Clinical trials: Epidural, active
Birth
Trial of Underwater Birth
Evaluate maternal perinatal outcomes in adult low-risk laboring people randomized to waterbirth compared to those randomized to birth on land.
- Trial name
- TUB (NCT07313319)
- Testing
- Waterbirth
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of New Mexico
Spinal Cord Injuries
Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury (BoxSwitch)
The purpose of this pre-market clinical study is to assess the preliminary safety and efficacy of the ARC Therapy using the ARC-IM Lumbar System at supporting mobility in participants who have previously received a spinal array…
- Trial name
- BoxSwitch (NCT05942339)
- Testing
- Procedure/Surgery
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Herniated Disc
Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain
The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications.
- Trial name
- NCT07036445
- Testing
- Epidural Steroid Injection, Epidural platelet-rich plasma injection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Analgesia Obstetrical, Analgesia
Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia
Cesarean section is one of the most commonly performed surgical procedures worldwide, making effective management of acute postoperative pain a key issue in obstetric anesthesiology.
- Conditions
- Analgesia Obstetrical, Analgesia, Post Operative Pain, Patient Satisfaction
- Trial name
- NCT07386353
- Testing
- Intrathecal Morphine, Epidural Morphine
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Thoracic Epidural Space Identification
Efficacy of CompuFlo® Technology in Thoracic Epidural Space Identification
The aim of this non inferiority trial is to assess the efficacy of CompuFlo® technology to identify the thoracic epidural space in relation to the gold standard loss of resistance technique.
- Trial name
- NCT05798754
- Testing
- Loss of resistance (LOR) technique, CompuFlo® technology
- Where
- Greece
- Volunteers
- 276 people
- Sponsor
- General and Maternity Hospital of Athens Elena Venizelou
Labour Pain
Spoken Animation for Labour Epidural
The purpose of this study is to evaluate a new animated information film as a tool for introducing the concept of epidural as a method of labour pain relief to expectant women.
- Trial name
- SALE (NCT07202221)
- Testing
- Participant views Epidural animation before reading gold standard written information, Participant receives current gold standard written information alone
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Blood Pressure, Low Back Pain
Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2)…
- Conditions
- Blood Pressure, Low Back Pain, Hypertension
- Trial name
- NCT05556902
- Testing
- Permanent Epidural Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Spinal Cord Injury, Spinal Cord Injury Thoracic
Investigating the Impact of Spinal Cord Electrical Stimulation Combined With Individualized Physical Therapy on Lower Extremity Function in Patients With Spinal Cord Injury
This study aims to understand the differences in the effects of two rehabilitation approaches on lower limb function recovery in patients with spinal cord injuries: 1.
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Thoracic, Spinal Cord Injury/Damage, Spinal Cord Injury T1-L2
- Trial name
- NCT07037628
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Lian-Cing Yan, MSPT
Caudal Epidural Anesthesia, Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block in Pediatric Patients Aged 1 to 8 Years Undergoing Lower Abdominal Surgery
In routine pediatric surgical practice, lower abdominal surgeries are commonly performed. Inadequate control of postoperative pain can hinder functional recovery and may lead to negative behavioral changes as well as parental…
- Conditions
- Caudal Epidural Anesthesia, Erector Spinae Plane Block, Pediatric
- Trial name
- NCT07426939
- Testing
- caudal block, Erector Spinae Plane Block
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Lumbar Disc Herniation, Lumbar Radiculopathy
PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation
This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD).
- Trial name
- PLDD-TFESI (NCT07400068)
- Testing
- Percutaneous Laser Disc Decompression (PLDD), Transforaminal Anterior Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Mersin University
Awake, Thoracic Epidural Anesthesia
Awake Thoracic Epidural Anesthesia Versus General Anesthesia in Thoracotomy
This study aims to compare awake thoracic epidural anesthesia and general anesthesia in thoracotomy.
- Conditions
- Awake, Thoracic Epidural Anesthesia, General Anesthesia, Thoracotomy
- Trial name
- NCT06930183
- Testing
- Awake thoracic epidural anesthesia, General anesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Lumbar Radiculopathy, Lumbar Disc Herniation
Prediction of TEI Success in Sciatica
Rationale: Treatment with transforaminal epidural injections is part of usual care in patients suffering from lumbar radiculopathy.
