Clinical trials: Epiretinal Membranes
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Epiretinal Membrane
Outcomes of Vitrectomy Combined With Subtenon Triamcinolone Injection for the Idiopathic Epiretinal Membrane
This study compares the anatomical and visual outcomes of patients with idiopathic epiretinal membrane(ERM) treated by vitrectomy and membrane peeling with or without subtenon triamcinolone acetonide injection
- Trial name
- NCT01630876
- Testing
- Vitrectomy only group, Combined therapy group
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yeungnam University College of Medicine
Epiretinal Membrane
Prevalence and Risk Factors of Epiretinal Membrane in Diabetic and Non-diabetic Patients
Numerous terms have been used to describe epiretinal membrane (ERM): macular pucker, epimacular membrane, surface-wrinkling retinopathy, cellophane maculopathy and preretinal macular fibrosis.
- Trial name
- NCT03362580
- Testing
- Slit lamp examination, Undilated 7-field color fundus photography, Color scan
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Laurence Postelmans
Epiretinal Membrane of Both Eyes
Optical Coherence Tomography Angiography (OCTA) Changes in Patients With Epiretinal Membranes (ERM) With and Without Peeling of the Internal Limiting Membrane (ILM)
Main objective The objective is to compare two surgical options in vitrectomies for epiretinal membranes using parameters of optical coherence tomography angiography.
- Trial name
- NCT05287009
- Testing
- ILM nonpeeling, ILM peeling
- Where
- Austria
- Volunteers
- 51 people
- Sponsor
- Medical University of Graz
Idiopathic Epimacular Membrane
Prospective, Single-blind Study Assessing the Benefit/Risk Ratio of Internal Limiting Membrane (ILM) Peeling During Epimacular Membrane (EMM) Surgery (Peeling)
The epimacular membrane (EMM) is a degenerative condition associated with age, with a variable impact on vision. Treatment is surgery based and consists of a vitrectomy followed by a peeling of the epimacular membrane using a…
- Trial name
- Peeling (NCT02146144)
- Testing
- ILM Peeling
- Where
- 6 sites in France
- Volunteers
- 213 people
- Sponsor
- Nantes University Hospital
Idiopathic Epiretinal Membranes
Diagnostic Reliability of OCT Biomarkers for iERM
Several optical coherence tomography (OCT) biomarkers with potential to influence postsurgical outcomes after vitrectomy with membrane peeling for idiopathic epiretinal membranes (iERM) have been described in single predictor…
- Trial name
- NCT04997876
- Testing
- Biomarker analysis
- Where
- Austria
- Volunteers
- 136 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract, Vitreous Hemorrhage
Surgical Procedure Efficiency Evaluation stuDy
The purpose of this real-world evidence study is to compare surgical procedure times for UNITY® VCS and CONSTELLATION® Vision System.
- Conditions
- Cataract, Vitreous Hemorrhage, Retinal Detachment, Macular Pucker
- Trial name
- NCT07228091
- Testing
- UNITY VCS, CONSTELLATION
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Alcon Research
Epiretinal Membrane
Quantification of Metamorphopsia in Patients With Epiretinal Membranes
Aim of this study is to examine metamorphopsia before and 3 months after vitrectomy with membrane peeling among patients with idiopathic epiretinal membranes.
- Trial name
- NCT05138315
- Testing
- Metamorphopsia quantification
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Macular Holes, Macular Pucker
Efficacy and Safety Evaluation of MONOBLUE DUAL View and MONOBLUE ILM View Vital Stains
In this study, the investigators aim to collect data regarding the efficiency and safety of two dyes used intraoperatively in vitrectomy to stain intraocular tissues.
- Conditions
- Macular Holes, Macular Pucker, Vitreomacular Traction
- Trial name
- NewBlueDyes (NCT05517473)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Epiretinal Macular Membrane, Cataract Extraction
Epiretinal Macular Membrane and Cataract Extraction
The investigators proposed to assess the functional and anatomical outcomes of cataract and idiopathic epiretinal macular membrane extraction in combined and consecutive surgeries.
