Clinical trials: Epidural
Radiculopathy, Lower Extremity Radicular Pain
Somatosensory Profiling in Radicular Pain Patients And it's Correlation With Treatment Outcome
The investigators hypothesize that there may exist different quantitative sensory profiles between radicular pain patients who respond and those who do not respond to the standard therapy of epidural steroid injections (ESI).
- Trial name
- NCT02130258
- Testing
- Quantitative Sensory Testing (QST), Epidural Steroid Injection (ESI)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Massachusetts General Hospital
Spastic Cerebral Palsy
Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children
The purpose of this proposal is to improve the investigators' current Selective Dorsal Rhizotomy (SDR) analgesia protocol by eliminating or minimizing the use of fentanyl in the post-operative period.
- Trial name
- NCT00955877
- Testing
- Extended-release Epidural morphine (EREM) 80, Extended-release Epidural Morphine (EREM) 120, Control: Saline
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Cervical Radiculopathy
Comparative Trial Via Tranforaminal Approach Versus Epidural Catheter Via Interlaminar Approach
Do cervical epidural steroid injections done by transforaminal catheter targeted approach improve pain and function in patients with cervical radicular pain?
- Trial name
- NCT03382821
- Testing
- Transforaminal ESI with dexamethasone, Transforaminal catheter-targeted ESI with triamcinolone, Dexamethasone Sodium Phosphate 10 MG/ML
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Utah
Pain
Epidural Morphine Following Vaginal Delivery
The investigators believe that pain management following a vaginal delivery can be improved. Many women receive epidural medication during labor and delivery, and the investigators felt that using the epidural following delivery…
- Trial name
- NCT00803114
- Testing
- Preservative-free epidural morphine
- Where
- Canada
- Volunteers
- 228 people
- Sponsor
- Mount Sinai Hospital, Canada
Cervicogenic Upper Extremity Radiculopathy
Transforaminal Versus Lateralized Interlaminar Cervical Epidurals
The purpose of this study is to compare two methods of giving epidural steroid injections for nerve pain in the arm that comes from the neck.
- Trial name
- NCT03389620
- Testing
- dexamethasone
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Duke University
Epidural Spinal Tumors, Cancer
Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab
The purpose of this research study is to find out what effects (good and bad) Pembrolizumab and radiosurgery have on participants with high-grade epidural disease of the spine.
- Trial name
- NCT05204290
- Testing
- Pembrolizumab, Stereotactic Body Radiation Therapy, Blood draws
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Wake Forest University Health Sciences
Satisfaction
Music During Labor Epidural Placement and Patient Satisfaction
Patient satisfaction is becoming increasingly important to hospital administrators as a metric for quality of patient care services because it is now being linked to reimbursements (Maher 2015).
- Trial name
- NCT02734056
- Testing
- Music, Control
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Bilateral Transforaminal Epidural Steroid Injections for Degenerative Lumbar Spinal Stenosis
The most common forms of injection used for the treatment of degenerative lumbar spinal stenosis (DLSS) patients with neurogenic claudication (NC) are the caudal and inter-laminar epidural injections of anesthetic and steroid.
- Trial name
- NCT01995461
- Testing
- bilateral transforaminal epidural steroid injections
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Marshfield Clinic Research Foundation
Cerebrospinal Fluid Leaks
A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment
The goal of this randomized controlled trial (RCT) is to compare the efficacy of CT fluoroscopy-guided targeted epidural patching for treatment of imaging-confirmed spinal CSF leaks to that of a simulated procedure without…
- Trial name
- NCT03276975
- Testing
- TISSEEL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Obstetric Pain
Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
During labor there is an increased production of inflammatory mediators called cytokines. Higher concentration of certain cytokines has been linked to adverse neonatal and maternal outcomes.
- Trial name
- NCT00361712
- Testing
- Preemptive epidural analgesia, Standard of care
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Lumbar Spinal Stenosis
Epidural Lavage Study for Lumbar Stenosis
The purpose of this research is to find out if there are inflammatory biomarkers (also known as biological markers) in epidural space that can predict response to an epidural steroid injection.
- Trial name
- NCT03511053
- Testing
- Epidural Steroid Injection with Lavage
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Dallas VA Medical Center
Pain, Morphine Adverse Reaction
Two Dose Epidural Morphine for Post-cesarean Analgesia
The investigators aim to assess the analgesic effect of a two-dose epidural morphine regimen for 2nd day post-cesarean pain, as part of a multimodal analgesia regimen, which includes scheduled Nonsteroidal anti-inflammatory drugs…
- Trial name
- NCT01844206
- Testing
- Epidural Morphine, Epidural Saline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Intraoperative Complication, Malignant Female Reproductive System Neoplasm
Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery
This randomized clinical trial studies epidural anesthesia within an enhanced recovery pathway (ERP) in reducing pain in patients undergoing gynecologic surgery.
- Conditions
- Intraoperative Complication, Malignant Female Reproductive System Neoplasm, Pain
- Trial name
- NCT02423876
- Testing
- Epidural analgesia, Intraoperative Complication Management and Prevention, Pain Therapy
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Wisconsin, Madison
Pain Management Strategies in Liver Resection Surgery
TEA vs. PVB vs. PCA in Liver Resection Surgery
This study aims to compare the efficacy and safety of three alternative methods of analgesia in patients undergoing complex liver resection surgery: 1) thoracic epidural analgesia (TEA), 2) continuous paravertebral block (PVB)…
- Trial name
- NCT02192879
- Testing
- thoracic epidural, continuous paravertebral catheter, Patient-Controlled Analgesia
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Cesarean Section
A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus
The purpose of this study is to determine if epidural meperidine administered by patient-controlled bolus button is equivalent to a low dose infusion plus patient-controlled bolus.
- Trial name
- NCT01741259
- Testing
- Meperidine
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Mercy Research
Colon Cancer, Rectal Cancer
Compare Preperitoneal Analgesia to Epidural Analgesia for Pain Control After Colon and Rectal Surgery
This is a prospective randomized study of 114 patients. The purpose of this study is to compare the efficacy of two standard methods of analgesia for pain control in patients undergoing elective colon and rectal surgery, as…
- Conditions
- Colon Cancer, Rectal Cancer, Colonic Diverticulosis
- Trial name
- NCT01552226
- Testing
- Continuous Preperitoneal Analgesia, Continuous Epidural Analgesia
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Trinity Health Michigan
Liver Cancer, Pancreatic Cancer
Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient-Controlled Analgesia For Liver and/or Pancreas
The goal of this clinical research study is to learn if there is a difference in patients' quality of recovery if they receive 1 of 2 standard kinds of pain control treatments after surgery on the liver and/or pancreas.
- Trial name
- NCT01438476
- Testing
- Intravenous Patient-Controlled Analgesia (IVPCA), Thoracic Epidural Analgesia (TEA), Questionnaires
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- M.D. Anderson Cancer Center
Arrhythmia, Cardiac, Kidney Cancer
Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method
This study evaluates the incidence of cardiac arrhythmias during the perioperative period in patients undergoing open kidney cancer surgery in the lateral position.
- Conditions
- Arrhythmia, Cardiac, Kidney Cancer, Surgery, Anesthesia, Local
- Trial name
- NCT02988219
- Testing
- Bupivacaine-fentanyl, Holter ECG monitor, Open kidney cancer surgery
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Pain Following Thoracotomy Surgery
Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Unilateral intercostal nerve blocks provide pain control as effectively as a continuous thoracic epidural, and will a lower incidence of side effects.
- Trial name
- NCT02178553
- Testing
- Epidural, Intercostal Bupivicaine (Exparel)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mayo Clinic
Labor Pain, Analgesia
Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques
To estimate the dose of bupivacaine required to achieve initial effective comfort in 90% of patients (ED90) via the epidural (DPE or EPL) technique in women undergoing labor.
- Trial name
- NCT04814537
- Testing
- Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital