Clinical trials: Erectile Dysfunction
Hypoactive Sexual Desire Disorder, Erectile Dysfunction
A Combined Psycho-pharmacological and Brain Imaging Study of Human Sexuality
The current study combines a molecular genetic perspective, self report and brain imaging to the study of human sexuality in control subjects and individuals from a sexual disorder clinic.
- Trial name
- NCT00569413
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Metabolic Syndrome, Coronary Heart Disease
Hämeenlinna Metabolic Syndrome Research Program: Surrogate Indicators for Atherosclerosis
Mechanisms that link metabolic syndrome to atherosclerosis are incompletely understood. As a part of Hämeenlinna Metabolic Syndrome Research Program (HMS) surrogate indicators for atherosclerosis are studied in 120 men with…
- Trial name
- HMS-02 (NCT01119404)
- Where
- 4 sites in Finland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kanta-Häme Central Hospital
Erectile Dysfunction
Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of Avanafil
The purpose of this study is to confirm the efficacy and the safety of Avanafil 100mg, 200mg or placebo administered orally for 12 weeks in patients with erectile dysfunction.
- Trial name
- ALERT (NCT00903981)
- Testing
- Avanafil
- Where
- South Korea
- Volunteers
- 208 people
- Sponsor
- JW Pharmaceutical
Hypogonadism, Erectile Dysfunction
Efficacy and Safety Evaluating Fispemifene in the Treatment of Hypogonadal Men With Erectile Dysfunction Unresponsive to PDE5 Inhibitors
The objective of the study is to assess and compare the preliminary efficacy, safety and tolerability of fispemifene 300 mg and placebo given once daily for 8 weeks in the treatment of hypogonadal men with erectile dysfunction…
- Trial name
- NCT00415571
- Testing
- Fispemifene (once daily for 8 weeks)
- Where
- 14 sites in United States
- Volunteers
- 72 people
- Sponsor
- QuatRx Pharmaceuticals Company
Erectile Dysfunction
The Pharmacological Basis for the Increase in Visual Time Constants Induced by Single Oral Doses of Sildenafil
Sildenafil and similar drugs have been used for several years to treat erectile dysfunction. It has been noticed that in some people, sildenafil causes a subtle increase in the length of time that visual images that we see are…
- Trial name
- NCT00463957
- Testing
- sildenafil, tadalafil
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Erectile Dysfunction
To Evaluate The Effect Of Ketoconazole, Ritonavir and Erythromycin on the Safety and Pharmacokinetics of Avanafil
This study is being conducted to examine the effect of three CYP3A4 inhibitors (ketoconazole, erythromycin and ritonavir) on the single dose pharmacokinetics of avanafil.
- Trial name
- NCT00770042
- Testing
- Ritonavir, Ketoconazole, Erythomycin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Erectile Dysfunction
Energy Specific Far Infrared Radiation Treatment for Erectile Dysfunction
A preliminary study to determine the possibility of using far infrared (FIR) radiation to treat impotency.
- Trial name
- NCT00573209
- Testing
- Far Infrared Radiation
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- GAAD Medical Research Institute Inc.
Erectile Dysfunction
Evaluating the Efficacy of Vardenafil in Subjects With Erectile Dysfunction (ED) Administered 12, 18 or 24 Hours Prior to Intercourse
Erectile dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient for satisfactory sexual performance.
- Trial name
- NCT00667979
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Volunteers
- 264 people
- Sponsor
- Bayer
Erectile Dysfunction
Evaluating of the Efficacy and Safety of Vardenafil in Subjects With Erectile Dysfunction
Erectile dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient for satisfactory sexual performance.
- Trial name
- NCT00662441
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Volunteers
- 102 people
- Sponsor
- Bayer
Impotence
Tadalafil Taken Daily Compared to Placebo on Improvement of Getting and Maintaining an Erection and Sexual Quality of Life
To determine if tadalafil 5 mg daily compared to placebo when given for 12 weeks improves getting and maintaining an erection in men with erectile dysfunction and if there are improvements in the sexual quality of life of the man…
- Trial name
- NCT00422734
- Testing
- tadalafil
- Where
- 19 sites in United States, Austria and 3 more
- Volunteers
- 342 people
- Sponsor
- Eli Lilly and Company
Erectile Dysfunction (ED)
Efficacy Study of RX-10100 to Treat Erectile Dysfunction (ED)
The primary objective of this Phase IIa trial is to determine the effective doses and treatment period for an upcoming RX-10100 Phase IIb trial in subjects with erectile dysfunction (ED).
- Trial name
- NCT00693056
- Testing
- RX-10100 5mg, RX-10100 10mg, RX-10100 15mg
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Rexahn Pharmaceuticals, Inc.
Impotence, Erectile Dysfunction
The Management of Erectile Dysfunction With Placebo Only
Placebo-controlled randomized clinical trials (RCT) are the gold standard to provide applicable evidence for clinical practice. A vast number of RCTs for treatment of several disorders has shown a mean placebo effect of 30%.
- Trial name
- DAFA06 (NCT00882934)
- Testing
- Induction to efficient treatment, Doubt to the efficacy of treatment, Induction to ineffective treatment
- Volunteers
- 123 people
- Sponsor
- Rio de Janeiro State University
Erectile Dysfunction
Study to Investigate Effect of a New Drug (PF-00446687) in Males Suffering From Erectile Dysfunction
The purpose of this study is to investigate the effect of up to 200 mg of PF-00446687 on erectile activity in males suffering from erectile dysfunction as well as examining the safety and toleration of the drug.
- Trial name
- NCT00862888
- Testing
- PF-00446687, Sildenafil
- Where
- 3 sites in Norway, United Kingdom
- Volunteers
- 39 people
- Sponsor
- Pfizer
Cardiovascular High-Risk, Chronic Heart Failure
Association of Multiple CardiOvascular Risk Factors and Erectile Function Across Europe
The purpose of the study is to evaluate the influence of cardiovascular risk factors, heart failure and cardiovascular drug therapy on erectile function in cardiovascular high-risk patients.
- Trial name
- AMORE-Eur (NCT00468637)
- Where
- 4 sites in Germany, Italy and 1 more
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Saarland
Impotence
Improvement of Erectile Dysfunction by Fluvastatin in Patients With Cardiovascular Risk Factors
The purpose of the study is to determine the effect of fluvastatin on penile arterial blood flow and erectile function in patients with arteriogenic ED and cardiovascular risk factors.
- Trial name
- NCT00382161
- Testing
- Fluvastatin-sodium
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital, Saarland
Hypertension, Ventricular Remodeling
Efficacy and Safety of Valsartan Plus Hydrochlorothiazide in Patients With Slight Hypertension and Target Organ Damage
Patients with slight increase in blood pressure levels have an increased cardiovascular risk. In particular this has been demonstrated also in subjects with high-normal blood pressure in whom an exaggerated blood pressure…
- Conditions
- Hypertension, Ventricular Remodeling, Erectile Dysfunctions
- Trial name
- NCT00687206
- Testing
- Valsartan 160mg plus HCT 25mg
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Erectile Dysfunction
Efficacy and Safety Study of Combined Oral and Injection Therapy for Erectile Dysfunction
Erectile dysfunction (ED or impotence) is a common medical condition affecting many men world wide. The most commonly used treatment for ED are oral medications like Viagra (sildenafil), Levitra (vardenafil) and Cialis…
- Trial name
- NCT00507286
- Testing
- combination of various doses of sildenefil and alprostadil
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Keogh Institute for Medical Research
Prostatic Hyperplasia, Urinary Bladder, Overactive
A Randomized, Double-Blinded, Placebo-Controlled, Two-Way Crossover Study to Investigate the Safety and Toleration of Single Dose Sildenafil in Subjects Receiving Chronic UK-369,0031
To investigate the safety and overall tolerability of co-administration two PDE5 inhibitors UK369,003 and sildenafil
- Conditions
- Prostatic Hyperplasia, Urinary Bladder, Overactive, Erectile Dysfunction
- Trial name
- NCT00814736
- Testing
- UK369,003, sildenafil
- Where
- Singapore
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Pfizer
Impotence, Prostate Cancer
Evaluate the Effects of GPI 1485 on Erectile Function Following Bilateral Nerve-Sparing Prostatectomy
In this phase II study, an investigative (not approved by the FDA) drug called GPI 1485 is being assessed to see if it can help preserve erectile function after prostatectomy.
- Trial name
- NCT00090376
- Testing
- GPI 1485
- Where
- 25 sites in United States
- Volunteers
- 240 people
- Sponsor
- Eisai Inc.
Erectile Dysfunction
L-Arginine and Erectile Dysfunction
The purpose of the study is to determine whether the treatment with L-arginine leads to an improvement of erectile dysfunction in patients with erectile dysfunction.
- Trial name
- NCT00777075
- Testing
- L-arginine
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Hannover Medical School