Clinical trials: Epidural Placement
Verification of Needle Tip Placement in the Lumbar Epidural Space
CompuFlo® Assessment Study for the Epidural Space Verification
The purpose of this pivotal study is to demonstrate safety and effectiveness of the CompuFlo® Epidural Computer Controlled System (referred to hereafter as CompuFlo® Epidural) for the epidural space verification.
- Trial name
- COMPASS (NCT02378727)
- Testing
- Active: Comparator Loss Of Resistance Syringe, Experimental: CompuFlo® Epidural System
- Where
- 5 sites in United States
- Volunteers
- 400 people
- Sponsor
- Milestone Scientific, Inc
Analgesia, Epidural
Neuraxial Ultrasound for Thoracic Epidural Placement
This blinded, randomized study compares standard palpation to ultrasound-assisted landmark identification of the thoracic spine for thoracic epidural catheterization.
- Trial name
- NCT02785055
- Testing
- Thoracic Epidural Placement, Bupivacaine 0.05%, Hydromorphone 0.01mg/mL
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Needle Phobia
Lidocaine Patch for Epidural Placement Pain in Laboring Women
Needle phobia can negatively affect the patient experience and may contribute to anxiety during labor procedures. During epidural placement, a standard intradermal lidocaine skin wheal is administered before Tuohy needle…
- Trial name
- NCT07700108
- Testing
- Lidocaine patch 4%, 1% Lidocaine Skin Wheal
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ohio State University
Epidural Placement
Real-time Ultrasound-guided Paramedian Epidural Access: Evaluation of a Novel In-plane Transverse View Technique
The aim of this study is to demonstrate the feasibility of a new technique using real time ultrasound guided paramedian approach to the epidural space.
- Trial name
- NCT01686243
- Testing
- epidural needle placement with echogenic 17G Tuohy needles (Pajunk TuohySono), standard epidural placement
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Cleveland Clinic
Low Ejection Fraction Patients, Fracture Tibia
Unilateral Epidural Block Versus Ultrasound Guided Combined Femoro-sciatic Nerves Block for Patients With Low Ejection Fraction
compare unilateral epidural anesthesia versus femoral/sciatic nerve block by ultrasound guided as anesthetic technique for cases with low ejection fraction undergoing insertion of nail tibia for fixation of fracture shaft tibia.
- Trial name
- NCT05506501
- Testing
- unilateral epidural anesthesia, Ultrasound guided femoro/ sciatic nerve block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Fluoroscopy for Spine Surgery
A Prospective Study of LessRay Enhanced Versus Standard Fluoroscopic Visualization in Surgical Placement of Spinal Cord Stimulator
The purpose of this study is to gather information comparing LessRay Enhanced fluoroscopy with the current standard of fluoroscopy.
- Trial name
- NCT02827539
- Testing
- LessRay, Standard Fluoroscopy
- Where
- United States
- Sponsor
- Duke University
Epidural Placement
Epidural Wave Form Analysis vs Fluoroscopic Guidance for Thoracic Epidural Placement
The primary objective of this study is to compare the effectiveness of epidural waveform analysis (EWA) with fluoroscopic guidance for confirmation of successful epidural placement.
- Trial name
- NCT07217457
- Testing
- Epidural Waveform Analysis
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Obesity, Pregnancy
A Trial of the Use of Ultrasound to Aid the Insertion of Combined Spinal Epidural Anaesthesia
The study will establish whether the use of ultrasound scanning with a purpose built probe will aid the insertion of the needles for epidural and spinal anaesthesia for obese women undergoing elective caesarean section The study…
- Trial name
- NCT00166699
- Testing
- ultrasound
- Where
- 5 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- NHS Greater Glasgow and Clyde
Pain, Epidural Analgesia
"Loss of Resistance" Versus CompuFlo® for Epidural Placement
The purpose of this study is to compare how well the CompuFlo® computerized syringe pump works as compared to the traditional method of inserting an epidural (a needle placed in one's back to give pain medicine).
