Clinical trials: Epidural/Anesthesia
Post Operative Pain, Acute, Chronic Post Surgical Pain
Continuous Epidural With Dexmedetomidine Adjuvant in Gynecologic Laparotomy
The goal of this clinical trial is to learn if adding a medication called dexmedetomidine to an epidural block works better than a standard epidural to control pain in women undergoing gynecologic laparotomy (abdominal surgery).
- Conditions
- Post Operative Pain, Acute, Chronic Post Surgical Pain, Gynecologic Disease
- Trial name
- NCT07292324
- Testing
- Dexmedetomidine & Bupivacaine., Bupivacain
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Udayana University
Preoperative Warming, Prewarming
Preoperative Patient Warming for Prevention of Perioperative Hypothermia in Major Abdominal Surgery
The study should evaluate how long patients undergoing major abdominal surgery under combined general/epidural anaesthesia have to be actively warmed preoperatively to prevent perioperative hypothermia and postoperative…
- Conditions
- Preoperative Warming, Prewarming, Perioperative Hypothermia, General Anaesthesia
- Trial name
- THER-6 (NCT01795482)
- Testing
- Forced-air warming
- Where
- 2 sites in Germany
- Volunteers
- 99 people
- Sponsor
- University Hospital Schleswig-Holstein
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Leg Elevation for Prevention of Post Spinal Hypotension in Cesarean Section
Prospective trial including full term parturients scheduled for a cesarean section under spinal anesthesia. patients are being randomly assigned into 2 groups: LE group: will be positioned in 15° left tilt with leg elevation with…
- Trial name
- NCT03488277
- Testing
- leg elevation
- Where
- Tunisia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Aortic Aneurysm, Postoperative Nausea and Vomiting
AoA Guided Thoracic Epidural Analgesia for Abdominal Aortic Repair
The aim of this randomized trial is to assess the efficacy of analgesia using either thoracic epidural or intravenous infusions for open lumbar infrarenal aortic aneurys repair and compare Numerical Rating Scale (NRS) with…
- Conditions
- Aortic Aneurysm, Postoperative Nausea and Vomiting, Postoperative Pain, Haemodynamic Stability
- Trial name
- AoA-AAA (NCT06609993)
- Testing
- intravenous rescue opioid analgesia using fentanyl, intravenous rescue atropine administration, intravenous rescue urapidil administration
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Michał Stasiowski
Caudal Epidural Block, Coccygodynia
Efficacy of Combining Caudal Epidural Steroid With Ganglion Impar Block in Chronic Coccydynia
Coccydynia refers to pain localized to the tailbone (coccygeal) region. Initial management is conservative-nonsteroidal anti-inflammatory drugs (NSAIDs), use of a seat cushion, and physical therapy-yet a proportion of patients…
- Conditions
- Caudal Epidural Block, Coccygodynia, Coccydynia
- Trial name
- NCT07200765
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Mersin University
Surgical Pain
Erector Spinae Plane Block Versus Caudal Epidural Analgesia
The goal of this clinical trial is to compare the analgesic effect and safety of erector spinae plane block vs caudal epidural block in paediatric population undergoing lower limb cancer surgery.
- Trial name
- NCT06815094
- Testing
- Regional analgesia either CEA or ESP
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- National Cancer Institute, Egypt
Colon Cancer, Rectal Cancer
Compare Preperitoneal Analgesia to Epidural Analgesia for Pain Control After Colon and Rectal Surgery
This is a prospective randomized study of 114 patients. The purpose of this study is to compare the efficacy of two standard methods of analgesia for pain control in patients undergoing elective colon and rectal surgery, as…
- Conditions
- Colon Cancer, Rectal Cancer, Colonic Diverticulosis
- Trial name
- NCT01552226
- Testing
- Continuous Preperitoneal Analgesia, Continuous Epidural Analgesia
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Trinity Health Michigan
Laboring Women
The Effect of the Use of Peanut Ball on Labor Time in Nulliparous Women
Peanut ball use has become popular with midwives and nurses because it is an inexpensive, nonpharmacological intervention that can help with positioning the patient to decrease labor time.
- Trial name
- NCT04998149
- Testing
- Peanut Ball positioning device
- Where
- 4 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Epidural Anesthesia, Ropivacaine Concentration
Effects of Epidurally Administered Ropivacaine Concentration on the Hemodynamic Parameters
In this trial, the investigators intend to examine whether the concentration of local anesthetics during epidural analgesia could be modulating factor for change of hemodynamics in patients undergoing major upper abdominal…
- Conditions
- Epidural Anesthesia, Ropivacaine Concentration, Hemodynamics
- Trial name
- PNU (NCT01559285)
- Testing
- 0.75% ropivacaine concentration, 0.375% ropivacaine concentration, 0.2% ropivacaine concentration
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Pusan National University Hospital
Epidural Analgesia for Labour and Delivery
Cross-legged Versus Traditional Sitting Position for the Success of Epidural Analgesia During Labor
The success of an epidural analgesia catheter placement depends on the parturient position. A poor posture can increase the number of punctures, patient discomfort, and risk of complications.
- Trial name
- IP3 (NCT04754282)
- Testing
- Position of labouring women for epidural analgesia catheter placement : Traditional Sitting Position (TSP), Position of labouring women for epidural analgesia catheter placement : Cross-legged Sitting Position (CSP)
- Where
- France
- Volunteers
- 457 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Labor Pain
Differential Sensory Block During Labor Epidural Analgesia: a Prospective Observational Study to Investigate the Relationship of Lower and Upper Sensory Block Levels to Cold With Sensory Block to Pinprick and Light Touch
Epidural analgesia remains the gold standard for pain control during labor and delivery. Proper assessment of an epidural's level of blockade is important for providing safe and effective analgesia.
- Trial name
- NCT05187962
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Flail Chest
Thoracic Epidural Analgesia in Flail Chest
The applicability of different thoracic epidural analgesia for patients with flail chest
- Trial name
- NCT03413059
- Testing
- Morphine Sulfate, Triamcinolone Acetonide
- Volunteers
- 40 people
- Sponsor
- Assiut University
Gall Stone Disease, Polyp
Combined Spinal Epidural Anesthesia and General Anesthesia for Laparoscopic Cholecystectomy
The aim of this study was to compare general anesthesia (GA) and combined (epidural and spinal) anesthesia (CA) for laparoscopic cholecystectomy. General anesthesia is a gold standard for laparoscopic cholecystectomy(LC).
- Trial name
- NCT02317510
- Testing
- combined anesthesia, general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Pain, Acute
Programmed Intermittent Bolus Dosing Versus Continuous Epidural Infusion for Epidural Analgesia in Abdominal Surgery.
Epidurals are an effective means for providing neuraxial anesthesia and analgesia. Prior studies in labor epidurals have demonstrated that a programmed intermittent bolus application of local anesthesia can improve pain control…
- Trial name
- NCT03307174
- Testing
- Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Total Knee Replacement, Optic Nerve Sheath Diameter Measurement
The Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter Measurements in Total Knee Prosthesis Surgery
This study investigates the effects of epidural anesthesia on intracranial pressure (ICP) by using ultrasonographic optic nerve sheath diameter (ONSD) measurements as a non-invasive indicator.
- Conditions
- Total Knee Replacement, Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Change
- Trial name
- NCT07458321
- Testing
- Bupivacaine %0.25 (isobaric), Bupivacaine %0.5 (hyperbaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Low Back Pain Due to Spinal Nerve Compression
Determination of a Proper Needle Entry Point; Effects of Skin Compression With an Indicator on Radiation Exposure Time of Fluoroscopically Guided Transforaminal Epidural Block in Obese Patients
To evaluate the effects of skin compression with an indicator at the needle entry point on radiation exposure time of fluoroscopically guided transforaminal epidural block in obese patients
- Trial name
- NCT02281227
- Testing
- skin compression
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Rib Fractures
Non-Inferiority Study of Erector Spinae Plane Block Compared to Thoracic Epidural in Pain Management of Rib Fractures
The purpose of this study is to compare 2 pain control treatments for people with 3 or more rib fractures.
- Trial name
- SUETHE-Ribs (NCT05069961)
- Testing
- ESPB, TEA
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Gastric Cancer
Comparison of the Effects of Continuous Epidural Analgesia and Continuous Intravenous Analgesia on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy
The investigators hypothesized that sympatholytic effect of epidural analgesia would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery.
- Trial name
- NCT02458573
- Testing
- continuous epidural analgesia, continuous intravenous analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Yonsei University
Labor, Obstetric
Nutrition as a Determinant of Labor Outcome
This is a randomized, double-blind trial looking at how nutrition intake is associated with labor progress and complications.
- Trial name
- NCT00367549
- Testing
- Energy-containing soft drink
- Where
- Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Pain
Comparison of Patient Controlled & Continuous Epidural Analgesia in Thoraco-abdominal Surgeries in Cancer Patients
This study aims to compare the efficacy of pain control, the consumption of local anesthetic and opioids, side effects, and patient satisfaction between continuous epidural infusion and patient controlled epidural analgesia after…
- Trial name
- NCT02803385
- Testing
- Continous Epidural Analgesia, Patient Controlled Epidural Analgesia
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Tata Memorial Centre