Pain During Epidural Analgesia During Labor
Epidural regional anesthesia is a technique to eliminate or lessen pain during obstetric labor and childbirth. It consists in establishing a catheter into the epidural space and to block the transmission of pain sensations by…
- Trial name
- PERIDANS (NCT02551354)
- Testing
- Portable video pupillometer
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Labor Pain
Ten-year Practice of Labor Pain Control in China
Since 1999, labor pain control has being performed in China, and the initial time of analgesia is at the cervix >= 2 cm. Meanwhile, American Society of Obstetrics \& Gynecology recommended that the labor analgesia with neuraxial…
- Trial name
- POPIC (NCT00776581)
- Testing
- CSEA with PCA, CSEA with IBI, EA with PCA
- Where
- China
- Volunteers
- 40,000 people
- Sponsor
- Nanjing Medical University
Neuraxial Technique
Accuracy of the Accuro 3S
The main purpose of this study is to evaluate the feasibility and accuracy of the Accuro 3S to provide live guidance when performing a neuraxial technique (e.g., spinal, or epidural).
- Trial name
- NCT07458087
- Testing
- ACCURO 3S
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Psychological Well Being
The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During and After Unexpected Cesarean Delivery Under Neuraxial Anesthesia to Inform Anesthetic Practice
This study aims to explore the patients' and providers' perspectives and inform future anesthetic practice for patients undergoing unexpected cesarean delivery (CD) under neuraxial anesthesia (NA).
- Trial name
- PAS-EDU-uCD-NA (NCT06589687)
- Testing
- Interview
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Lower Limb Injuries
Comparative Study of Bupivacaine and Ropivacaine in Lumber Epidural Lower Limb Bypass Surgery
Regional anaesthesia is an important part in clinical anaesthesiology now a day. Epidural block is a commonly used regional technique alternative for general anaesthesia in case of lower limb bypass surgery.
- Trial name
- NCT06677697
- Testing
- Ropivacaine 0,5%
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- ibrahim cardiac hospital and research institute
Cesarean Section, Pregnancy Related
Brain Oxygenation in Newborns Due to Neuroaksial Methods
Epidural and spinal anesthesia techniques are frequently used all over the world in elective cesarean section operations. To evaluate the effects of epidural and spinal anesthesia techniques applied in cesarean section surgery on…
- Conditions
- Cesarean Section, Pregnancy Related, Cerebral Hypoxia, Anesthesia, Regional
- Trial name
- oxygenation (NCT06316596)
- Testing
- Spinal Anesthesia, Epidural Anesthesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Hypospadias, Postoperative Pain
Caudal Epidural Block and DPNB in Hypospadias
Hypospadias, seen in every 200-300 births, is one of the most common congenital anomalies of the penis and is defined as the urethral meatus being located in the ventral part of the penis instead of its normal place.
- Trial name
- NCT04215874
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pregnancy, Labor and Delivery
Ropivacaine and Fentanyl for Labor Epidural Initiation
This study is being done to determine the most effective dose of medicine to use to initially provide effective pain relief within the first 30 minutes of receiving an epidural for pain labor during labor.
- Conditions
- Pregnancy, Labor and Delivery, Labor Analgesia
- Trial name
- EV90_DPE (NCT07076368)
- Testing
- Ropivacaine + Fentanyl
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Pregnancy Related
Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia
The purpose of this randomized controlled trial is to compare the effectiveness of epidural clonidine, dexmedetomidine, or fentanyl adjuncts for labor analgesia.
- Trial name
- NCT05487196
- Testing
- Clonidine, Dexmedetomidine, Fentanyl
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Early Confirmation of Epidural Catheterization
Early Detection of Epidural Onset by Temperature Change
Traditionally, placement of the epidural catheter is based on hand feel of passing through the ligamentum flavum as well as "loss of resistance" while injecting the air through the needle.
- Trial name
- NCT02838056
- Testing
- epidural injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University WanFang Hospital
Pregnancy
Sleep Efficiency and Quantification After Labor Epidural Analgesia
The specific aim is to attempt to quantify the amount and efficiency of sleep that parturients receive after placement of labor epidural analgesia.
- Trial name
- Actiwatch (NCT02862951)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Virginia
Regional Anaesthesia in Cesarean Operations
Comparison of Dural Puncture Epidural and Standard Epidural Anesthesia Techniques in Elective Cesarean Deliveries
Neuraxial techniques are the most effective form of labor analgesia in contemporary obstetric anesthesia practice, predominantly through the use of epidural (EPL) and combined spinal-epidural (CSE) techniques.
- Trial name
- NCT07295080
- Testing
- Dural puncture epidural (DPE) anaesthesia, standart epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Vaginal Delivery
Failed Epidural Anesthesia During Labor: Evaluation of Risk Factors and Outcome
Women requesting epidural analgesia will receive a bolus of intravenous infusion of lactated Ringer's solution before initiation of the procedure.
- Trial name
- NCT03129022
- Testing
- epidural anaesthesia
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Pain, Postoperative
Ultrasonography for Confirmation of Caudal Injection
The purpose of our study is to evaluate whether utilizing ultrasound assessment during caudal epidural injection can reliably identify unrecognized and unsuccessful nerve blocks during the procedure, guide proper technique, and…
- Trial name
- NCT02321787
- Testing
- Ultrasound for confirmation of successful caudal block
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Ambulatory Epidural
Assessment of the Expectations and Fears of Pregnant Patients Monitored at the CMCO Regarding Ambulatory Epidural Anesthesia
Ambulatory epidural anesthesia is a technique that has been described since the late 1990s and has been rapidly gaining popularity in recent years.
- Trial name
- Déambu-Péri (NCT07345962)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Immunity Factors in Cancer Colon Patients
Epidural-inhalational Versus Epidural-intravenous Anaesthesia on Anti-tumor Immunity in Patients With Cancer Colon
Surgery is the primary treatment for colon cancer. However, the rate of recurrence or metastasis in colon cancer can be as high as 30%, even in stages 1 and 2 . Most colon cancer-related deaths are caused by metastatic disease .
- Trial name
- tumorimmunity (NCT04518579)
- Testing
- thoracic epidural
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- South Egypt Cancer Institute
Anesthesia
Dexmedetomidine Versus Fentanyl Plus Bupivacaine for Epidural Analgesia With General Anesthesia for Lumbar Disc Operations
The purpose of this study is to compare addition of dexmedetomidine or fentanyl to bupivacaine for epidural analgesia in combination with general anesthesia in elective lumbar spine operations as regard hemodynamic stability…
- Trial name
- NCT03438240
- Testing
- Bupivacaine, Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Obstetric Pain, Other Complications of Obstetric Anesthesia - Delivered
Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome
To assess the efficacy of epidural dexamethasone administration, compared to placebo, in reducing local anesthetics consumption during labor epidural analgesia in parturient women
- Trial name
- DEXAPER (NCT02857465)
- Testing
- Dexamethasone, Ropivacaine, Sufentanil
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pain Management, Pain, Postoperative
Preperitoneal Analgesia Versus Epidural Analgesia After Open Pancreaticoduodenectomy
This is a prospective randomized open-label noninferiority trial that compares thoracic epidural analgesia and continuous preperitoneal analgesia after open pancreaticoduodenectomy.
- Trial name
- Pain (NCT04375826)
- Testing
- Epidural patient controlled analgesia, Preperitoneal analgesia and IV-PCA
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Seoul National University Hospital