- Trial name
- NCT00851760
- Testing
- Consecutive surgery, Combined surgery
- Where
- France
- Volunteers
- 174 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Macular Holes, Intraocular Lens Opacification
Oral Sedation in Vitreoretinal Surgery
The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.
- Conditions
- Macular Holes, Intraocular Lens Opacification, Vitrectomy, Vitreous Hemorrhage
- Trial name
- NCT04346095
- Testing
- Oral Sedatives with or Without Analgesia, Intravenous Sedatives with or Without Analgesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Epiretinal Membrane
Comparision of Retinal Function and Macular Structure After 27G Pars Plana Vitrectomy With Minimal Illuminiation
Purpose: To analyze the clinical benefits of using the NGENUITY 3D Visualization System in vitreoretinal surgery with low levels of endo-illumination, focusing on functional and structural retinal protection in patients with…
- Trial name
- ERM (NCT06798285)
- Testing
- Pars Plana Vitrectomy Standard, Pars Plana Vitrectomy 3D
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Pomeranian Medical University Szczecin
Eye Diseases
Next Generation Ophthalmic Irrigating Solution Posterior Segment Study
The purpose of this study is to evaluate the safety of Next Generation Ophthalmic Irrigating Solution (NGOIS) compared to BSS PLUS for use during surgery for removal of epimacular membrane and vitrectomy.
- Trial name
- NCT00333203
- Testing
- Next Generation Ophthalmic Irrigating Solution (NGOIS), BSS Plus
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Alcon Research
Macular Hole, Macular Pucker
Comparison of Postoperative Aqueous Flare After 20G Versus 23G Pars Plana Vitrectomy
To compare postoperative inflammation and breakdown of blood-retinal barrier as measured by a laser flare-cell meter in 20G versus 23G vitrectomy.
- Trial name
- 20Gvs23G (NCT01969929)
- Testing
- 20G Vitrectomy, 23G vitrectomy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Cologne
Macular Pucker, Macular Hole
Membrane Blue Versus Infracyanine Green
To compare possible toxicities of membrane blue and infracyanine green in vivo by macular function and peripheral visual field.
- Trial name
- NCT00555269
- Volunteers
- 30 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Epiretinal Membrane
Epiretinal Membrane in Patients With DR.
To report the prevalence of ERM among patients with diabetic retinopathy, and the possible associated risk factors.
- Trial name
- NCT07241845
- Testing
- OCT
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Assiut University
Epiretinal Membrane Surgery
Post-surgical Functional Results in Patients With Epiretinal Membrane Undergoing Controlled Macular Detachment
This study aims to evaluate postsurgical functional changes in patients with advanced epiretinal membrane (ERM) (stages 3 and 4) by integrating a controlled macular detachment with a balanced salt solution to the conventional ERM…
- Trial name
- DMER25 (NCT07095907)
- Testing
- Pars plana vitrectomy with epiretinal membrane peeling and controlled macular detachment
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Retinal Detachment, Full Thickness Macular Hole
Inflammasomes in Cell Death in FTMH, ERM, and RRD
Prospective study evaluating the role of inflammasomes in cell death in retinal detachment, full thickness macular hole, and epiretinal membrane.
- Conditions
- Retinal Detachment, Full Thickness Macular Hole, Epiretinal Membrane
- Trial name
- NCT03332758
- Testing
- Pars plana vitrectomy, External drainage
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Allen C. Ho, MD
Macular Pucker, Macular Hole
Brilliant Blue Versus Indocyanine Green
A study of non-inferiority design comparing brilliant blue and indocyanine green as intraoperative dye in macular pucker and macular hole.
- Conditions
- Macular Pucker, Macular Hole, Vitreoretinal Surgery
- Trial name
- NCT01083004
- Testing
- Indocyanine green, Brilliant blue arm
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Cologne
Epiretinal Membrane
Retinal Layers and Visual Rehabilitation After Epiretinal Membrane Removal
The purpose of this study is to evaluate the changes in visual acuity, metamorphopsia, and thickness of retinal layers after epiretinal membrane removal and to investigate factors associated with visual function.
- Trial name
- NCT01474655
- Testing
- Pars plana vitrectomy and removal of epiretinal membrane
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center