Clinical trials: Error, Refractive
Laser in Situ Keratomileusis
Patient-Reported Outcomes With LASIK:PROWL-1
This study evaluates a questionnaire designed to measure satisfaction and ophthalmic-related quality of life (QOL)in up to 550 active duty subjects prior to and six months following state-of-the-art laser in situ keratomileusis…
- Trial name
- PROWL-1 (NCT01526291)
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Food and Drug Administration (FDA)
Laser in Situ Keratomileusis
Patient Reported Outcomes With LASIK: PROWL-2
This study evaluates a questionaire designed to measure satisfaction and ophthalmic-related quality of life (QoL) of 300 civilian participants prior to and three months following state-of-the-art laser in situ keratomileusis…
- Trial name
- PROWL-2 (NCT01655420)
- Testing
- LASIK
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Food and Drug Administration (FDA)
Refractive Errors, Self-Examination
Comparison of a Smartphone Based Self Refraction Tool With Conventional Refraction Error Estimation Methods
Self evaluating tools based on smartphone devices are public available on the market for each person. The tools are used to estimate the existing refractive error for each eye of a patient. Hereafter, e.g.
- Trial name
- NCT03419351
- Testing
- Smartphone, Autorefractor, Individual
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Retinopathy of Prematurity
Refractive Error and Biometry in Retinopathy of Prematurity
The investigators compared long-term refractive and biometric outcomes in children with retinopathy of prematurity who received two different anti-vascular endothelial growth factor agents.
- Trial name
- NCT03334513
- Testing
- Bevacizumab, Ranibizumab
- Volunteers
- 35 people
- Sponsor
- San Ni Chen
Cataract, Refractive Error
A Study of Interventions to Reduce Disability From Visual Loss in Nursing Home Residents
The purpose of this clinical trial is to determine if interventions within the nursing home to restore vision, or cope with visual loss, in residents with visual impairment result in improvement or less decline in mobility…
- Conditions
- Cataract, Refractive Error, Low Vision
- Trial name
- NCT00348621
- Testing
- Visual impairment intervention program
- Where
- United States
- Volunteers
- 2,544 people
- Sponsor
- Johns Hopkins University
Presbyopia, Refractive Error
Dispensing Study to Assess the Visual Performance of Optimised Prototype Contact Lenses
The aim of this study is to assess the visual performance of multiple optimised prototype soft contact lens designs compared to commercially available contact lenses.
- Trial name
- NCT02484586
- Testing
- Etafilcon A, Nelfilcon A, Nesofilcon A
- Where
- Australia
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision
Refractive Errors
Direct Comparison of SVOne Obtained Refraction to Subjective Manifest Refraction
The purpose of the study is to compare the final glasses prescription based on refraction obtained with SVOne device to the final prescription obtained via subjective manifest refraction.
- Trial name
- NCT03222661
- Testing
- Refraction
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Smart Vision Labs
Refractive Errors
Retrospective Study of the Health Benefits of Ultra-Violet Filtering Contact Lenses
The purpose of this study is to examine the long term effect of ultra-violet filtering contact lenses on macular pigment density (MPOD) and accommodative function.
- Trial name
- NCT01444053
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors
Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
Study to evaluate the safety and efficacy of HI-BRITE large diameter rigid gas permeable contact lens (hexafocon b) test when worn on a daily wear basis in the correction of myopia/hyperopia/astigmatism/presbyopia/ and irregular…
- Trial name
- NCT02812316
- Testing
- HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
- Where
- Taiwan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Disorders, Refractive
Comparison of Corneal Stromal Tissue Consumption (LATAC)
In refractive surgery, stromal ablation depth is fundamental because it determines the thickness of the residual posterior wall.
- Trial name
- LATAC (NCT02519673)
- Testing
- Measurement of stromal tissue ablation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Disorders, Refractive
A Comparison of Two Devices for Measuring the Central Thickness of the Cornea Before and After Surgery (CECOT)
Corneal topography allows the measure of the radii of curvature and of the thickness of the cornea. It is essential for diagnosis in ophthalmology and allows to highlight corneal irregularities such as a keratoconus, or too thin…
- Trial name
- CECOT (NCT02522416)
- Testing
- Central corneal thickness measurement
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Ametropia
Endothelial Bleb Response With Toric Lenses
Evaluate the short-term corneal response of oxygen deprivation when using toric contact lenses. The response will be noted by endothelial bleb formation in both open eye and closed eye state.
