Clinical trials: Epidural/Anesthesia
Analgesia
Rivanna Ultrasound for Neuraxial Block
We hypothesize that the Rivanna Accuro or similar U/S device would reduce time to success of identifying epidural and/or intrathecal spaces as compared to conventional palpation method.
- Trial name
- NCT03214640
- Testing
- Rivanna Accuro US Device, Palpation, Neuraxial Analgesia
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Wake Forest University Health Sciences
Obesity, Pregnancy Related
Combined Spinal Epidural Anesthesia in Obese Patients Undergoing Cesarean Surgery
This study investigated the maternal and fetal effects during performance of CSEA in the left lateral decubitus and sitting positions in obese pregnant women undergoing elective cesarean section.
- Conditions
- Obesity, Pregnancy Related, Cesarean Section Complications, Spinal Anaesthetic Poisoning of Undetermined Intent
- Trial name
- NCT04612998
- Testing
- left lateral decubitus position, sitting position, The use of intravenous ephedrine.
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Coronary Artery Bypass, Epidural Anesthesia
Comparison of Ropivacaine and Levobupivacaine in High Thoracic Epidural Anesthesia
In High Thoracic Epidural Anesthesia (HTEA) the use of a local anesthetic (LA) with low cardiac toxicity is crucial as myocardial contractility is often already seriously impaired.
- Trial name
- NCT00552864
- Testing
- Ropivacaine, Levobupivacaine
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Centro Cardiologico Monzino
İnguinal Hernia
Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Caudal Epidural Block
The goal of This prospective, randomized, double-blind comparative study is to compare the efficacy of dexamethasone and dexmedetomidine as adjuvants to bupivacaine 0.125% in caudal epidural block for pediatrics undergoing…
- Trial name
- NCT07056244
- Testing
- Dexmedetomidine, Dexamethasone
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
Labor Pain
A Comparison of Epidural Analgesia: Continuous Infusion Versus Programmed Intermittent Boluses
The analgesic approach in labor can be done in different ways, among which the neuraxial approach has shown the best analgesic results and fetal outcomes.
- Trial name
- NCT02510287
- Testing
- Bupivacaine and Fentanyl Initial Dose, Bupivacaine and Fentanyl: Continuous Epidural Infusion, Bupivacaine and Fentanyl: Programmed Intermittent Epidural Bolus
- Where
- Colombia
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
THoracotomy
Extrapleural Intercostal Catheter vs. Thoracic Epidural for Thoracotomy Pain
We will compare thoracic epidural anesthesia which is presently used for management of pain after thoracotomy to an intra-operatively placed extrapleural intercostal catheter. The study wil be double blinded and prospective.
- Trial name
- NCT00373633
- Testing
- Thoracic Epidural, Extrapleural Intercostal Catheter
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Virginia Commonwealth University
Organ Dysfunction, Organ Support
Thoracic Epidural Analgesia for Acute Pancreatitis With Early Organ Dysfunction
Acute pancreatitis may cause early respiratory, cardiovascular, or renal dysfunction and may require intensive care and organ support.
- Conditions
- Organ Dysfunction, Organ Support, Acute Pancreatitis (AP)
- Trial name
- TEA-APOD (NCT07697690)
- Testing
- Thoracic Epidural Analgesia With Ropivacaine, conventional analgesia
- Volunteers
- 150 people
- Sponsor
- First People's Hospital of Chenzhou
Labor Pain
Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural
Neuraxial analgesia has shown to be the gold standard for effective labor pain relief, offering numerous benefits including enhanced pain control and maternal satisfaction.
- Trial name
- NCT06572241
- Testing
- Intrathecal morphine
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
HoLEP, QoR-40
Effect of Anesthesia Techniques on Quality of Recovery Scores in HOLEP Surgery
The aim of this observational study is to evaluate the effects of different anesthesia techniques on the quality of recovery (QoR) and patient satisfaction in male patients, typically older adults with benign prostatic…
- Conditions
- HoLEP, QoR-40, Anesthesia, General, Anesthesia,Spinal
- Trial name
- NCT07020390
- Testing
- Anesthesia method
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- TC Erciyes University
Osteoarthritis of the Knee
Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain, causing patient discomfort, mobilisation and hospital discharge. The aim of this study is to: 1.
- Trial name
- NCT00562627
- Testing
- ropivacaine, adrenaline, ketorolac
- Where
- Norway
- Volunteers
- 102 people
- Sponsor
- Asker & Baerum Hospital
Elective Cesarean Section
Influence of Surgical Regional Anesthesia on Postoperative Pain
To compare three Types of anesthetic techniques (Spinal anesthesia, Combined spinal epidural anesthesia, Combined spinal epidural anesthesia with indwelling catheter for 24 hrs) on pain after elective cesarean section.
