Clinical trials: Epidural/Anesthesia
Labor Pain
Parturient Controlled Epidural Analgesia (PCEA) With or Without a Basal Infusion for Early Labor
Patient Controlled Epidural Analgesia is a widely used and effective means of adult pain management. However, Parturient Controlled Epidural Analgesia (PCEA) is a relatively new approach to pain control for the women in labor.
- Trial name
- NCT00871442
- Testing
- No Basal Infusion, Basal infusion, PCEA solution (bupivacaine and fentanyl)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neil Roy Connelly, MD
Malignant Neoplasm of Abdomen, Surgery
TAP Versus Thoracic Epidural in Major Abdominal Resections
The purpose of this study is to compare two standard methods of pain control management used at Spectrum Health for patients undergoing major surgery. The two methods being compared are the thoracic epidural and the TAP block.
- Trial name
- NCT02197988
- Testing
- Exparel 1.33% (20ml Volume), 0.125% bupivicaine with 2 mcg/ml Fentanyl.
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Corewell Health West
Pain, Thoracotomy
Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After Thoracotomy
Objective: Epidural analgesia is the gold standard for post-thoracotomy pain relief but is contraindicated in certain patients. An alternative is continuous wound catheter analgesia.
- Trial name
- NCT01698203
- Testing
- ropivacaine 0.75% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun), ropivacaine 0.2% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun)
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Strasbourg, France
Anesthesia, Epidural, Analgesia, Epidural
Comparison of Skin - Epidural and Intervertebral Distances in Sitting and Rider Position
Epidural anesthesia/analgesia can be performed under various positions. In this study, the investigators aimed to compare the intervertebral and skin-epidural distances in "the sitting" and "rider" positions with the help of…
- Conditions
- Anesthesia, Epidural, Analgesia, Epidural, Ultrasound Imaging
- Trial name
- NCT05642234
- Testing
- Epidural Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Labor Analgesia, Labor Pain
Effect of Dural Puncture Epidural Analgesia on Oxytocin in Early vs Late Labor
Oxytocin is a key hormone that regulates uterine contractions during labor. Dural Puncture Epidural Analgesia (DPEA) is a modern technique for labor pain relief that provides faster onset and more reliable analgesia than standard…
- Conditions
- Labor Analgesia, Labor Pain, Oxytocin
- Trial name
- DPEA-OXY (NCT07873814)
- Testing
- Dural Puncture Epidural Analgesia (DPEA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Elective Major Abdominal Surgery
Postoperative Analgesia of Quadratus Lumborum Block Versus Epidural Block After Major Abdominal Surgeries
Acute postoperative pain is an important issue after major abdominal surgeries for which different analgesic modalities have been tried.
- Trial name
- NCT04541732
- Testing
- Thoracic epidural block, Ultrasound-guided bilateral quadratus lumborum block, Induction of general anaesthesia with propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Acute Pancreatitis
Epidural Anesthesia in Acute Pancreatitis
Acute pancreatitis is a common urgency with a mortality rate of up to 30% , decreased blood flow in the pancreatic microcirculation. It seems to be the main cause of the pathophysiology of acute pancreatitis.
- Trial name
- NCT02617199
- Testing
- Epidural anesthesia, intravenous analgesia
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital General Naval de Alta Especialidad - Escuela Medico Naval
Pregnancy Related
Optimizing Anesthesia for Post Partum Tubal Ligations
In this study, the investigators will compare CLOROTEKAL® (1% spinal chloroprocaine) to low-dose isobaric bupivacaine using the epidural volume extension (EVE) technique in patients undergoing post-partum tubal ligation (PPBTL).
- Trial name
- NCT03993314
- Testing
- Chloroprocaine, Bupivacaine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pregnant Women Who Requested Epidural Analgesia in the Early Stage of Labor
Onset of Labour Epidural Analgesia With Different Concentration Bupivacaine and Different Doses of Sufentanyl
This study aimed to compare the effects of three commonly used combination doses on the onset time and adverse reactions.