- Trial name
- NCT00630305
- Testing
- alphafilcon A toric, lotrafilcon B toric, senofilcon A toric
- Where
- Australia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Dry Eye, Ametropia
Osmoprotective Containing Lubricants in Dysfunctional Tear Syndrome and Post Refractive Surgery Patients
The purpose of this project is to determine the effectiveness of an eyewash osmoprotective lubricant comparing to castor oil containing and non-osmoprotective lubricants in different types of DTS and post refractive surgery…
- Trial name
- NCT01741987
- Testing
- Optive ®, Fresh Tears ®
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Myopia, Refractive Error
Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface
The purpose of this study is to utilize in-vivo confocal microscopy to describe differences in corneal epithelial immune status across three lens care regimens in new contact lens wearers.
- Trial name
- NCT01250925
- Testing
- ReNu MultiPlus® MultiPurpose Solution, OPTI-FREE® RepleniSH®, Clear Care®
- Where
- 2 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Refractive Error
WaveLight® Refractive Flap Accuracy Study
The purpose of this study is to evaluate the accuracy of the WaveLight FS200 femtosecond laser, as assessed by 1 day and 1 month post-operative optical coherence tomography (OCT) anterior segment corneal measurements compared to…
- Trial name
- NCT01941485
- Testing
- WaveLight® Refractive Suite, LASIK surgery
- Volunteers
- 60 people
- Sponsor
- Alcon Research
Refractive Error
Comparison of Two Marketed Silicone Hydrogel Lenses
The purpose of this study is to evaluate cholesterol sorption by AIR OPTIX® AQUA lenses compared to ULTRA lenses after 30 days of wear.
- Trial name
- NCT02495948
- Testing
- Lotrafilcon B contact lenses, Samfilcon A contact lenses, Hydrogen peroxide solution
- Volunteers
- 168 people
- Sponsor
- Alcon Research
Refractive Error
Clinical Evaluation of MyDay™ and 1-DAY ACUVUE® TruEye®
The purpose of this study is to evaluate the functional vision of 2 daily disposable silicone hydrogel contact lenses using Time Controlled Visual Acuity (TCVA) measurements at high luminance and high contrast after 10+/-3 days…
- Trial name
- NCT02388763
- Testing
- Stenfilcon A contact lenses, Narafilcon A contact lenses
- Volunteers
- 66 people
- Sponsor
- Alcon Research
Refractive Error
Fitting Children With Contact Lenses
The purpose of this three-month study is to compare the quality of life and ease of fit among children wearing investigational single-vision contact lenses, commercially marketed single-vision contact lenses, and commercially…
- Trial name
- COPPER (NCT01233089)
- Testing
- Lotrafilcon B contact lens, investigational, Lotrafilcon B contact lens, commercial (AIR OPTIX AQUA), Lotrafilcon B multifocal contact lens, commercial (AIR OPTIX AQUA MULTIFOCAL)
- Where
- Canada
- Volunteers
- 194 people
- Sponsor
- CIBA VISION
Refractive Error
Formula Identification (FID) 114657 in Contact Lens Wearers
The purpose of this study is to evaluate the thickness of the pre-lens tear lipid layer after 2 hours of lens wear with use of FID 114657 compared to saline control.
- Trial name
- NCT02293538
- Testing
- FID 114657 eye drops (10 ml), Saline control eye drops (15 ml), Habitual contact lenses
- Volunteers
- 234 people
- Sponsor
- Alcon Research
Refractive Error
Clear Care® Plus vs. PeroxiClear™
The purpose of this study is to evaluate Clear Care® Plus compared to PeroxiClear™ for mean residual peroxide in used lens cases collected at Day 30 after neutralization at recommended storage time.
- Trial name
- NCT02413333
- Testing
- Clear Care Plus contact lens solution, PeroxiClear contact lens solution, Silicone hydrogel contact lenses
- Volunteers
- 133 people
- Sponsor
- Alcon Research