- Trial name
- CESAR (NCT01234662)
- Testing
- SPA, CSE, CSEPCEA
- Where
- Germany
- Volunteers
- 171 people
- Sponsor
- Charite University, Berlin, Germany
Stress Response, Hemodynamic Changes
Stress Response and Hemodynamic Changes Associated With Intrathecal Anesthesia Versus Caudal Epidural Anesthesia in Infants Undergoing Laparoscopic Inguinal Herniorrhaphy
The aim of this work was to assess stress response and hemodynamic changes associated with intrathecal anesthesia versus caudal epidural anesthesia in infants undergoing laparoscopic inguinal herniorrhaphy.
- Conditions
- Stress Response, Hemodynamic Changes, Intrathecal Anesthesia, Caudal Epidural Anesthesia
- Trial name
- NCT06909396
- Testing
- General anesthesia, Intrathecal Anesthesia, Caudal block
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Intubation Skill, Laryngeal Mask Airway Insertion Skill
Evaluation of Learning Curve of Manual Skills in Anesthesia Residents
To determine number of cases need to perform in new anesthesia residents to be proficient in manual skills.
- Conditions
- Intubation Skill, Laryngeal Mask Airway Insertion Skill, Spinal Anesthesia Skill, Epidural Anesthesia Skill
- Trial name
- NCT01236183
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Anesthesia
Segmental Epidural Block for Feeding Jeujunostomy in Cancer Patients
This study aim is to compare the efficiency and safety of segmental epidural block versus general anesthesia in cancer patients undergoing surgical feeding jejunostomy
- Trial name
- NCT04376086
- Testing
- Epidural anesthesia, general anesthesia
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Cancer Institute, Egypt
Anesthesia, Epidural, Breast Feeding
Intrapartum Epidural Fentanyl/Bupivacaine Analgesia, Infant Feeding Behavior, & Breast-Feeding Outcomes
Currently, no clear consensus exists regarding the effect of epidural anesthesia upon breast-feeding. In theory, epidurals may increase breast-feeding failure via inadequate maternal milk production, deficiencies in neonatal…
- Trial name
- NCT01260051
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- University Hospitals Cleveland Medical Center
Esophagectomy, Epidural; Anesthesia
Erasme Randomized Controlled Trial Surveys Hemodynamic Excursions During Esophagectomy
In our high volume center, the majority of esophagectomy procedures are performed with minimally invasive techniques. The thoracic epidural technique remains the gold standard and homolateral paravertebral catheter is strongly…
- Conditions
- Esophagectomy, Epidural; Anesthesia, Paravertebral Anesthesia, Hemodynamic Instability
- Trial name
- ERASME ULB (NCT06563557)
- Testing
- Hemodynamic changes between epidural and paravertebral during esophagectomy
- Volunteers
- 75 people
- Sponsor
- Erasme University Hospital
Epidural; Anesthesia, Headache
Epidural Anesthesia and Myomectomy Associated Bleeding
This is a prospective study for abdominal myomectomies performed from June 2012 to June 2019 by a single surgeon in a tertiary care referral hospital.
- Trial name
- NCT04629573
- Testing
- Lumber Epidural, General anesthesia
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Assiut University
Analgesia
The Effect of Combined Spinal Epidural Anaesthesia on QTc Interval Undergoing Cesarean Section
Cesarean section is the operation to deliver the fetus, placenta and membranes by making an abdominal incision in the uterus. Cesarean section is performed for reasons such as head-pelvis incompatibility, fetal malposition, fetal…
- Trial name
- NCT06018805
- Testing
- BMI≥30; Combined Spinal Epidural Anesthesia, BMI:18,5-24,9; Combined Spinal Epidural Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Labor Pain
Combined Spinal/Epidural (CSE) Saline Duration/Spread
An attempt is being made to see if by injecting a set volume of sterile saline into the epidural space during the treatment of labor pain with a combined spinal/epidural (CSE) increases the amount of pain relief obtained and…
- Trial name
- NCT01062893
- Testing
- Sterile normal saline 0 mls, 15 mls sterile normal saline
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Wake Forest University Health Sciences
Labor Pain
Intrathecal Clonidine Addiction for Combined Spinal Epidural Analgesia During Labor
The study aims to evaluate the impact of the addition of 20 mcg of intrathecal clonidine in combined spinalepidural for labor analgesia on the local anesthetic consumption, on labor performance and on maternal fetal well-being.
- Trial name
- ICA (NCT03018171)
- Testing
- Clonidine, Sufentanil
- Where
- Italy
- Volunteers
- 268 people
- Sponsor
- San Giovanni Calibita Fatebenefratelli Hospital