- Trial name
- NCT00178750
- Testing
- 18G Tuohy epidural needle, CompuFlo® computerized syringe pump
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Analgesia, Epidural
Pulsatile Pressure Waveform to Confirm Correct Placement of the Epidural in Laboring Patients
Epidural analgesia is highly effective for labor pain relief and is widely chosen by pregnant patients. However, placement of the epidural needle can be challenging in pregnant patients due to lax tissue ligaments and edema so…
- Trial name
- NCT02395796
- Testing
- Epidural Pressure Waveform
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Normal Delivery Pain
A Non Invasive Confirmatory Sign for Correct Epidural Catheter Placement During Normal Vaginal Delivery
Epidural anesthesia for pain control during normal vaginal delivery is a blind maneuver and so we need a confirmatory sign for being in the correct epidural space.
- Trial name
- NCT06371456
- Testing
- epidural catheter placement
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Dislocation, Infection
Fixation of Thoracic Epidurals Influencing Catheter-related Infections and Dislocation
Major interest in our investigation is to find out whether distinct fixation techniques influence catheter dislocation and/ or incidence of local inflammation.
- Conditions
- Dislocation, Infection, Line Colonisation, Line Insertion Site
- Trial name
- TDPAFD (NCT01402778)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Labour Analgesia, Epidural Anaesthesia
Higher vs Lower Lumber Epidural Catheter Insertion During Labour: A Randomised Trial to Compare Efficacy.
This study will randomise pregnant women to labour epidural at a higher versus a lower lumbar level. Outcomes relating to success or failure of the epidural catheter at this level will be assessed.
- Trial name
- NCT06850636
- Testing
- Epidural Analgesia
- Where
- Ireland
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- The Rotunda Hospital
Epidural Anesthesia, Spinal Ultrasound
Utility of Ultrasound in Identification of Midline and Placement of Epidural in Severely Obese Parturients
This study will address the utility of ultrasound in the placement of an epidural catheter in severely obese parturients. Identification of midline can often be difficult using the standard method of palpation in obese patients.
- Conditions
- Epidural Anesthesia, Spinal Ultrasound, Obesity
- Trial name
- NCT03100968
- Testing
- Palpation, Ultrasound
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Post Dural Puncture Headache
Post Dural Puncture Headache After Accidental Dural Puncture
Epidural anesthesia is associated with potential risks and complications, post dural puncture headache (PDPH) one of the most recognized with epidural or spinal anesthesia.
- Trial name
- NCT01448590
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Anesthesia, Pain
Combined Spinal Epidural Urinary Retention
The investigators hypothesize that many parturients can, in fact, spontaneously micturate with low dose combined spinal epidural analgesic doses given for labor and that Foley catheterization is unnecessary in the majority of…
- Conditions
- Anesthesia, Pain, Urinary Retention
- Trial name
- NCT01597791
- Testing
- Foley catheter, No foley catheter
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Northwestern University
Anesthesia, Safety Issues
Sonographic Predictors of Difficult Epidural Placement.
Epidural placement is a commonly used procedure for pain management during labor, delivery, and surgeries. However, epidural placement is often considered a technically challenging and complex procedure that requires a high level…
- Conditions
- Anesthesia, Safety Issues, Epidural; Anesthesia, Headache
- Trial name
- PREC-EPI (NCT05893264)
- Testing
- Data collection
- Where
- Italy
- Sponsor
- University of Padova
Surgery
A Factorial Trial of Ultrasound and Manometry to Improve the Success of Thoracic Epidural Placement
To investigate the use of ultrasound and manometry to increase the success rate of thoracic epidural placement. The use of ultrasound for lumbar epidural catheter placement is well established and is thought to assist in…
- Trial name
- USA-MAN-TE (NCT03559023)
- Testing
- Ultrasound Only, Manometry Only, Ultrasound Plus Manometry
- Where
- United States
- Volunteers
- 480 people
- Sponsor
- Oregon Health and Science University
Pain
Insertion Distance of Thoracic Epidural Catheters in the Context of Thoracotomy Procedures.
This study is designed to compare thoracic epidural catheter insertion distances, in order to determine which is the best for pain relief following a thoracotomy. HYPOTHESIS : 1.
- Trial name
- NCT00754195
- Testing
- Thoracic epidural catheter
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pregnancy
Three-Dimensional Ultrasound (3D US) in Parturients
The purpose of this study is to compare accuracy of a new three-dimensional ultrasound (3D US) technique with the traditional palpation method for identification of the needle insertion site on patients' skin before epidural…
- Trial name
- NCT01523249
- Testing
- Lumbar 3D ultrasound scanning and palpation (Ultrasonix )
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia