Clinical trials: Epidural Analgesia
Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain
Postoperative Pain and Analgesic Use After Total Knee Arthroplasty
This prospective observational study evaluates postoperative pain intensity and analgesic consumption in patients undergoing total knee arthroplasty (TKA) under different anesthesia techniques.
- Conditions
- Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain, Analgesic Consumption
- Trial name
- NCT07457814
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Anesthesia
Magnesium for Shivering in Epidural Lidocaine Deliveries
Magnesium has been shown to decrease the shivering experienced from neuraxial anesthesia. This study aims to investigate whether magnesium decreases the shivering experienced in parturients undergoing labor epidural anesthesia…
- Trial name
- Mag-SHIELD (NCT03439358)
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Preoperative Warming, Prewarming
Preoperative Patient Warming for Prevention of Perioperative Hypothermia in Major Abdominal Surgery
The study should evaluate how long patients undergoing major abdominal surgery under combined general/epidural anaesthesia have to be actively warmed preoperatively to prevent perioperative hypothermia and postoperative…
- Conditions
- Preoperative Warming, Prewarming, Perioperative Hypothermia, General Anaesthesia
- Trial name
- THER-6 (NCT01795482)
- Testing
- Forced-air warming
- Where
- 2 sites in Germany
- Volunteers
- 99 people
- Sponsor
- University Hospital Schleswig-Holstein
Hemodynamic Instability
Effect of Remazolam on Hemodynamics During Hepatectomy
There is high incidence of hemodynamic instability in patients undergoing hepatectomy with low central venous pressure, especially in general anesthesia combined with epidural anesthesia.
- Trial name
- NCT06565715
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Jun Zhang
Patients With Acute Pain Admitted to the Intensive Care Unit
Epidural vs. Systemic Analgesia in the Intensive Care Unit
Many patients admitted to the general intensive care unit suffer from pain, whether acute or chronic. Those patients include post-operative patients, multi trauma, acute pancreatitis and patients with multiple rib fractures.
- Trial name
- NCT04996524
- Testing
- epidural analgesia
- Where
- Israel
- Volunteers
- 647 people
- Sponsor
- Meir Medical Center
Maternal Hypotension, Labor Epidural Analgesia
Maternal and Fetal Clinical Significance of Hypotension Following Labor Epidural Analgesia
The goal of this study is to learn how often blood pressure drops after an epidural for labor and how these drops may affect the parent and the baby.
- Conditions
- Maternal Hypotension, Labor Epidural Analgesia, Fetal Heart Rate Abnormalities
- Trial name
- NCT07272018
- Testing
- Epidural Analgesia (Standard Clinical Care)
- Volunteers
- 480 people
- Sponsor
- The Chaim Sheba Medical Center
Postoperative Pain, Satisfaction with Care
Thoracic Spinal Versus Thoracic Epidural Anesthesia for Patients with Chronic Obstructive Pulmonary Disease Undergoing Supine Percutaneous Nephrolithotomy for Management of Renal Stones.
Owing to the elevated risk of perioperative comorbidities, chronic obstructive and restrictive pulmonary disorders can be a challenging task for the anesthetist.
- Trial name
- NCT06663488
- Testing
- Thoracic epidural anesthesia, Thoracic spinal anesthesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Pain
Epidrum for Thoracic Epidural Analgesia
The purpose of this study is to evaluate the use of the Epidrum device to identify the epidural space in patients requiring thoracic epidural analgesia.
- Trial name
- Epidrum-Tho (NCT01597466)
- Testing
- Epidural catheter placement
- Where
- 2 sites in France
- Volunteers
- 46 people
- Sponsor
- Hopital Foch
Anesthesia Complications
Effect of Sufentanil and Ropivacaine
The investigators study the efficacy of epidural sufentanil/ropivacaine for analgesia labor in primiparas so as to decrease perinatal complications of analgesia labor.
- Trial name
- NCT02488291
- Testing
- 0.25 sufentanil, 0.5µg/ml sufentanil, 0.1% ropivacaine
- Volunteers
- 120 people
- Sponsor
- Fudan University
Labor Pain
The Effect of Metrics Based Performance Based Progression in Provision of Labor Epidural Analgesia
Procedural skills are an important determinant of clinical outcomes for certain patient groups. Training for procedural skills in the medical profession is still largely based on an apprenticeship model.
- Trial name
- NCT02185079
- Testing
- Training to proficiency, Conventional training
- Where
- Ireland
- Volunteers
- 16 people
- Sponsor
- Cork University Hospital
Postoperative Pain
Role of Opioids in Epidural Solutions
It is unclear whether addition of opioids to epidural solutions for postoperative analgesia is beneficial. In this multicenter randomized double-blinded trial, we aim to test the primary hypothesis that epidural solutions…
- Trial name
- NCT04251962
- Testing
- Bupivacaine, Fentanyl
- Where
- Israel
- Volunteers
- 135 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Gall Stone Disease, Polyp
Combined Spinal Epidural Anesthesia and General Anesthesia for Laparoscopic Cholecystectomy
The aim of this study was to compare general anesthesia (GA) and combined (epidural and spinal) anesthesia (CA) for laparoscopic cholecystectomy. General anesthesia is a gold standard for laparoscopic cholecystectomy(LC).
- Trial name
- NCT02317510
- Testing
- combined anesthesia, general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Epidural Anesthesia, General Anesthesia
Thoracic Epidural Versus General Anesthesia for Laparoscopic Cholecystectomy
Eighty two patients planned to undergo elective laparoscopic cholecystectomy were divided into two groups, T and G, randomly. In Group T all patients underwent laparoscopic cholecystectomy under thoracic epidural anesthesia with…
- Trial name
- NCT04721054
- Testing
- Thoracic epidural effect on heart rate in Laparoscopic Cholecystectomy (bupivacaine and lignocaine), general anesthesia effect on heart rate in Laparoscopic Cholecystectomy
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Armed Forces Hospital, Pakistan
Labor Pain
Development and Validation of Metrics Lumbar Labor Epidural Catheter Placement
Procedural skills play an important role in anaesthetic expertise. More focused training and assessment of procedural skills will be needed in the future as training moves from an apprenticeship based training system to…
- Trial name
- NCT02179879
- Testing
- Video validation
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- Cork University Hospital
Lumbar Radiculopathy, Lumbar Disc Herniation
Treatment Response to TFESI and DRG Pulsed RF in Lumbar Spinal Stenosis and Disc Herniation
Lumbar radiculopathy caused by conditions such as lumbar disc herniation (LDH) and lumbar spinal stenosis (LSS) can lead to chronic pain and reduced quality of life.
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Lumbar Spinal Stenosis (LSS)
- Trial name
- NCT07509580
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University
Colorectal Cancer, Pain
Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer Surgery
Colorectal cancer is one of the most common cancers in the industrialized world (12% of all cancers). In Sweden, 6000 new cases of colorectal cancer are reported each year, and almost half of these cases result in death.
- Conditions
- Colorectal Cancer, Pain, Other Complications
- Trial name
- EPICOL (NCT01318161)
- Testing
- Ropivacaine + opioid epidurally, Morphine
- Where
- 2 sites in Sweden
- Volunteers
- 221 people
- Sponsor
- Örebro University, Sweden
Analgesia Disorder, Anesthetic Complication Epidural
Effectiveness of Epidural Anesthesia for Thoracic and Abdominal Surgery
This study aims to evaluate the effectiveness of the epidural analgesia in patients having elective thoracic and abdominal surgery under general anesthesia combined with epidural analgesia in Siriraj Hospital.
- Conditions
- Analgesia Disorder, Anesthetic Complication Epidural, Adverse Reaction to Epidural Anesthesia
- Trial name
- NCT02315261
- Testing
- Elective Thoracic and Abdominal Surgery Patients
- Where
- Thailand
- Volunteers
- 364 people
- Sponsor
- Siriraj Hospital
Gastrostomy
Transversus Abdominis Plane Block on Stress Response
This study evaluates the effect of transversus abdominis plane(TAP) block combined with general anesthesia on perioperative stress response in patients undergoing radical gastrectomy.
- Trial name
- NCT03035916
- Testing
- Transversus abdominis plane block, Epidural anesthesia, control
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Jilin University