Clinical trials: Erectile Dysfunctions, open to volunteers
Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer
Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy
Prostate cancer is the most common cancer in Australian men. Robot-assisted radical prostatectomy (RARP) - surgical removal of the prostate - is a standard treatment, but it frequently causes erectile dysfunction (ED) and urinary…
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer, Urinary Incontinence Following Surgical Procedure
- Trial name
- ROBOPREP (NCT07576335)
- Testing
- Tadalafil 5 mg, Pelvic Floor Muscle Training (PFMT), Aerobic Exercise Program
- Where
- 3 sites in Australia
- Volunteers
- 64 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Peyronie Disease, Erectile Dysfunction
Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease
The purpose of this research is to determine whether or not low-intensity shockwave therapy (LiSWT) with Xiaflex treatment will result in greater improvements to the curvature of the penis.
- Trial name
- NCT06065436
- Testing
- Collagenase Clostridium Histolyticum, Storz Duolith LiSWT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Erectile Dysfunction Due to Venous Disorder, Erectile Dysfunction (ED)
Embolosclerotherapy Versus Deep Dorsal Vein Revascularization in Venogenic Erectile Dysfunction
Venous leakage is one of the causes of erectile dysfunction and can be managed using different treatment modalities, including surgical ligation and percutaneous embolization.
- Trial name
- venogenic ED (NCT07604194)
- Testing
- Endovascular embolosclerotherapy, Revacularization of deep dorsal vein
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Hospital
Erectile Dysfunction
IT Matters: The Erectile Restoration Registry
The objective of the It MATTERS registry is to collect Real-World Data (RWD) to monitor the safe and effective use of commercially available Boston Scientific Corporation (BSC) penile prostheses
- Trial name
- NCT04200937
- Testing
- Tactra Malleable, Spectra™ Concealable Penile Prothesis, AMS Ambicor™ Inflatable Penile Prosthesis
- Where
- 25 sites in United States, China and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Erectile Dysfunction, Urinary Incontinence
Male Pelvic Floor Muscle Rehabilitation Exercises
Phase I G128 Study Objective The ischiocavernosus (IC) and bulbospongiosus (BS) muscles are vital components of the superficial perineal layer, serving as the foundation for male sexual health and performance.
- Conditions
- Erectile Dysfunction, Urinary Incontinence, Premature Ejaculation
- Trial name
- NCT07451808
- Testing
- Male Pelvic Floor Rehabilitation #1
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dream Video LLC
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy: a Randomized Controlled Trial
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Erectile Dysfunctions
The Purpose of This Study is to Evaluate the Efficacy and Safety of W2505.
The purpose of this study is to evaluate the efficacy and safety of W2505.
- Trial name
- NCT07859202
- Testing
- W2505, W2505-P1, W2505-R
- Where
- South Korea
- Volunteers
- 228 people
- Sponsor
- GL Pharm Tech Corporation
Coronary Artery Disease, Erectile Dysfunction
Pudendal Atherosclerosis by IVUS-NIRS in Men With Coronary Artery Disease
This prospective, single-center, exploratory study will evaluate the association between atherosclerotic and lipid plaque burden in the internal pudendal arteries, assessed by intravascular ultrasound and near-infrared…
- Conditions
- Coronary Artery Disease, Erectile Dysfunction, Atherosclerosis
- Trial name
- PUDENDAL-NIRS (NCT07856199)
- Testing
- Selective Pudendal Angiography, Pudendal IVUS-NIRS Imaging
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Central Militar
Erectile Dysfunction
Shockwave Therapy on Treating Erectile Dysfunction Following Nerve-sparing Radical Prostatectomy.
This study will investigate whether low-intensity extracorporeal shockwave therapy (LiESWT) can help men recover erectile function after nerve-sparing prostate cancer surgery.
- Trial name
- REVIVE (NCT07819084)
- Testing
- Low-Intensity Extracorporeal Shockwave Therapy, Standard of Care
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Manitoba
Hypogonadism, Male, Secondary Hypogonadism
AIM-TEST: Microbiome-Targeted Nutrition for Functional Secondary Hypogonadism
AIM-TEST is a randomized, double-blind, placebo-controlled clinical trial evaluating whether an AI-guided, microbiome-targeted nutritional intervention can increase the body's own testosterone production in men aged 30-65 years…
- Trial name
- AIM-TEST (NCT07761546)
- Testing
- Fixed-Formula Microbiome-Targeted Oral Nutritional Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Varol TUNALI
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
Tractography-Guided Nerve-Sparing in Prostate Cancer
Radical prostatectomy (RP) is an effective treatment leading to a high rate of oncological control. However, despite advances in robot-assisted RP, the genito-urinary function, especially erectile function and urinary continence…
- Conditions
- Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy, Urinary Incontinence Following Surgical Procedure
- Trial name
- PRO-TRACT (NCT07847385)
- Testing
- Prostate Tractography for Nerve-Sparing
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Massimo Valerio
Erectile Dysfunction (ED)
IPP Placement & Intracavernosal Block
The inflatable penile prosthesis (IPP) is the gold standard for surgical management of erectile dysfunction (ED) and there is no consensus on the best postoperative pain management regimen.
- Trial name
- IPP (NCT07246642)
- Testing
- Exparel/bupivacaine mixture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences
Atherosclerotic Cardiovascular Disease (ASCVD), Erectile Dysfunction
Phase IIa Clinical Trial of YN001 in Patients With Atherosclerotic Cardiovascular and Cerebrovascular Diseases and Erectile Dysfunction
This is a randomized, double-blind, placebo-controlled phase IIa clinical trial to evaluate the efficacy and safety of YN001 in patients with atherosclerotic cardiovascular and cerebrovascular diseases and erectile dysfunction
- Trial name
- NCT07311330
- Testing
- YN001 20mg Dose + 5% glucose injection, 5% glucose injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Inno Medicine Co., Ltd.
Hypertension, Erectile Dysfunction
EECP for Erectile Dysfunction in Elderly Hypertensive Patients
Hypertension and erectile dysfunction are common health problems in older men and may share vascular dysfunction as an underlying mechanism.
- Trial name
- NCT07831551
- Testing
- Enhanced External Counterpulsation
- Where
- 2 sites in China
- Volunteers
- 106 people
- Sponsor
- Qilu Hospital of Shandong University
Erectile Dysfunction
Linear Piezoelectric Low Intensity Shockwave Treatment (LI-SWT) for the Treatment of Erectile Dysfunction in PDE5i Non Responder
The goal of this clinical trial is to assess the efficacy and safety of linear piezoelectric Li-SWT for erectile dysfunction patients who have poor treatment respond from PDE5i oral treatment.
- Trial name
- NCT07820748
- Testing
- low-intensity shockwave therapy
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Erectile Dysfunction and Coronary Artery Disease
Assessment of Erectile Dysfunction and Coronary Artery Disease Severity
This study provides a comprehensive bidirectional assessment to determine the prevalence, clinical severity, and anatomical correlation between erectile dysfunction and coronary artery disease severity in patients presenting to…
- Trial name
- BA-EDCAD (NCT07813195)
- Testing
- Selective Coronary Angiography
- Volunteers
- 120 people
- Sponsor
- Assiut University
Erectile Dysfunction
Penile Lengthening Pre-Penile Prosthesis Implantation
The goal of this study is to determine whether or not the use of a penile traction therapy device known as RestoreX prior to implantation of a penile prosthesis can increase the length of the implant used during surgery.
- Trial name
- NCT07053826
- Testing
- Penile Traction Device, Inflatable Penile Prosthesis Implantation
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- J. Peter Rubin, MD
Prostate Cancer, Urinary Incontinence
Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment
This study is being done at Duke Health and includes adult men who have been treated for localized prostate cancer. The goal is to see if it is feasible and acceptable to offer sex therapy by telehealth after prostate cancer…
- Conditions
- Prostate Cancer, Urinary Incontinence, Erectile Dysfunction
- Trial name
- RESTORE-PC (NCT07685249)
- Testing
- Sex Therapy, Pelvic Floor Physical Therapy, Vacuum Erection Device (VED)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Erectile Dysfunction, Tadalafil
Daily Tadalafil as Adjunctive Therapy Versus Monotherapy for PDE5 Inhibitor-Resistant Erectile Dysfunction
This randomized trial will compare daily tadalafil 5 mg as adjunct therapy versus monotherapy in men with on-demand PDE5 inhibitor-resistant erectile dysfunction.
- Trial name
- NCT07753720
- Testing
- Tadalafil; Current on-demand PDE5 inhibitor, Tadalafil 5 mg
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Al-Azhar University
Erectile Dysfunction Following Radical Prostatectomy
Efficacy of RestoreX Penile Traction Therapy In Preserving Erectile Function Post-Prostatectomy
Evaluate the efficacy of the RestoreX penile traction device in preserving erectile function in men undergoing robotic-assisted prostatectomy.
- Trial name
- NCT05244486
- Testing
- RestoreX 1-6 months (randomized phase), RestoreX 6-9 months (open label phase)
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease