Clinical trials: Error, Refractive
Cataract, Presbyopia
Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Intraocular Lens (IOL) in a Korean Population
The purpose of this study is to confirm the effectiveness of the investigational lens in a Korean population, especially for visual performance, quality of vision, and subject satisfaction with the visual outcome, as well as the…
- Trial name
- NCT03268746
- Testing
- AcrySof IQ PanOptix Multifocal IOL
- Where
- 4 sites in South Korea
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Refractive Error Correction
Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process
This study is a multi-site, group sequential, adaptive, randomized, double-masked, 2×2 crossover design, 1-week dispensing study.
- Trial name
- NCT03605303
- Testing
- Test/Control, Control/Test
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract, Astigmatism
AcrySof IQ Toric A-Code Post-Market Clinical Study
The purpose of this study is to clinically confirm the rotational stability of a modified AcrySof IQ toric intraocular lens (IOL) in a Japanese population.
- Trial name
- NCT03350503
- Testing
- AcrySof IQ Toric A-code IOL, Cataract surgery
- Where
- 4 sites in Japan
- Volunteers
- 125 people
- Sponsor
- Alcon Research
Presbyopia
Post-Approval Study With the KAMRA Inlay
KAMRA inlay, to be unilaterally implanted into the cornea of a subject's non-dominant eye. The inlay is to be inserted into a stromal pocket created with a surgical femtosecond laser.
- Trial name
- NCT03173664
- Testing
- KAMRA Inlay
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Presbyopia
Visual Outcomes After Presbyopic Lens Exchange
Evaluation of mean preoperative and postoperative Corrected distance visual acuity (CDVA) after Refractive Lens Exchange in presbyopic patients
- Trial name
- RELAX (NCT03790592)
- Testing
- trifocal IOL
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Carl Zeiss Meditec AG
Myopia
Clinical Investigation of Buttermere (LENS 271) Soft Contact Lenses
The purpose of the study is to compare clinical performance between two soft contact lenses.
- Trial name
- NCT06609018
- Testing
- Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
- Where
- United Kingdom
- Volunteers
- 73 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Myopia
Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 1
The primary objective of this study is to evaluate the overall performance of PRECISION1 contact lenses when compared to Biotrue ONEday contact lenses.
- Trial name
- NCT04527978
- Testing
- Verofilcon A contact lenses, Nesofilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Alcon Research
Refractive Errors, Ametropia
Clinical Performance of Two Commercial, Daily Disposable Contact Lenses
The purpose of this study is to compare the clinical performance of DAILIES TOTAL1 ( DT1) contact lenses with Infuse contact lenses.
- Conditions
- Refractive Errors, Ametropia, Myopia
- Trial name
- NCT05010512
- Testing
- Delefilcon A contact lenses, Kalifilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Aphakia, Presbyopia
Evaluation of AcrySof IQ Vivity Extended Vision Intraocular Lenses
The purpose of this post-market study is to describe the long-term safety and performance of AcrySof IQ Vivity and AcrySof IQ Vivity Toric intraocular lens (IOL) models in a real-world setting through routine clinical practice.
- Conditions
- Aphakia, Presbyopia, Residual Refractive Cylinder
- Trial name
- NCT06541795
- Testing
- AcrySof IQ Vivity Extended Vision IOL
- Where
- United States
- Sponsor
- Alcon Research
Cataract, Refractive Error
A Comparative Study of TECNIS Symfony Plus IOL and a Trifocal IOL
This is a multicenter, prospective, randomized, subject- and evaluator-masked, bilateral-implant study conducted at up to 15 sites worldwide.
- Trial name
- NCT04156737
- Testing
- TECNIS Symfony plus IOL Model ZHR00V, Trifocal Intraocular lens
- Where
- 5 sites in New Zealand, Philippines and 1 more
- Volunteers
- 205 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Presbyopia
Multifocal High ADD Contact Lens Proof of Concept Trial
The purpose of this study is to evaluate the visual performance of a new multifocal High ADD contact lens compared to the currently-marketed AIR OPTIX® AQUA MULTIFOCAL (AOAMF) High ADD Contact Lens.
- Trial name
- NCT02117544
- Testing
- Lotrafilcon B multifocal contact lenses (new), Lotrafilcon B multifocal contact lenses
- Volunteers
- 268 people
- Sponsor
- Alcon Research
Cataract, Corneal Astigmatism
Clinical Investigation of the Safety and Effectiveness of an Investigational Model of the TECNIS® Intraocular Lens
This study will be a prospective, multicenter, bilateral, comparative, three-way masked (Sponsor, subject and evaluator), randomized clinical investigation conducted at up to 15 sites.
- Trial name
- BRAVO (NCT03949335)
- Testing
- IOL Model ZFR00V, IOL Model ZCB00
- Where
- 15 sites in United States
- Volunteers
- 272 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia
Tolerability of a Novel Spectacle Design With Reduced Peripheral Contrast
Prospective, randomized, subject-masked 3-arm clinical study to assess the pediatric acceptability across three iterations of a novel spectacle lens design.
- Trial name
- WALNUT (NCT03761758)
- Testing
- Spectacle lenses
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Ametropia
Ocular Responses to Short and Long-term Lens Wear
The purpose of this study was to determine whether ocular surface sensitivity to pneumatic, mechanical and chemical stimulation would be affected by the use of the combination of a specific silicone hydrogel lens material with…
- Trial name
- NCT00722891
- Testing
- Purevision Lenses with ReNu Multiplus, Purevision Lenses with Optifree RepleniSH
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Comparative Study of the Wearing Satisfaction of Two Soft Contact Lens Designs.
To evaluate the wearing satisfaction of a new design of the PureVision soft contact lenses.
- Trial name
- NCT00768885
- Testing
- PureVision 1, PureVision 2
- Where
- Japan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
A Clinical Comparison of Two Soft Toric Contact Lenses
The aim of this study is to compare the short-term clinical performance of two toric contact lenses.
- Trial name
- NCT06758089
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia Correction, Astigmatism
A Planned Study at Multiple Sites is Being Done to Compare the Results of Two Types of Trifocal Toric Intraocular Lenses Used in Cataract Surgery
To evaluate the clinical outcomes and patient satisfaction of two commercially available trifocal toric intraocular lenses Primary Objective: To compare the distance-corrected intermediate visual acuity between the two trifocal…
- Conditions
- Presbyopia Correction, Astigmatism, Cataract
- Trial name
- NCT07232615
- Testing
- Optiflex TRIO Intraocular Lens, AcrySof® IQ PanOptix®
- Where
- 6 sites in Germany, India and 1 more
- Volunteers
- 138 people
- Sponsor
- Biotech Healthcare Holding Gmbh
Presbyopia
A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-190584 in Both Eyes Twice Daily
Currently available treatments for presbyopia (old eye) include nonsurgical options (spectacles or contact lenses) and surgical options, however, each has its own risks and limitations.
- Trial name
- Virgo (NCT04983589)
- Testing
- Pilocarpine HCl, Vehicle
- Where
- 23 sites in United States
- Volunteers
- 230 people
- Sponsor
- Allergan
Refractive Errors
Prospective Study of the Health Benefits of Ultra-Violet Filtering Contact Lenses
The purpose of this study is to examine the short-term protective effect of Ultra-Violet filtering contact lenses on macular pigment ocular density.
- Trial name
- NCT01444313
- Testing
- narafilcon A contact lens, nelfilcon A soft contact lenses
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Aphakia, Astigmatism
Clareon IOL Retrospective Data Collection
The purpose of this study is to provide real world evidence (RWE) on the performance of the Clareon ultraviolet absorbing (UVA) intraocular lenses (IOLs) to support the overall body of evidence on the Clareon IOL family.
- Trial name
- NCT05796674
- Testing
- Clareon UVA IOL, WaveTec Optiwave Refractive Analysis (ORA) System, Cataract surgery
- Where
- United States
- Volunteers
- 1,090 people
- Sponsor
- Alcon Research