Clinical trials: Error, Refractive
Presbyopia
Performance of Two Daily Disposable Multifocal Contact Lenses
This study will compare the performance of two daily disposable multifocal soft contact lenses.
- Trial name
- NCT07444658
- Testing
- Lens A (kalfilcon A), Lens B (stenfilcon A)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia
A Phase 3 Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia
This clinical study will evaluate pilocarpine hydrogen chloride (HCl) ophthalmic solution (AGN-190584) in an expanded participant population to establish efficacy, safety, and tolerability versus the vehicle-control when…
- Trial name
- GEMINI 2 (NCT03857542)
- Testing
- Pilocarpine HCl Ophthalmic Solution, Vehicle
- Where
- 35 sites in United States
- Volunteers
- 427 people
- Sponsor
- Allergan
Refractive Errors, Astigmatism
EyeQue VisionCheck 510(k) Clinical Trial
Demonstrate that refraction measurements from the device agree with refraction measurements from a phoropter within clinically meaningful limits.
- Trial name
- NCT06044688
- Testing
- EyeQue VisionCheck, Phoropter
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Refractive Errors
Comparison of Visual Acuity Performed in Office Versus In Residence
GoCheck has developed and deployed a home-based visual acuity test that may be used in-office or in residence. The test methodology utilizes modified ATS and ETDRS protocols with Sloan optotypes, crowding bars and sophisticated…
- Trial name
- VA IR vs IO (NCT05250986)
- Testing
- GoCheck Kids (iOS), GoCheck Kids (Windows), GoCheck at Home (iOS)
- Where
- 4 sites in United States, Israel
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Gobiquity Mobile Health
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Essilor® Stellest® Lenses Multicentre European Study (SLOMES)
The goal of this post-market clinical follow up Study is to demonstrate the efficacy, safety, acceptability, and quality of life implications of Essilor® Stellest® spectacle lenses in slowing myopia progression in European…
- Trial name
- SLOMES (NCT06263946)
- Testing
- Essilor® Stellest® spectacle lenses
- Where
- 3 sites in France, Ireland and 1 more
- Volunteers
- 150 people
- Sponsor
- Essilor International
Refractive Error
Lubricity Post-Wear - Competitive Lenses Pilot
The purpose of this study is to measure the coefficient of friction of three silicone hydrogel, daily disposable contact lenses after 16 hours of wear.
- Trial name
- NCT02402127
- Testing
- Narafilcon A contact lenses, Stenfilcon A contact lenses, Somofilcon A contact lenses
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Refractive Error
Evaluation of Deposits on Contact Lenses Worn Daily Wear
The purpose of this study was to measure front surface deposits on contact lenses when worn for ten hours.
- Trial name
- NCT00725153
- Testing
- Balafilcon A contact lenses (PureVision), Etafilcon A contact lenses (Acuvue2)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Presbyopia
An Evaluation of the Safety of CSF-1 in Presbyopic Subjects
This is a multi-center, double-masked, vehicle-controlled study. The purpose of the study is to evaluate the safety of CSF-1 compared with vehicle in presbyopic subjects. Subjects will be treated for at least 6 weeks.
- Trial name
- NCT05393895
- Testing
- CSF-1, Vehicle
- Where
- 12 sites in United States
- Volunteers
- 178 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Myopia, Hyperopia
Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers
The purpose of this study was to compare the clinical performance of two different reusable lenses in habitual spherical soft lens wearers.
- Trial name
- NCT06098339
- Testing
- Lens A (fanfilcon A), Lens B (lotrafilcon B)
- Where
- 3 sites in United States, Canada
- Volunteers
- 53 people
- Sponsor
- CooperVision, Inc.
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Roflufocon D
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT02553681
- Testing
- roflufocon D contact lenses, RGP contact lenses made from roflufocon D
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Presbyopia, Pseudophakia
A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near and Intermediate Vision in Pseudophakic Presbyopic Subjects
The objective of this study is to evaluate the safety and effectiveness of the Raindrop Near Vision Inlay implanted in bilateral pseudophakes with presbyopia for improvement of near and intermediate vision.
- Trial name
- NCT02668523
- Testing
- Raindrop Near Vision Inlay
- Where
- 13 sites in United States
- Volunteers
- 400 people
- Sponsor
- ReVision Optics, Inc.
Myopia, Astigmatism
Multicenter Dispensing Study of Biofinity Toric Made-To-Order Lenses in Extended Power Ranges
The study hypothesis is that the Biofinity Toric XR lenses will perform as well as or better than the participants' habitual contact lenses.
- Trial name
- NCT02193178
- Testing
- comfilcon A Toric
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- CooperVision, Inc.
Myopia
Wearability of and Myopia Progression With ZEISS MyoCare Spectacle Lenses
This is a clinical trial evaluating the wearability and effectiveness of three types of ZEISS spectacle lenses in controlling myopia progression.
- Trial name
- NCT07021560
- Testing
- ZEISS MyoCare spectacle lenses, ZEISS SV RX SPH 1.5, ZEISS Clearview
- Where
- Vietnam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ZEISS Vision Care
Hyperopia
Pilot Dispensing Evaluation of a Plus Power Lens
The purpose of this study is to compare the performance of the ACUVUE® ADVANCE® Plus lenses against ACUVUE® ADVANCE® lenses in the plus power parameters.
- Trial name
- NCT01228591
- Testing
- Acuvue Advance Plus, Acuvue Advance
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Evaluation of Functional Superiority of the Morrow eProgressive
Presbyopia is a common age-related condition where the eye loses its ability to focus on nearby objects, typically from around age 45.
- Trial name
- EPACT (NCT07878416)
- Testing
- 3 weeks wearing of study device instead of their current wearing solution
- Where
- 3 sites in Belgium, Italy
- Volunteers
- 50 people
- Sponsor
- Morrow Eyewear
Myopia
Performance Comparison Between Comfilcon A and Senofilcon C Lenses
The aim of this study is to determine the clinical performance of comfilcon A in comparison to senofilcon C.
- Trial name
- NCT02920957
- Testing
- comfilcon A, senofilcon C
- Where
- 5 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Errors
Air Optix Daily Wear Contact Lenses
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term performance and safety of Air Optix Aqua, Air Optix plus HydraGlyde Sphere, and Air Optix plus HydraGlyde Toric soft contact lenses in a…
- Trial name
- NCT05827224
- Testing
- Lotrafilcon B spherical soft contact lenses, Lotrafilcon B spherical soft contact lenses with comfort additive, Lotrafilcon B toric soft contact lenses with comfort additive
- Where
- 5 sites in United States
- Volunteers
- 312 people
- Sponsor
- Alcon Research
Myopia
Performance Evaluation of Different Daily Disposable Silicone Hydrogel Contact Lenses
The goal of this study is to compare the performance of two daily disposable silicone hydrogel contact lenses.
- Trial name
- NCT05805059
- Testing
- Control Contact Lens (stenfilcon A), Test Contact Lens (senofilcon A)
- Where
- 4 sites in United States, Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study
The purpose of this study is to continuously assess the visual performance and safety of DAILIES TOTAL1 soft contact lenses in a real world setting and broader patient base through routine clinical practices.
- Conditions
- Myopia, Hyperopia, Presbyopia, Astigmatism
- Trial name
- NCT06483113
- Testing
- Delefilcon A spherical soft contact lenses, Delefilcon A toric soft contact lenses, Delefilcon A multifocal soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 192 people
- Sponsor
- Alcon Research