Clinical trials: Epidural/Anesthesia
Analgesia, Epidural, Pain, Postoperative
Programmed Intermittent Bolus Versus Continuous Infusion for Epidural Analgesia in Abdominal Surgery
Epidural analgesia is an efficient way to relieve pain after major abdominal surgery. Two different protocols are used to provide analgesia: continuous epidural infusion (CEI) and programmed intermittent boluses (PIEB).
- Trial name
- NCT04254523
- Testing
- Programmed intermittent epidural bolus (PIEB) of bupicavaine, Continuous epidural infusion (CEI) of bupivacaine, Continuous epidural infusion (CEI) of morphine
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- CHU de Quebec-Universite Laval
Obstetric Anesthesia Problems, Headache
Post-dural Puncture Headache: A Retrospective Study
Neuraxial techniques are widely used in obstetric practice to provide analgesia and anesthesia. A common complication associated with neuraxial anesthesia is post-dural puncture headache (PDPH), resulting from unintentional or…
- Conditions
- Obstetric Anesthesia Problems, Headache, Epidural; Anesthesia, Headache
- Trial name
- NCT03790124
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Augusta University
Extended Ileal Resection Under Laparotomy, Total Proctocolectomy Under Laparotomy
Postoperative Analgesia in Abdominal Surgery: a Medico-economic Study
Background : Epidural anaesthesia is associated in abdominal surgery with reduced pain and postoperative respiratory complications together with quicker recovery of bowel function.
- Conditions
- Extended Ileal Resection Under Laparotomy, Total Proctocolectomy Under Laparotomy, Colectomy Left/Right/Total Under Laparotomy, Rectosigmoidal Resection Under Laparotomy
- Trial name
- PERIDIGE (NCT01470846)
- Testing
- epidural analgesia, PCA
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Limoges
Pain, Postoperative, Opioid Use
Therapeutic Efficacy of Intravenous Lidocaine Infusion Compared With Epidural Analgesia for Postoperative Pain Control in Adult Patients Undergoing Major Abdominal Surgery: Non-Inferiority Clinical Trial
Major abdominal surgery continues is one of the most performed surgical procedures in the world, both electively and urgently. One of the main problems of this type of intervention is postoperative pain.
- Trial name
- NCT04017013
- Testing
- Epidural Analgesia, Lidocaine Infusion
- Where
- Colombia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Anesthesia, Radical Mastectomy
Analgesic Efficacy of Ultrasound Guided Serratus Anterior Plane Block and Pectoral Nerve Block II
Modified Radical Mastectomy accounts for 31% of all breast surgeries and considered the fundamental surgical management for breast cancer. Nearly 40-60% of patients experience severe acute postoperative pain.
- Trial name
- NCT06188156
- Testing
- Anethesia
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Al-Azhar University
Colorectal Carcinoma, Analgesia, Postoperative
Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery
Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing…
- Conditions
- Colorectal Carcinoma, Analgesia, Postoperative, Laparotomy
- Trial name
- NCT06935708
- Testing
- Intrathecal Morphine, Epidural Analgesia
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- Meri Mirceta
Pregnancy Complications, Atelectasis
Effect of Epidural Analgesia on Regional Lung Ventilation in Parturient Women as Assessed by Thoracic Impedance
The goal of this observational study is to learn more about the effect of obstetric epidural anesthesia on regional lung ventilation in healthy parturient women.
- Trial name
- NCT06195774
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital
Fever, Labor Pain
Maternal Epidural Steroids and Hyperthemia
The purpose of this study is to look to see if adding steroids to an epidural reduces the chances of having a fever in labor, and protects the baby from exposure to inflammation.
- Conditions
- Fever, Labor Pain, Complication of Anesthesia During Pregnancy, Unspecified
- Trial name
- NCT02212210
- Testing
- Methylprednisolone, Normal saline
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Medical University of South Carolina
Labor Epidural Analgesia
PIEB vs PCEA With Epidural or CSE Technique. A Randomized Double Blind Clinical Trial
The investigators have design a randomized double blind clinical trial to know the incidence of breaktrough pain (BP) in high-risk of BP parturients (nulliparous with early cervical dilation) comparing two epidural analgesic…
- Trial name
- PIEB-CT (NCT02768272)
- Testing
- PCEA vs PIEB, Epidural vs CSE
- Where
- Spain
- Volunteers
- 240 people
- Sponsor
- Hospital Universitario La Paz
Cervical Cancer, Endometrial Cancer
Epidural Analgesia or Patient-Controlled Analgesia in Treating Patients Who Have Undergone Surgery for Gynecologic Cancer
RATIONALE: Giving pain medication into the space between the wall of the spinal canal and the covering of the spinal cord or giving it into a vein may help lessen pain caused by cancer surgery.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00295945
- Testing
- fentanyl citrate, hydromorphone hydrochloride, ropivacaine hydrochloride
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of California, San Francisco
Pain, Beta-endorphin
Double-blind, Randomized Controlled Study to Assess the Analgesic Effect of 2 g of Magnesium Dipyrone (Metamizol) and Changes in Plasma Beta-endorphin Immunoreactivity Values in Patients Undergoing Elective Inguinal Herniorrhaphy Under Epidural Anesthesia.
A double-blind, randomized controlled study is designed to assess the analgesic effect of a single intravenous dose of 2 g of magnesium dipyrone (metamizol) and whether the administration of the active drug will be associated…
- Conditions
- Pain, Beta-endorphin, Dipyrone, Hernia Surgery
- Trial name
- NCT04595877
- Testing
- Dipyrone administration, Pain assessment, beta-endorphin immunoreactivity
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Antonio Martín Duce
Pain
Is the Efficacy of Epidural Steroid Injections Related to the Different Volume Injections?
This study was aimed to investigate the impact of using different epidural volumes. Patients with acute discogenic pain were included in the study.
- Trial name
- NCT02343432
- Testing
- Triamcinolone, Epidural Volume, Bupivacaine
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Neslihan Uztüre
Pain, Postoperative
Pediatric Caudal Dexmedetomidine Enhances Postoperative Analgesia of Magnesium Sulphate in Lower Abdominal Surgeries
The study will conduct to compare the efficacy of Magnesium sulphate \& dexmedetomidine used as adjuvants to bupivacaine in caudal block to provide intra-operative anesthesia as well as post -operative analgesia in pediatric…
- Trial name
- JASayed (NCT02487355)
- Testing
- Dexmedetomidine, Magnesium Sulphate, Bupivacaine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Labor, Epidural Analgesia
Effect of Epidural Analgesia on the Length of Labor and Delivery and Fetal Outcomes
The purpose of this study is to determine if there is a difference in the duration of the first and second stage of labor in nulliparous women , with or without epidural analgesia.
- Conditions
- Labor, Epidural Analgesia, Nulliparous
- Trial name
- NCT02396563
- Testing
- epidural analgesia, Ropivacaine
- Volunteers
- 100 people
- Sponsor
- University of Cagliari
Analgesia, Obstetrical
SKIN WHEAL - Subcutaneous or Intradermal Lidocaine in Epidural for Laboring Pain.
The purpose of this study is to explore the differences between the pain associated with epidural Tuohy needle insertion with prior administration of subcutaneous or intradermal lidocaine using two different pain assessment tools…
- Trial name
- NCT06236126
- Testing
- 1% Lidocaine Injection
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pancreatic Cancer
Use of Epidurals Intraoperatively for Patients Undergoing Pancreas Resection
The purpose of this study is to see if there is a difference in complications in patients who have an epidural started earlier (during their surgery) and used as part of the anesthetic in addition to using it for post operative…
- Trial name
- NCT03434678
- Testing
- Propofol+ Rocuronium+ Fentanyl 2 mcg/kg+ Inhalational Agent, Bupivacaine 0.125% + Fentanyl 5 mcg/ml, Propofol+ Rocuronium+ Fentanyl + Inhalational, Open Pancreaticoduodenectomy
- Where
- 3 sites in United States
- Volunteers
- 133 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Post-Dural Puncture Headache
Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study
The purpose of this study is to determine the effect of 19g versus =>18g traditional Tuohy-type epidural needles on the incidence and severity of postdural puncture headache (PDPH).
- Trial name
- NCT00370604
- Testing
- 19g Tuohy-type epidural needle, 23g catheter, => 18g Tuohy-type needle
- Where
- 4 sites in Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Anesthesia
Chloroprocaine for Continuous Epidural Analgesia in Neonates and Infants
This a study to retrospectively review our experience with the use of chloroprocaine for postoperative epidural infusions in neonates and infants.
- Trial name
- NCT02207855
- Testing
- Chloroprocaine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Joseph D. Tobias
Anesthesia, Epidural, Pregnancy
Study PIEB vs PIEB: the Dose is it Variable According to the Patients
the main objective of this study is to compare the effectiveness of three groups of epidurals with three different programmed intermittent epidural bolus (PIEB)settings.
- Trial name
- DOPABIEB (NCT03690271)
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Rennes University Hospital
Post-Dural Puncture Headache
EPiMAP Obstetrics: European Practices in the Management of Accidental Dural Puncture in Obstetrics
The aims of EPiMAP Obstetrics are: to identify risk factors for failure of epidural blood patch in the obstetric population for management of post dural puncture headache.
- Trial name
- EPiMAP (NCT02362828)
- Where
- Sweden
- Volunteers
- 1,110 people
- Sponsor
- European Society of Anaesthesiology