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- POTEISS (NCT04540068)
- Testing
- Transforaminal Epidural Injection
- Where
- Netherlands
- Volunteers
- 388 people
- Sponsor
- Eduard Verheijen
Spinal Cord Injury, SCI
ARC-IM Therapy To Support and Promote Recovery of Ambulatory Functions in People With Subacute and Chronic Spinal Cord Injury
The EIGER study aims to evaluate the safety and preliminary efficacy of ARC-IM Therapy (Epidural Electrical Stimulation) to support and promote recovery of ambulatory functions, such as walking, in people with subacute and…
- Conditions
- Spinal Cord Injury, SCI, SCI - Spinal Cord Injury, Subacute Spinal Cord Injury
- Trial name
- EIGER (NCT07234903)
- Testing
- ARC-IM Therapy
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Total Knee Anthroplasty, Epidural Analgesia
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty
The goal of this clinical trial is to compare two different epidural analgesia delivery methods for pain control after total knee arthroplasty in adults undergoing elective surgery.
- Trial name
- NCT07605208
- Testing
- Programmed intermittent epidural bolus 6 ml, continuous epidural infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Lumbar Radicular Pain, Spinal
Cutaneous Silent Period-Based Comparison of DRG-PRF and TFESI in Lumbar Radicular Pain
This prospective clinical study compares the effects of two interventional treatments, dorsal root ganglion pulsed radiofrequency (DRG-PRF) and transforaminal epidural steroid injection (TFESI), on patients with lumbar radicular…
- Conditions
- Lumbar Radicular Pain, Spinal, Inhibition
- Trial name
- CSP-LRP (NCT07097532)
- Testing
- Radiofrequency, Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- ahmet başarı
Cesarean Section, Anesthesia, Obstetrical
Dural Puncture Epidural With 27G vs 26G Needles Versus Standard Epidural for Elective Cesarean Delivery
The goal of this clinical trial is to learn whether the dural puncture epidural (DPE) technique shortens the onset time of surgical anesthesia compared with the standard epidural technique in healthy women undergoing elective…
- Conditions
- Cesarean Section, Anesthesia, Obstetrical, Anesthesia, Epidural
- Trial name
- NCT07897045
- Testing
- Standard Epidural Anesthesia, Dural Puncture Epidural With 27G Spinal Needle, Dural Puncture Epidural With 26G Spinal Needle
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ankara City Hospital Bilkent
Labor, Obstetric, Epidural Analgesia, Obstetric
Integrated Intrapartum Supportive Care and Pushing Strategies in Women Receiving Low-Dose Epidural Analgesia
This prospective, three-arm, non-randomized quasi-experimental study aims to evaluate integrated intrapartum supportive care combined with different pushing strategies among women at 37-42 weeks of gestation who receive low-dose…
- Conditions
- Labor, Obstetric, Epidural Analgesia, Obstetric, Labor Duration
- Trial name
- NCT07663500
- Testing
- Integrated Care with Immediate Pushing, Integrated Care with Spontaneous Pushing Group, Standard Routine Care
- Where
- Taiwan
- Volunteers
- 159 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Postdiscectomy Epidural Fibrosis, Pain
Efficacy and Safety of Sodium Hyaluronate Gel Combined With Sodium Bicarbonate Versus Sodium Bicarbonate Alone in Prevention of Failed Back Surgery Syndrome
This study investigates the efficacy and safety of Sodium Hyaluronate gel combined with Sodium Bicarbonate compared to Sodium Bicarbonate alone in preventing Failed Back Surgery Syndrome (FBSS) and epidural fibrosis after lumbar…
- Trial name
- NCT06999993
- Testing
- Sodium hyaluronate jell, Sodium Bicarbonate, Saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Misr University for Science and Technology
Epidural Analgesia, Obstetric, Maternal Satisfaction
Impact of Patient Choice for Epidural Potency on Maternal Satisfaction
This clinical trial will compare two different approaches to epidural analgesia during labor to see which approach leads to higher patient satisfaction after delivery.
- Trial name
- NCT07414407
- Testing
- Patient-selected epidural management, Standard epidural management
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University
Maternal Hypotension, Labor Epidural Analgesia
Maternal and Fetal Clinical Significance of Hypotension Following Labor Epidural Analgesia
The goal of this study is to learn how often blood pressure drops after an epidural for labor and how these drops may affect the parent and the baby.
- Conditions
- Maternal Hypotension, Labor Epidural Analgesia, Fetal Heart Rate Abnormalities
- Trial name
- NCT07272018
- Testing
- Epidural Analgesia (Standard Clinical Care)
- Volunteers
- 480 people
- Sponsor
- The Chaim Sheba Medical Center