Clinical trials: Epidural/Anesthesia
Epidural Anesthesia, Shivering
The Effect of Oral Pregabalin on Epidural-induced Shivering and Epidural Characteristics
Background: The previous reports tried to reduce shivering and improve neuroaxial anesthesia characteristics by the systemic use of different drugs.
- Trial name
- NCT03721432
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Beni-Suef University
Labor Pain
Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural Analgesia in Laboring Women
Combined spinal-epidural (CSE) for labor analgesia has been used for many years and is practiced commonly at our institution, especially when the patient requests immediate pain relief.
- Trial name
- NCT05512065
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Elderly, Malignant Tumor
Epidural Anesthesia-analgesia and Long-term Outcome
Surgical resection is one of the most important treatments for resectable cancer; on the other hand, cancer recurrence and/or metastasis are the major reasons of treatment failure.
- Conditions
- Elderly, Malignant Tumor, Surgical Resection, Epidural Anesthesia
- Trial name
- NCT03012945
- Testing
- Combined epidural-general anesthesia, General anesthesia
- Where
- 5 sites in China
- Volunteers
- 1,802 people
- Sponsor
- Peking University First Hospital
Shivering, Labor
Investigating the Effect of Acupressure on Shivering During a Cesarean Delivery in Women Who Were Previously Laboring With an Epidural
Shivering during a cesarean section can be quite uncomfortable for the patient as well as make it difficult for the anesthesiologist to obtain vital signs.
- Conditions
- Shivering, Labor, Cesarean Delivery
- Trial name
- NCT03497507
- Testing
- Acupressure bracelet
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Well-Being, Psychological
The Patient AS EDUcator in Anesthesia: Exploring the Patients' and Providers' Experience During Neuraxial Labour Analgesia
During the process of labour and delivery, patients may experience a wide range of events in a short time frame. This study focuses on exploring these experiences and aims to incorporate the improvements from these experiences so…
- Trial name
- PAS-EDU-NLA (NCT06368583)
- Testing
- Interview
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Thoracotomy, Sternotomy
Does Thoracic Epidural Analgesia Influence Urinary Micturition by Patients Undergoing Thoracic Surgery?
Under the influence of epidural analgesia, patients may not feel the urge to urinate, which can result in urinary retention and bladder overdistension.
- Trial name
- NCT00976313
- Testing
- Assessment of urinary micturition after thoracotomy, International Prostate Symptom Score
- Where
- Switzerland
- Volunteers
- 26 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anesthesia; Adverse Effect, Spinal and Epidural
Comparative Study Between Bilateral and Unilateral Spinal Anaesthesia
The purpose of this study is to compare unilateral spinal anesthesia using hyperbaric Prilocaine with "classical bilateral spinal anesthesia" using plain Prilocaine according to block characteristics and quality of micturition…
- Trial name
- NCT01877356
- Testing
- bilateral spinal anesthesia, unilateral spinal anesthesia
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Antwerp
Medical Education, Resident Education
Impact of Mental Training on the Stress of Anaesthesiology Residents Before Performing Obstetrical Epidural Analgesia
Anaesthetists are trained from the beginning of their residency to perform high-risk procedures, often in high-stress environments, that can adversely affect both their technical and non-technical performance.
- Conditions
- Medical Education, Resident Education, Anesthesia, Epidural Analgesia, Obstetric
- Trial name
- NCT07183618
- Testing
- Mental training group
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia
Evaluation of Plasma Concentrations of Intravenous Lidocaine and Epidural Ropivacaine When Used in Combination in Major Abdominal Surgery
Thoracic epidural analgesia (TEA) is the gold standard analgesia of the laparotomy in major abdominal surgery and can be associated with intravenous lidocaine or subtituted by intravenous lidocaine when TEA is contraindicated and…
- Conditions
- Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia, Analgesia, Lidocaine Adverse Reaction
- Trial name
- LARA (NCT05368753)
- Testing
- Blood sample, Lidocain, ropivacaine
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Urinary Retention
Evaluation of the Efficacy of the Addition of Magnesium Sulfate to Morphine on the Occurrence of Acute Urinary Retention Following Epidural Anesthesia for Cesarean Section.
Peri-medullary anesthesia is the preferred anesthetic technique for Caesarean surgery. Compared with general anesthesia, it reduces maternal and fetal morbidity and mortality, as well as postoperative pain.
- Trial name
- EPIMAG (NCT06442995)
- Testing
- Injection of 500 mg magnesium sulfate + 2 mg morphine into the epidural space, Injection of Isotonic saline + 2 mg morphine into the epidural space
- Where
- France
- Volunteers
- 290 people
- Sponsor
- CHU de Reims
Cesarean Section, Anesthesia, Spinal
Combined Spinal-epidural Anesthesia for Cesarean Section Without Prophylactical Prehydration and Vasopressors
Hypotension is a common complication in pregnant women after spinal anesthesia and related with the dose of local anesthetic. Injecting small dose local anesthetic into subarachnoid space can decrease the incidence of…
- Trial name
- CSEAFCSWPPAV (NCT03497364)
- Testing
- bupivacaine, ropivacaine
- Where
- China
- Volunteers
- 930 people
- Sponsor
- Shenzhen People's Hospital
Urological Disease, Anesthesia
To Map Human Lower Thoracic Dermatomes by Epidural Block
Significant differences exist among various dermatome maps. In addition, there were no anatomical landmarks to evaluate the dermatome at the back.
- Trial name
- LTDEP (NCT03022136)
- Testing
- cold sensation method
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tongji Hospital
Analgesia
Comparison Of Epidural Analgesia Techniques In Percutaneous Nephrolithotomy With Surgical Pleth Index
Primary aim of this study is to evaluate affect of SPI guided antinociception on total intraoperative consumption of local aneshesics during analgesia.
- Trial name
- NCT05572164
- Testing
- TRADITIONAL EPIDURAL, DURAL PUNCTURE EPIDURAL
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anesthesia
Loss of Resistance, w/wo Stimulation, For Epidural Placement
The purpose of this randomized, observer-blinded, investigative trial is to determine if the use of electrical stimulation, compared to the traditional loss of resistance technique alone, improves the success rate of epidural…
- Trial name
- NCT03087604
- Testing
- Thoracic epidural block, Electrical Nerve stimulation, Solution For Thoracic epidural block
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences
Postoperative Pain
Postoperative Pain Relief After Major Abdominal Gynecological Surgery
The aim of our study was to compare the effects of Lomber Epidural Analgesia (LEA), Transversus Abdominis Plane (TAP) block and Local Anesthetic Infiltration (LAI) on postoperative morphine consumption, time to first recue…
- Trial name
- NCT05845385
- Testing
- lumbar epidural analgesia with bupivacaine, transversus abdominis plane block with bupivacaine, wound infiltration with bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Obstetric Labor
Carbohydrate-Optimized Nutritional Solution Versus Electrolyte Hydration in Labor
This is a pilot randomized, triple-blind clinical trial (pilot RCT) evaluating the preliminary effects of energy supplementation with carbohydrate-rich sports gels compared to a low-sugar sports drink during labor in low-risk…
- Trial name
- NCT07742748
- Testing
- High carbohydrate sports gel, Low carbohydrate hydrogel
- Where
- Spain
- Volunteers
- 147 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural
Non-invasive Cardiac Output Monitoring in Obstetric Patients
The investigators hypothesize that continuously measuring stroke volume (SV) and cardiac output (CO) will 1) reveal hemodynamic instability in a timely manner and alert the physician promptly, 2) provide information for the…
- Trial name
- NCT01516697
- Testing
- experimental, Control
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Pregnancy, Anesthesia
Continuous Noninvasive Method for Estimating and Predicting Maternal and Fetal Hemodynamic Changes During Regional Anesthesia
Machine learning techniques and algorithms originally developed for use in the field of robotics can be applied to continuous, noninvasive physiological waveform data to discover hidden, hemodynamic relationships.
- Trial name
- NCT01699243
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Colorado, Denver
Obesity/therapy
Rhomboid Intercostal Block with Subserratus Plane Block in Bariatric Surgery
Standard analgesic techniques such as patient-controlled analgesia (PCA) and continuous epidural analgesia (CEA) are effective but associated with considerable side effects, including nausea, hypotension, and respiratory…
- Trial name
- NCT06729515
- Testing
- PCA, CEA, RISS
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xiaguang Duan
Effects of; Anesthesia, in Labor and Delivery
Intrathecal Dexamethasone and Labor Analgesia
To evaluate the effectiveness of adding dexamethasone to intrathecal levobupivacaine in combined spinal epidural (CSE) analgesia during vaginal delivery.
- Trial name
- NCT02588417
- Testing
- Dexamethasone, Levobupivacaine
- Volunteers
- 80 people
- Sponsor
- ahmed elsakka