Clinical trials: Erectile Dysfunction (ED)
Erectile Dysfunction, Impotence
PROPPER Prospective Registry of Outcomes With Penile Prosthesis
The purpose of this observational registry is to collect and better understand "real-world" outcomes for men undergoing penile implant surgery to treat erectile dysfunction.
- Trial name
- PROPPER (NCT01383018)
- Testing
- AMS Penile Prosthesis Devices
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,457 people
- Sponsor
- Boston Scientific Corporation
Erectile Dysfunction
A Study in Erectile Dysfunction
The purpose of this trial is to evaluate if treatment with tadalafil once daily will allow men to return to normal erectile function in those who did not have normal erectile function following as-needed (PRN) Phosphodiesterase…
- Trial name
- NCT01130532
- Testing
- Tadalafil
- Where
- 40 sites in United States, Canada
- Volunteers
- 623 people
- Sponsor
- Eli Lilly and Company
Diabetes, Erectile Dysfunction
The Prevalence of Erectile Dysfunction (ED) and ED Related Quality of Life of Diabetic Men
Adult diabetic patients aged above 20 attending the diabetic clinic of National Taiwan University Hospital are invited to attend a face to face screening and interview.
- Trial name
- NCT00173134
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Regenerative Injection of Stem Cells or Stem Cell-derived Exosomes for Erectile Dysfunction (RISE)
The goal of this prospective observational study is to evaluate whether injections of stem cells derived from the patient's own fat tissue (adipose tissue) can improve erectile function in men aged 30 to 75 who have erectile…
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- RISE (NCT06605508)
- Testing
- Autologous Adipose Tissue-Derived Stem Cell Injection for Erectile Dysfunction, Stem cell-derived Exosomes Injection for Erectile Dysfunction
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Jumeirah American Clinic
Erectile Dysfunction
Safety and Efficacy of Autologous Platelet-Rich Plasma for Erectile Dysfunction.
The purpose of this study is to evaluate changes in vascular parameters and International Index of Erectile Function (IIEF) scores with the administration of Platelet Rich Plasma (PRP) to participants with Erectile Dysfunction…
- Trial name
- NCT04396795
- Testing
- Autologous Platelet Rich Plasma, Saline solution
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Miami
Impotence, Depression
Efficacy Study Measuring The Impact Of Treatment With Viagra On The Depressive Symptoms Of Men With Erectile Dysfunction
This study will measure the impact of treatment with Viagra on the depressive symptoms and quality of life in men with erectile dysfunction who have untreated depressive symptoms meeting the DSM-IV criteria for dysthymia or…
- Trial name
- NCT00159809
- Testing
- Viagra (Sildenafil citrate)
- Volunteers
- 140 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Impotence
A Study Of The Safety and Efficacy Of Viagra In Men With Erectile Dysfunction Who Do Not Self Identify.
To compare the efficacy and safety of Viagra (sildenafil citrate) vs. placebo for the treatment of men with ED and at least 1 prespecified risk factor who do not self identify as having ED.
- Trial name
- NCT00343200
- Testing
- Viagra (sildenafil citrate)
- Where
- 48 sites in United States
- Volunteers
- 371 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Low Intensity ShockWave Therapy for ED in Non Responders to PDE5i - a Double Blind Placebo Controlled Study
Low intensity shock waves (LISW) have been proven in animal studies to induce local growth of new blood vessels. The investigators hypothesized that LISW therapy could improve the symptoms of patients with erectile dysfunction…
- Trial name
- LI-ESWT (NCT01262157)
- Testing
- Extracorporeal Shockwave Therapy Generator (Vascuspec), Low intensity shock wave therapy
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rambam Health Care Campus
Erectile Dysfunction, Peripheral Arterial Disease
Predicting Peripheral Arterial Disease in Men With Erectile Dysfunction
Erectile dysfunction is a common complaint and is found frequently in men with hyperlipidemia, hypertension, diabetes and those who smoke. ED may also be an early warning of peripheral arterial disease.
- Trial name
- PREPARED (NCT00743613)
- Testing
- Sexual Health Inventory for Men (SHIM), Ankle-Brachial Index (ABI)
- Where
- 5 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Bruton Avenue Family Practice
Erectile Dysfunction
Research Evaluating an Investigational Medication for Erectile Dysfunction - General ED
This study is being conducted to compare the safety and efficacy of 3 doses of avanafil to placebo in men with mild to severe erectile dysfunction.
- Trial name
- REVIVE (NCT00790751)
- Testing
- avanafil
- Where
- 41 sites in United States
- Volunteers
- 646 people
- Sponsor
- VIVUS LLC
Erectile Dysfunction
Clinical Trial of Topically-applied Glyceryl Trinitrate (GTN) for the Treatment of Erectile Dysfunction (ED)
This study is designed to evaluate the efficacy and safety of MED2005, a topically applied glyceryl trinitrate (GTN) gel administered to the penis of male subjects self-diagnosed with erectile dysfunction (ED) immediately before…
- Trial name
- NCT02495467
- Testing
- Glyceryl trinitrate
- Where
- United Kingdom
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Futura Medical Developments Ltd.
Androgen Deficiency, AD
Hormones and Sexual Function Predict Outcomes in Revascularized Men With Diabetes
The purpose of this study is to find out if androgen deficiency (low levels of testosterone, a male hormone produced by the sex glands) and erectile dysfunction (sexual dysfunction) will predict over time the development of a…
- Conditions
- Androgen Deficiency, AD, Erectile Dysfunction, ED
- Trial name
- HEART-MEND (NCT01190904)
- Where
- 5 sites in United States
- Volunteers
- 568 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Erectile Dysfunction
LI-ESWT Versus Sham Therapy in Men With ED
Hong Kong has an aging population. By the year of 2036, more than 30% of our population will be older than 65 years old1. Aging in male has been shown to correlate with the risk of erectile dysfunction(ED).
- Trial name
- NCT04721834
- Testing
- Low-intensity Extracorporeal Shockwave Therapy
- Volunteers
- 84 people
- Sponsor
- Hospital Authority, Hong Kong
Erectile Dysfunction, Hyperbaric Oxygen Therapy
HBOT Application in Erectile Dysfunction
Recent studies have shown that hyperbaric oxygen therapy (HBOT) can induce angiogenesis and improve impaired organ function. HBOT was also recently suggested as a possible therapy for ED due to surgical injuries.
- Trial name
- HBOTED (NCT02619383)
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 37 people
- Sponsor
- Assaf-Harofeh Medical Center
Erectile Dysfunction (ED)
Sano V First In Human Study to Treat ED
A Prospective, First in Human Study to Evaluate the Safety and Performance of a Flow Modification System
- Trial name
- FMS (NCT03651024)
- Testing
- ED surgery
- Volunteers
- 10 people
- Sponsor
- Sano V Pte Ltd
Erectile Dysfunction (ED)
The Feasibility of Using Dornier Machine in Patients With Erectile Dysfunction, a Pilot Study.
Extracorporeal Shockwave Therapy (ESWT) is a well-established modality for treating various urological and musculoskeletal conditions.
- Trial name
- DED-Pilot (NCT07331961)
- Testing
- extracorporeal shock wave therpy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Erectile Dysfunction
The Effect of Low Intensity Shock Wave Therapy for ED in PDE5i Non Responders
Low Intensity Shock Wave Therapy (LI-ESWT) was shown to have a beneficial effect on ED patients responding to PDE5i's. This study aimed to determine the capability of swt to convert PDE5 inhibitor non responders to sexually…
- Trial name
- LI-ESWT (NCT01272297)
- Testing
- LI-ESWT
- Volunteers
- 29 people
- Sponsor
- Rambam Health Care Campus
Erectile Dysfunction, Hypogonadism, Male
EndoPAT Device for Endothelial Dysfunction in ED
To assess endothelial dysfunction in young men (aged 30-50) with vasculogenic ED identified through penile Doppler ultrasound. To evaluate changes in endothelial function using EndoPAT before and 3-6 months after daily low-dose…
- Conditions
- Erectile Dysfunction, Hypogonadism, Male, Endothelial Dysfunction
- Trial name
- NCT06720597
- Testing
- Daily low-dose PDE5 inhibitor therapy, Testosterone therapy as per clinical guidelines.
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Irvine
Erectile Dysfunction
Pelvic Angiography in Non-Responders to Phosphodiesterase-5 Inhibitors (PANPI)
The specific aim of this pilot study is to describe the angiographic prevalence and pattern of internal pudendal artery (and associated inflow vessel) atherosclerosis in patients with erectile dysfunction who are non-responsive…
- Trial name
- PANPI (NCT00574184)
- Volunteers
- 10 people
- Sponsor
- University of California, Davis
Erectile Dysfunction Following Radical Prostatectomy
Early Shockwave Therapy for Post-RP ED
This pilot study aims to explore the feasibility, safety and effectiveness of two different extracorporeal shock wave therapy (ESWT) protocols for patients receiving nerve-sparing radical prostatectomy (RP).
- Trial name
- NCT03905057
- Testing
- Dornier Aries 2 (with active applicator)
- Where
- Spain
- Volunteers
- 94 people
- Sponsor
- Dornier MedTech Systems