Clinical trials: Epidural/Anesthesia
Colonic Neoplasms
Influence of Epidural Analgesia on Natural Killer Cell (NK) Activity After Colonic Cancer Surgery
Regional anesthesia may decrease the release of endogenous opioids, increase Natural Killer cell (NK) function and decrease development of metastasis.
- Trial name
- NCT02326727
- Testing
- Ropivacaine, Fentanyl, Propofol
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center
Post-dural Puncture Headache, Post-dural Puncture Backache
Long-term Effects of Accidental Dural Puncture in Patients Having Had an Epidural Blood Patch (LEAP)
Accidental dural puncture (ADP) during placement of an epidural catheter for anesthesia and analgesia is a well known complication. Previous studies have found audiometric deterioration following ADP.
- Trial name
- LEAP (NCT02149680)
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Labor Pain
Epidural Analgesia Versus IV Meperidine for Labor Pain Control
60 female that care for pain control during second stage of delivery, will choose between epidural or systemic analgesia. Continuous ECG (3 lead)monitoring will be recorded during the second stage for 10 minutes.
- Trial name
- NCT00296751
- Testing
- ECG recording, Epidural catheter insertion, Intravenous meperidine injection
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Labor Pain
Gender of Anesthesiologist and Time to Labor Epidural
The goal of this retrospective cohort study is to learn about wether the gender of the anesthetist affects time to epidural anesthesia (EDA) for laboring women . The main questions it aims to answer are: 1.
- Trial name
- NCT05744570
- Testing
- Epidural anesthesia
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Umeå University
Acute Pain, Surgery
Comparison of Epidural and TAP Block in Abdominal Surgery
This study will compare the infiltrative transversusabdominis plane (TAP) block with liposomal bupivacaine to epidural analgesia (EA) in major abdominal surgery .
- Conditions
- Acute Pain, Surgery, Regional Anesthesia
- Trial name
- NCT01848951
- Testing
- Epidural, TAP Block
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Nebraska
Laparoscopic, Nephrectomy
Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy.
Laparoscopic nephrectomy is a surgical technique to excise a diseased kidney. It's a minimally invasive technique, so when compared to open surgery, it can mean significantly less post-operative pain, shorter hospital stay…
- Conditions
- Laparoscopic, Nephrectomy, Anesthesia, Epidural
- Trial name
- NCT04546230
- Testing
- Low-Thoracic Epidural Anesthesia, General Anesthesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Nazmy Edward Seif
Labor Pain
Analgesic Efficacy of a Multiport Versus Uniport Flexible Catheter for Labor Epidural Analgesia
The purpose of this study is to determine whether multiple ports improve the analgesic efficacy of flexible catheters used for the provision of epidural analgesia during the entire continuum of labor and delivery
- Trial name
- NCT01861821
- Testing
- Multiport flexible catheter, Uniport flexible catheter
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- Baylor Research Institute
Anesthesia, Safety Issues
Sonographic Predictors of Difficult Epidural Placement.
Epidural placement is a commonly used procedure for pain management during labor, delivery, and surgeries. However, epidural placement is often considered a technically challenging and complex procedure that requires a high level…
- Conditions
- Anesthesia, Safety Issues, Epidural; Anesthesia, Headache
- Trial name
- PREC-EPI (NCT05893264)
- Testing
- Data collection
- Where
- Italy
- Sponsor
- University of Padova
Upper Abdominal Surgery
Subcostal Transversus Abdominis Plane Versus Epidural Block in Abdominal Surgeries
The investegators aimed to compare the efficacy of subcostal Transversus abdominis plane analgesia, to epidural analgesia intra and postoperatively in upper abdominal surgeries.
- Trial name
- NCT03949452
- Testing
- Subcostal Transversus Abdominis Plane catheter, Epidural catheter
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Mansoura University
Ceserean Section, Obstetric Quality of Recovery
Anesthetic Technique and Quality of Recovery After Cesarean Delivery
The goal of this prospective observational study is to evaluate whether the type of neuraxial anesthesia is associated with postoperative quality of recovery in adult women undergoing cesarean delivery.
- Conditions
- Ceserean Section, Obstetric Quality of Recovery, Neuraxial Anesthesia
- Trial name
- NCT07896733
- Testing
- Spinal anesthesia (heavy bupivacaine), epidural anesthesia, combine spinal epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Marmara University
Thoracic Epidural Anesthesia, Paravertebral Block
Thoracic Epidural Anesthesia Versus Paravertebral Block for Awake Thoracotomy
This study aims to compare paravertebral block and thoracic epidural in awake thoracotomy.
- Conditions
- Thoracic Epidural Anesthesia, Paravertebral Block, Awake Thoracotomy
- Trial name
- NCT06974643
- Testing
- Thoracic epidural block, Paravertebral block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Colorectal Cancer
Inflammatory Response After Colorectal Cancer Surgery
Laparoscopic technique and epidural anesthesia have been proposed to improve postoperative outcome following colorectal cancer surgery.
- Trial name
- CRC (NCT01427647)
- Testing
- Laparoscopic technique and thoracic epidural anesthesia
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Universidad Complutense de Madrid
Thoracic Surgery
Continuous Erector Spinae Block Versus Thoracic Epidural Analgesia for the Prevention of Chronic Pain Following Thoracotomy: a Retrospective Study
Post-thoracotomy pain syndrome (PTPS) is a prevalent complication that significantly impacts patients' quality of life, with reported incidence ranging from 25% to 90%.
- Trial name
- NCT07677540
- Testing
- ESP block, Thoracic epidural
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Meir Medical Center
Total Knee Anthroplasty, Epidural Analgesia
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty
The goal of this clinical trial is to compare two different epidural analgesia delivery methods for pain control after total knee arthroplasty in adults undergoing elective surgery.
- Trial name
- NCT07605208
- Testing
- Programmed intermittent epidural bolus 6 ml, continuous epidural infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Epidural Anesthesia, Catheterisation
Epidural Catheter Placement Techniques by Anesthesia Residents: Success and Complications
This prospective observational study aims to evaluate the impact of epidural catheter placement techniques - loss of resistance (LOR) and hanging drop (HD) - on first-attempt success rates and procedural complications among…
- Conditions
- Epidural Anesthesia, Catheterisation, Education, Postoperative Pain
- Trial name
- EPİ-TECH (NCT07573007)
- Testing
- epidural catheter placement
- Where
- Turkey (Türkiye)
- Volunteers
- 440 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Anesthesia, Hernia, Inguinal
Comparative Study Between US Guided Erector Spinae and US Guided Cudal Epidural Block
Inguinal hernia is a common condition requiring surgical repair in the pediatric age group. The incidence of inguinal hernias is approximately 3% to 5% in term infants and 13% in infants born at less than 33 weeks of gestational…
- Trial name
- NCT07127601
- Testing
- Ultrasound guided erector spinae plain block (ESPB).
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cancer of Pancreas
Effects of Epidural Block on the Prognosis in Patients With Pancreatic Cancer Undergoing Distal Pancreatectomy
The purpose of this randomized controlled clinical trial is to investigate the effects of epidural block on overall survival，disease-free survival and recovery in patients with pancreatic cancer undergoing distal pancreatectomy.
- Trial name
- NCT03659292
- Testing
- GEA, PCEA, GA
- Where
- 3 sites in China
- Volunteers
- 540 people
- Sponsor
- Fudan University
Pain, Postoperative, Osteoarthritis
Pain Treatment After Total Knee Replacement - Continuous Epidural Versus Intravenous Patient Controlled Analgesia With Morphine
The study purpose is to compare the effectiveness of different methods for post-operative pain treatment after total knee replacement.
- Trial name
- NCT00270322
- Testing
- Marcaine 0.166% + Fentanyl 3.33 mcg/ml, Morphine sulphate
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rambam Health Care Campus
Gynecologic Disease Requiring Laparoscopic Hysterectomy Under Neuraxial Anesthesia
Dural Puncture Epidural Technique Versus Conventional Epidural Techmique
This study will be conducted on 50 patients of ASA grade I and II aged from 25 to 55 years and presented for laparoscopic hysterectomy.
- Trial name
- NCT05032677
- Testing
- Conventional Epidural Technique, Dural Puncture Epidural Technique using pencil-point 25G Whitacre needle
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obstetric Pain, Anesthesia, Local
Obstetric Placement Study Using EST
Combined spinal-epidural (CSE) is an established technique for providing labour analgesia to obstetric patients which provides rapid onset but unsustained analgesia.
- Trial name
- NCT04109365
- Testing
- Electrical Epidural Stimulation Test (EST)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University