Clinical trials: Epiretinal Macular Membrane
Epiretinal Macular Membrane, Cataract Extraction
Epiretinal Macular Membrane and Cataract Extraction
The investigators proposed to assess the functional and anatomical outcomes of cataract and idiopathic epiretinal macular membrane extraction in combined and consecutive surgeries.
- Trial name
- NCT00851760
- Testing
- Consecutive surgery, Combined surgery
- Where
- France
- Volunteers
- 174 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Macular Holes, Epiretinal Membrane
Safety and Efficacy Evaluation of Two Different Brilliant Blue G Dyes as Staining Agent in Vitreo Retinal Surgery.
This is a prospective, Open-label, comparative clinical study to asses two brilliant blue G dyes as staining agent in Vitro Retinal Surgery.
- Trial name
- NCT05086588
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Epiretinal Membrane
Role of Nepafenac in Reducing Macular Volume After Epiretinal Membrane Surgery
The purpose of this study is to compare the macular volume of patients treated with a 3-month course of topical Nepafenac (0.1% solution) to patients treated with a placebo course following epiretinal membrane surgery.
- Trial name
- NCT00818844
- Testing
- Nepafenac 0.1%, BSS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Idiopathic Epiretinal Membrane
Macular Resurfacing Using Autologous ILM Patch Transposition for Idiopathic Epiretinal Membrane
Idiopathic epiretinal membrane is a condition in which abnormal tissue grows on the surface of the retina and can cause blurred vision and distortion.
- Trial name
- NCT07767539
- Testing
- Non-Inverted Autologous Internal Limiting Membrane (ILM) Patch Transposition, Conventional Epiretinal Membrane and Internal Limiting Membrane Peeling
- Volunteers
- 90 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Epiretinal Membrane, Macular Hole
Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal
The purpose of this trial is to compare the ability of two doses of OT-551 ophthalmic solution and drug-free solution to safely and effectively prevent or delay the progression of nuclear cataracts that frequently develop as a…
- Trial name
- NCT00333060
- Testing
- OT-551 ophthalmic solution
- Where
- 16 sites in United States
- Volunteers
- 164 people
- Sponsor
- Othera Pharmaceuticals
Macular Edema, Radiation Retinopathy
Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole
This phase I trial will assess primarily the safety and secondarily anti-inflammatory effect of Episcleral Dexamethasone in patients suffering from macular edema and other disorders of the retina, choroid and vitreous.
- Conditions
- Macular Edema, Radiation Retinopathy, Branch Retinal Vein Occlusion, Epiretinal Membrane
- Trial name
- NCT04120311
- Testing
- Episcleral Dexamethasone
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Targeted Therapy Technologies, LLC
Macular Pucker, Macular Hole
Membrane Blue Versus Infracyanine Green
To compare possible toxicities of membrane blue and infracyanine green in vivo by macular function and peripheral visual field.
- Trial name
- NCT00555269
- Volunteers
- 30 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Pseudoexfoliation Syndrome
Vitreous Proteomics of Patients Suffering From Pseudoexfoliation Syndrome
Determination of proteins and their levels in the vitreous of eyes with or without pseudoexfoliation syndrome (PEX)
- Trial name
- NCT07506551
- Testing
- Liquid chromatography mass spectrometry
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Macular Holes, Macular Pucker
Efficacy and Safety Evaluation of MONOBLUE DUAL View and MONOBLUE ILM View Vital Stains
In this study, the investigators aim to collect data regarding the efficiency and safety of two dyes used intraoperatively in vitrectomy to stain intraocular tissues.
- Conditions
- Macular Holes, Macular Pucker, Vitreomacular Traction
- Trial name
- NewBlueDyes (NCT05517473)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Glaucoma, Macular Pucker
Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) Study
Since the introduction of vitrectomy in 1971, this procedure has become the third most frequently performed ophthalmic surgery. Approximately 225,000 vitrectomies are performed annually in the United States and indications…
- Conditions
- Glaucoma, Macular Pucker, Macula Hole, Vitreomacular Traction
- Trial name
- PROVE (NCT01162356)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Macular Disease, Rhegmatogenous Retinal Detachment
Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery
Based on the progress of cataract surgery, intraocular lens development, vitreoretinal surgery and anesthesia technology in recent years, the purpose of this study is to develop a new type of more accurate and minimally invasive…
- Conditions
- Macular Disease, Rhegmatogenous Retinal Detachment, Epiretinal Membrane, Cataract
- Trial name
- NCT05588037
- Testing
- FLACS +PPV+IOL + air, FLACS +PPV+IOL + epiretinal membrane peeling + Ozurdex, FLACS + PPV+IOL + internal limiting membrane peeling + air
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Macular Edema
Prophylactic Ketorolac Post Epiretinal Membrane Surgery
Evaluate the efficacy of ketorolac 0.5%, a topical non-steroidal anti-inflammatory drug (NSAID), to prevent macular edema after epiretinal membrane surgery.
- Trial name
- NCT00974753
- Testing
- Ketorolac 0.5%, Saline drops
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Queen's University
Ophthalmologic Complication, Epiretinal Membrane
Measuring Subjective Quality of Vision and Metamorphopsia Before and After Epiretinal Membrane and Macular Hole Surgery
Assessing metamorphopsia and quality of vision pre and post epiretinal and macular hole surgery
- Conditions
- Ophthalmologic Complication, Epiretinal Membrane, Metamorphopsia, Macular Holes
- Trial name
- MQUEST (NCT05171621)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Hayley Westwood
Vitrectomy, Retinal Detachment
Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter
Report efficiency and clinical outcomes using 25-gauge, bevel-tip, 20000 cut per minute vitrectomy probe among eyes with various vitreo-retinal diseases
- Conditions
- Vitrectomy, Retinal Detachment, Vitreous Hemorrhage, Macular Holes
- Trial name
- HYPE (NCT04404296)
- Testing
- 25-gauge, bevel-tip, 20000 cut per minute pars plana vitrectomy
- Where
- Philippines
- Volunteers
- 50 people
- Sponsor
- Peregrine Eye and Laser Institute
Retinal Detachment, Epiretinal Membrane
PIONEER: Intraoperative and Perioperative OCT Study
OCT provides high-resolution information regarding the anatomic structure of the tissues of the eye in a 2-dimensional and 3-dimensional view. Much of this information is not able to be recognized by a clinician.
- Conditions
- Retinal Detachment, Epiretinal Membrane, Macular Hole, Fuchs Endothelial Dystrophy
- Trial name
- PIONEER (NCT02423161)
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Epiretinal Membranes, Macular Holes
Blue-Blocking IOLs in Combined Surgery
Although commonly used in cataract surgery, the use of the blue light-filter IOLs in vitrectomy combined with cataract surgery has not been reported yet.
- Conditions
- Epiretinal Membranes, Macular Holes, Cataract
- Trial name
- NCT00537992
- Testing
- combined surgery
- Volunteers
- 60 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Vitreomacular Adhesion
Intravitreal Gas for Vitreomacular Adhesion
Vitreomacular adhesion causes symptoms of blurry vision, distortion, and double vision. It is due to an abnormal separation of the vitreous gel from the surface of the retina and macula.
- Trial name
- RELEASE (NCT02001701)
- Testing
- Intravitreal Injection of sulfahexafluoride gas
- Where
- United States
- Sponsor
- Northern California Retina Vitreous Associates
Macular Hole, Epiretinal Membrane
Optical Coherence Tomography - Rescan During Dissection of Macular Membranes
In our study , the investigators will use the microscope with OCT ( Lumera with RESCAN OCT ) coupled to assess the extent , depth and change of retinal architecture in the perioperative period .
- Conditions
- Macular Hole, Epiretinal Membrane, Traction Syndrome Vitreomacular, Proliferative Vitreoretinopathy
- Trial name
- NCT02748421
- Testing
- Lumera Microscope with OCT RESCAN, Conventional Microscope
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Macular Pucker
Compare ELP in Patients With Elective Phaco-VTX Surgery in One Eye and a Single Lens Phaco Surgery on the Other Eye
The aim of the study is to gain more insight into the potential impact of a vitrectomy (removal of the vitreous) on postoperative effective position of the intraocular lens (IOL).
- Trial name
- ELP (NCT04397068)
- Testing
- phaco-vitrectomy
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven