Clinical trials: Error, Refractive
Presbyopia
A Study of the Concurrent Use of AGN-190584 and AGN-199201 in Participants With Presbyopia
This study will identify the optimum concentrations of AGN-199201 and AGN-190584 when dosed in combination once a day for the improvement of uncorrected near visual acuity in participants with presbyopia (inability to focus on…
- Trial name
- NCT02595528
- Testing
- AGN-199201 ophthalmic solution, AGN-190584 ophthalmic solution, AGN-190584 vehicle
- Where
- 20 sites in United States
- Volunteers
- 163 people
- Sponsor
- Allergan
Cataract, Presbyopia
Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas
The objective of this study is to evaluate the clinical outcomes of the IC-8 IOL implanted in patients with complex corneas after crystalline lens removal.
- Conditions
- Cataract, Presbyopia, Irregular Astigmatism
- Trial name
- NCT05574270
- Testing
- IC-8 Intraocular Lens (IOL)
- Where
- 2 sites in Philippines, Singapore
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Ametropia
Dispensing Study for the Phenacite Project
Dispensing Study for the Phenacite Project. The investigational test lens was not the final optical design and the study was not used for design validation.
- Trial name
- NCT02436005
- Testing
- Phenacite, comfilcon A
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- CooperVision, Inc.
Myopia
Comparative Study of Two Marketed 1-day Soft Contact Lenses
This study is designed to evaluate ocufilcon D lens compared to ocufilcon B lens in a 1-week crossover, daily wear regimen.
- Trial name
- NCT01464255
- Testing
- ocufilcon D, ocufilcon B
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- CooperVision, Inc.
Refractive Error, Dry Eye
Determination of Cell Population in Solution-Induced Corneal Staining (SICS) and Symptomatic Versus Asymptomatic Lens Wearers
The purpose of the study is to investigate the corneal epithelial cell response associated with lens wear that results in solution-induced corneal staining (Phase1) and to determine the cell appearance in symptomatic and…
- Trial name
- ABBOTSFORD (NCT01629706)
- Testing
- Balafilcon A contact lens, Habitual contact lenses, Renu multi-purpose solution
- Volunteers
- 92 people
- Sponsor
- CIBA VISION
Refractive Errors
Clinical Investigation of a Femtosecond Laser for Corneal Flap Creation
The purpose of this study is to see how safe the WaveLight Ultraviolet Femtosecond Laser, Model 1026 (UV fs-Laser), is for creating corneal flaps during laser-assisted in situ keratomileusis (LASIK) surgery.
- Trial name
- NCT07036835
- Testing
- LASIK Surgery, UV fs-Laser, IR fs-Laser
- Where
- Australia
- Volunteers
- 128 people
- Sponsor
- Alcon Research
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Myopia
A Lifestyle Investigation With Spectacles and Daily Disposable Contact Lenses in Young Patients
The purpose of this study was to evaluate the relative benefits of daily disposable contact lenses versus spectacles in young adults.
- Trial name
- NCT01445652
- Testing
- nelfilcon A contact lens, Spectacles
- Where
- United Kingdom
- Volunteers
- 113 people
- Sponsor
- CIBA VISION
Presbyopia
Long Term Follow-up of the VisAbility™ Micro Insert System for Presbyopic Patients
The objective of this study is to obtain an additional 36 months of safety and effectiveness data from all subjects who were implanted with the VisAbility™ Micro Insert in the VIS-2014 clinical trial.
- Trial name
- NCT03811249
- Testing
- VisAbility™ Micro Insert
- Where
- 13 sites in United States
- Volunteers
- 287 people
- Sponsor
- VisDura, Inc.
Presbyopia
Evaluation of Refractive Outcomes in Patients Undergoing PRESBYOND Using the MEL90 Excimer Laser
The goal of this clinical trial is to collect information on vision outcomes in people aged 45 to 65 who have difficulty seeing clearly at near distances due to aging (a condition called presbyopia).
- Trial name
- NCT06960785
- Testing
- MEL90 excimer laser - PRESBYOND
- Where
- 3 sites in Australia, New Zealand
- Volunteers
- 75 people
- Sponsor
- Carl Zeiss Meditec AG
Presbyopia
A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia
This is a safety, efficacy and pharmacokinetics study of the fixed combination of AGN-199201 and AGN-190584 in participants with presbyopia (inability to focus on items close-up).
- Trial name
- NCT02780115
- Testing
- AGN-199201 ophthalmic solution, AGN-190584 ophthalmic solution, AGN-199201 Vehicle
- Where
- 25 sites in United States
- Volunteers
- 151 people
- Sponsor
- Allergan
Myopia
Clinical Evaluation of Two Daily Disposable Lenses in Neophytes
The purpose of this study is to evaluate the performance of two daily disposable contact lenses in a population of neophytes (new wearers).
- Trial name
- NCT00987623
- Testing
- nelfilcon A contact lens, narafilcon A contact lens
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- CIBA VISION
Myopia
A Study to Evaluate the Safety and Efficacy of DSFNC1 Soft Hydrophilic Contact Lenses and SiHy Color Soft Hydrophilic Contact Lenses
This project is an open, parallel, randomly controlled, and non-inferiority clinical trial of DSFNC1 soft hydrophilic contact lenses with SiHy color soft hydrophilic contact lenses.
- Trial name
- NCT06616480
- Testing
- BenQ Materials DSFNC1 soft hydrophilic contact lenses, Visco SiHy Color soft hydrophilic contact lenses
- Where
- China
- Volunteers
- 192 people
- Sponsor
- BenQ Materials Corporation
Astigmatism
A Clinical Performance of Two Soft Toric Contact Lenses
The study objective was to gather short-term clinical performance data for two soft toric contact lenses.
- Trial name
- NCT05633082
- Testing
- Lens 1 (omafilcon B), Lens 2 (fanfilcon A)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Safety & Efficacy of the Laser Scleral Microporation Procedure
A new minimally invasive procedure for treating presbyopia is being evaluated to determine if there is improvement in near and intermediate vision after treatment
- Trial name
- NCT05068479
- Testing
- Bilateral Laser Scleral Microporation procedure
- Where
- Panama
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- ACE Vision Group, Inc.
Myopia
Assessment of Lotrafilcon A Contact Lenses
The purpose of this 3-month study is to evaluate subjective responses to an upgraded contact lens.
- Trial name
- NCT01185834
- Testing
- Lotrafilcon A upgrade soft contact lens
- Volunteers
- 118 people
- Sponsor
- CIBA VISION
Myopia
Stellest Lenses and Low-concentration Atropine Myopia Control Among Children
The prevalence of myopia is increasing globally, especially in Asian countries. 70-80% of the young population suffers from myopia, and almost 20% have high myopia.
- Trial name
- NCT06344429
- Testing
- Stellest Lenses, Stellest Lenses+0.05% atropine, Single vision Lenses+0.05% atropine
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor-Polylite Taiwan Co., Ltd.
Myopia, Amblyopia
Real Word Study on Myopia Control With Repeated Red Light Therapy for Ages of 3~6 Years Old
Repeated Red Light Therapy had been used as an amblyopia therapy for children as well as the myopia control in primary schools. However, ultra low lever of red light therapy with irradiance of 0.37mW and 0.60mW effectiveness and…
- Trial name
- RMC (NCT05811598)
- Testing
- repeated ultra low lever red light
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Astigmatism
The Clinical Study of Silicone Hydrogel Daily Disposable Stenfilcon A Toric Lens
The aim of this study is to evaluate the clinical performance of stenfilcon A toric lenses compared with etafilcon A toric lenses for astigmatism.
- Trial name
- NCT02801006
- Testing
- stenfilcon A, etafilcon A
- Where
- 2 sites in Japan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Astigmatism
Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses
This is a prospective, multi-center, subject-masked, bilateral, daily wear, two-month dispensing study
- Trial name
- NCT02921412
- Testing
- fanfilcon A
- Where
- 4 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.