- Trial name
- NCT03395600
- Testing
- B1S5, B125S5, B1S10
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Fudan University
Labor Analgesia
Handheld Ultrasound-assisted Versus Palpation-guided Labor Combined Spinal-epidural Analgesia
Parturients who need combined spinal-epidural analgesia for labour analgesia are randomly assigned to two groups. For the handheld ultrasound-assisted technique group, ultrasound with 3D navigation function is used to determine…
- Trial name
- NCT04759547
- Testing
- handheld ultrasound-assisted technique, conventional palpation-guided technique
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative Pain
EXORA Block vs Epidural Analgesia in Gynecological Surgery
This prospective observational study aims to compare the effects of the EXORA block and epidural analgesia on postoperative pain control and quality of recovery in patients undergoing gynecological surgery.
- Trial name
- NCT07346872
- Testing
- Tramadol, exora block, epidural
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Anesthesia, Anesthesia Recovery Period
Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Unilateral Nephrectomy.
Different modality of anesthesia and analgesia could influence a postoperative quality of recovery (QoR). This study is exploring early QoR after unilateral nephrectomy in the two groups of anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Nephrectomy, Patient Satisfaction
- Trial name
- QoR (NCT04521556)
- Testing
- Epidural anesthesia with light general anesthesia, Postoperative epidural analgesia, General anesthesia
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- University Hospital of Split
Analgesia, Epidural
Auriculotherapy for Prevention of Postoperative Urinary Retention
Urinary retention is a common complication of epidural analgesia. Auriculotherapy could prevent this complication. This study will be performed among men receiving thoracic epidural analgesia after thoracic surgery.
- Trial name
- RUPO (NCT02290054)
- Testing
- Control, Treated, Intra-venous anesthesia
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Hopital Foch
Anesthesia, Epidural, Analgesia, Epidural
"Compuflo®" in Epidural Space Identification
Recently a computerized injection pump has been programmed with its own mathematical algorithm to measure on a digital display the pressure trend in the form of a continuous curve and it has been connected to an acoustic device…
- Trial name
- NCT03503656
- Testing
- epidural catheter placement
- Volunteers
- 140 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Postoperative Pain After Cesarean Section
Comparison of Combined Spinal Epidural Analgesia and Erector Spinae Plane Block After Elective Cesarean Section
Postoperative pain after cesarean section can significantly affect maternal recovery, early mobilization, and patient satisfaction.
- Trial name
- CSEA-ESP-CS (NCT07411521)
- Testing
- Combined Spinal Epidural Analgesia, Ultrasound-Guided Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Myocardial Ischemia, Autonomic Neuropathy
Coronary Blood Flow Regulation During General Anesthesia
The central hypothesis in the present project is that general anesthesia may alter autonomic control such that perioperative coronary blood flow (CBF) is significantly disturbed.
- Conditions
- Myocardial Ischemia, Autonomic Neuropathy, Healthy, Diabetes
- Trial name
- NCT00866801
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Labor Pain
The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia
The purpose of this study is to determine the ideal dosage of intrathecal morphine for intra and post partum analgesia, while minimizing the side effect profile.
- Trial name
- NCT01146457
- Testing
- Morphine, Saline
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Beth Israel Deaconess Medical Center
Acute Pancreatitis
The Application of Thoracic Epidural Analgesia in Patients With Acute Pancreatitis
Acute pancreatitis (AP) is one of the most common diseases of the digestive system, with its incidence increasing year by year. 15%-25% of patients will develop severe acute pancreatitis (SAP), characterized by necrosis and…
- Trial name
- NCT06327230
- Testing
- Thoracic Epidural Analgesia
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Sir Run Run Shaw Hospital
Pain, Postoperative
Continuous Thoracic Epidural Versus Erector Spinae Plane Block for Postoperative Analgesia in Donar Hepatectomies.
Introduction Adult living related donor hepatectomy is associated with pain due to the sub-costal j-shaped incision, rib retraction using Thompson retractor, and diaphragm irritation1.
- Trial name
- NCT04151511
- Testing
- Continuous Erector Spinae Plane Block
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa Clinical Research Center
Difficulty Processing Information
Impact of a Video Explaining Epidural Analgesia in Obstetrics
The aim of this study was to investigate the impact of multimedia information on epidural anesthesia. Pregnant women were randomly assessed to get a video information in addition to an oral and written information on epidural…
- Trial name
- VIDEOCLIP (NCT02899806)
- Testing
- Written Information, Video Information
- Where
- France
- Volunteers
- 301 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil