Clinical trials: Epidural, open to volunteers
Percutaneous Internal Ring Suturing, Pain Management
Comparison of the Postoperative Analgesic Effects of RSB and CEB in Pediatric Patients Scheduled for Percutaneous Internal Ring Suturing
Inguinal hernia is one of the most common surgical pathologies in children, and the minimally invasive percutaneous internal ring suturing (PIRS) technique is widely preferred.
- Trial name
- NCT07147062
- Testing
- Rectus Sheath Block, Caudal Epidural Block
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Total Knee Anthroplasty, Epidural Analgesia
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty
The goal of this clinical trial is to compare two different epidural analgesia delivery methods for pain control after total knee arthroplasty in adults undergoing elective surgery.
- Trial name
- NCT07605208
- Testing
- Programmed intermittent epidural bolus 6 ml, continuous epidural infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Thoracic Epidural Anesthesia, Paravertebral Block
Thoracic Epidural Anesthesia Versus Paravertebral Block for Awake Thoracotomy
This study aims to compare paravertebral block and thoracic epidural in awake thoracotomy.
- Conditions
- Thoracic Epidural Anesthesia, Paravertebral Block, Awake Thoracotomy
- Trial name
- NCT06974643
- Testing
- Thoracic epidural block, Paravertebral block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pregnant Women, Labor Pain
Neuraxial Labor Analgesia and Offspring Neurodevelopment
How perinatal factors affect the long-term development of children has always been an issue of much concern. This study is designed to explore the potential impact of maternal neuraxial labor analgesia exposure on offspring…
- Conditions
- Pregnant Women, Labor Pain, Analgesia, Epidural, Infants
- Trial name
- NCT04964206
- Testing
- Neuraxial labor analgesia, No neuraxial labor analgesia
- Where
- 2 sites in China
- Volunteers
- 4,645 people
- Sponsor
- Dong-Xin Wang
Posterior Fossa Epidural Hematoma
Predictors of Clinical and Neurological Outcome in Traumatic Posterior Fossa Epidural Hematoma
The posterior fossa is a small space in the skull containing the brainstem and cerebellum. If a mass such as a hemorrhage grows in this region, particularly the brainstem and 4th ventricle, it can block the normal flow of…
- Trial name
- NCT06847516
- Volunteers
- 94 people
- Sponsor
- Assiut University
Analgesia, Epidural
Comparison of Safety and Efficacy Between PIEB and CEI for Labour Epidural Analgesia
The goal of this clinical trial is to compare safety and efficacy of programmed intermittent epidural bolus (PEIB) and continuous epidural infusion (CEI) in parturients during active phase of labour.
- Trial name
- NCT06889285
- Testing
- Continuos epidural infusion, Programmed intermittent epidural bolus
- Where
- Malaysia
- Volunteers
- 76 people
- Sponsor
- Hospital Universiti Sains Malaysia
Epidural Analgesia, Ultrasound Assistance
Impact of Ultrasound Guidance on Central Neuraxial Block Success in Patients With Non-Palpable Vertebral Anatomy
Patients scheduled to undergo general surgery with planned epidural catheter placement will be evaluated by comparing two different techniques routinely used in anesthesia practice for catheter insertion.
- Trial name
- NCT07269184
- Testing
- epidural catheter, ultrasonography, anatomic landmark, epidural cateterisation
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Chronic Headache, Nutcracker Phenomenon, Renal
Lumbar Vein Embolization for Chronic Headaches With Nutcracker Physiology
The purpose of this research is to gather information on the safety and feasibility of coiling the lumbar vein for the treatment of chronic headaches in patients with Nutcracker physiology and retrograde lumbar vein flow with…
- Conditions
- Chronic Headache, Nutcracker Phenomenon, Renal, Nutcracker Syndrome, Renal
- Trial name
- NCT06077747
- Testing
- Coil Embolization of the Lumbar Vein
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mayo Clinic
Caudal Epidural Anesthesia, Sacral Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block for Postoperative Analgesia in Pediatric Patients Undergoing Orchiopexy: A Prospective Observational Study
This study aims to compare the analgesic efficacy of ultrasound-guided erector spinae plane block and caudal block for postoperative pain management in pediatric patients undergoing orchiopexy.
- Conditions
- Caudal Epidural Anesthesia, Sacral Erector Spinae Plane Block, Orchiopexy, FLACC Scale
- Trial name
- NCT07762339
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Brain Injuries, Respiratory Failure
Epidural Spinal Cord Stimulation for Respiratory Recovery in Brain Injury
Patients with severe brain injury may develop impaired respiratory drive, diaphragm dysfunction, prolonged mechanical ventilation, and difficulty recovering spontaneous breathing.
- Trial name
- BREATH (NCT07766681)
- Testing
- Epidural Electrode Implantation
- Where
- 3 sites in China
- Volunteers
- 10 people
- Sponsor
- Zhongda Hospital
Herniated Disc
Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain
The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications.
- Trial name
- NCT07036445
- Testing
- Epidural Steroid Injection, Epidural platelet-rich plasma injection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Spinal Cord Injuries (SCI)
Epidural Electrical Stimulation in Spinal Cord Injury
The goal of this clinical trial is to evaluate the safety and effectiveness of Epidural Electrical Stimulation (EES) in motor and sensory function Reconstruction in chronic spinal cord injury (SCI) patients classified as ASIA…
- Trial name
- NCT07105878
- Testing
- Epidural Electrical Stimulation, Standard Rehabilitation Therapy, positron emission tomography-computed tomography (PET-CT)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postpartum Recovery, Mother-infant Bonding
Labor Epidural Analgesia and Mother-Infant Bonding After Vaginal Delivery
This prospective observational cohort study aims to evaluate the association between postpartum recovery quality and mother-infant bonding in women undergoing vaginal delivery.
- Conditions
- Postpartum Recovery, Mother-infant Bonding, Labor Pain
- Trial name
- NCT07582289
- Testing
- Labor Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ataturk University
Pregnancy Complications, Atelectasis
Effect of Epidural Analgesia on Regional Lung Ventilation in Parturient Women as Assessed by Thoracic Impedance
The goal of this observational study is to learn more about the effect of obstetric epidural anesthesia on regional lung ventilation in healthy parturient women.
- Trial name
- NCT06195774
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital
Spinal Cord Injury Cervical, Respiratory Failure
Epidural Spinal Cord Stimulation for Respiratory Recovery in Cervical SCI
This multicenter, single-arm exploratory IIT evaluates epidural spinal cord electrical stimulation (ESCES) in 20 adults with C1-C5 SCI and respiratory failure.
- Trial name
- NCT07722130
- Testing
- Epidural spinal cord stimulation
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Zhongda Hospital
Anesthesia, Analgesia
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients.
- Trial name
- NCT05514431
- Testing
- Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Parturients, Accidental Puncture of Dura During Anaesthesia
Epidural Hydroxyethyl Starch for Post-Dural Puncture Headache in Parturients
The incidence of accidental dural puncture (ADP) among parturients receiving neuraxial labor analgesia has been reported to range from 1% to 1.5%.
- Conditions
- Parturients, Accidental Puncture of Dura During Anaesthesia, Epidural Filling, Hydroxyethyl Starch
- Trial name
- NCT07914790
- Testing
- Epidural hydroxyethyl starch, No epidural hydroxyethyl starch
- Where
- 4 sites in China
- Volunteers
- 410 people
- Sponsor
- Peking University First Hospital
Chronic Neck Pain, Cervical Radiculopathy
Cervical Epidural Block in Chronic Neck Pain
Chronic neck pain can negatively affect daily activities, work ability, and quality of life. Cervical epidural block is commonly used to reduce pain and inflammation, while exercise and physical therapy aim to improve muscle…
- Trial name
- CNP-TREAT (NCT07787741)
- Testing
- Cervical Epidural Steroid Injection, Cervical Stabilization Exercise Program, Physical Therapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Alİ Eman, MD
Spinal Cord Injury(SCI)
Exploration of the Effectiveness and Mechanism of Personalized Epidural Electrical Stimulation in Improving Upper Limb Function in Participants With Spinal Cord Injury
This study aimed to determine whether cervical spinal cord epidural electrical stimulation (EES) can activate upper-limb muscles in individuals with spinal cord injury.
- Trial name
- NCT07722429
- Testing
- Epidural electrical stimulation (EES)
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Thoracic Epidural
Effects of Fixation Technique On Thoracic Epidural Catheter Displacement
The purpose of our study is to assess the effectiveness of Dermabond as a thoracic epidural fixation technique compared to both Mastisol and the Grip-Lok fixation bandage, two common, widely used techniques for epidural fixation.
- Trial name
- NCT03976154
- Testing
- Thoracic Epidural Catheter Fixation Techniques
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Utah