Clinical trials: Error, Refractive
Presbyopia
Post-Approval Study With the KAMRA Inlay
KAMRA inlay, to be unilaterally implanted into the cornea of a subject's non-dominant eye. The inlay is to be inserted into a stromal pocket created with a surgical femtosecond laser.
- Trial name
- NCT03173664
- Testing
- KAMRA Inlay
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.
This study seeks to evaluate the impact of wearing a new daily disposable soft contact lens on the neophyte population.
- Trial name
- NCT00708032
- Testing
- spectacles, narafilcon A soft contact lenses
- Where
- United Kingdom
- Volunteers
- 74 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Astigmatism
Z8 OCT-controlled 2D vs 3D LASIK
The aim of this study was to test the hypothesis that OCT-guided 110 µm targeted flaps will result in accurate, predictable, and precise thickness flaps, with low complication rates when performed and compared using both 2D and…
- Trial name
- NCT04426175
- Testing
- 2D and 3D cutting method using a low energy Femtosecond laser LDV Z8 for LASIK flap cutting
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Zentrumsehstarke Hamburg
Refractive Error
DAILIES TOTAL1® - Comparative Assessment of Tear Film Evaporation
The purpose of this study is to evaluate the tear film evaporation of symptomatic soft contact lens wearers in the absence of contact lens wear and after at least 8 hours of contact lens wear.
- Trial name
- NCT02517567
- Testing
- Delefilcon A contact lenses, Narafilcon A contact lenses, Somofilcon A contact lenses
- Volunteers
- 37 people
- Sponsor
- Alcon Research
Astigmatism, Glaucoma
Influence of Trabeculectomy and Phaco-trabeculectomy on Corneal Astigmatism
This study investigates the effects of trabeculectomy and combined phacoemulsification plus trabeculectomy on corneal astigmatism.
- Trial name
- NCT02945202
- Testing
- Biometry, Refraction, Corneal Topography
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Refractive Errors
Air Optix® Night and Day® Aqua Continuous Wear
The purpose of this retrospective, Post-Market Clinical Follow-Up (PMCF) study is to assess the long term performance and safety of Air Optix® Night and Day® Aqua (AONDA) contact lenses in a real-world setting when worn as 30…
- Trial name
- NCT05992675
- Testing
- Lotrafilcon A contact lenses, Balafilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 1,256 people
- Sponsor
- Alcon Research
Myopia
Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic Center
This randomized controlled trial aims to evaluate the efficacy and safety of low-dose topical atropine sulphate (0.05%), a non-selective muscarinic antagonist, in slowing the progression of myopia and ocular axial elongation in…
- Trial name
- NCT07164092
- Testing
- Atropine 0.05% Eye drops
- Volunteers
- 45 people
- Sponsor
- Mansoura University
Myopia, Astigmatism
LASIK iDesign vs SMILE
The study will compare the 6-month visual outcomes (i.e., visual acuity, contract sensitivity, higher order aberrations), quality of vision (i.e., double vision, glare, starburst, halos, etc.) and dry eye symptoms of patients…
- Trial name
- TG-LASIK vs SM (NCT07126756)
- Testing
- STAR S4 IR Excimer Laser System, VisuMax 400 Surgical Laser
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- 59th Medical Wing
Myopia, Astigmatism
PMCF Study on SMILE Treatment of Myopia With and Without Astigmatism
The primary objective of this PMCF investigation is to systematically collect safety and effectiveness data with the VISUMAX 800 laser in clinical daily routine SMILE use for the purpose of post market surveillance.
- Trial name
- NCT04884672
- Testing
- SMILE
- Where
- 5 sites in Denmark, Germany and 2 more
- Volunteers
- 237 people
- Sponsor
- Carl Zeiss Meditec AG
Myopia, Small-incision Lenticule Extraction (SMILE) Surgery
Potential Risk Factors and Predictive Model Construction of OBL During SMILE
To explore the prediction of OBL by deep learning model in SMILE surgery
- Trial name
- NCT06577012
- Testing
- Small incision lenticule extraction
- Where
- China
- Volunteers
- 4,678 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Myopia
A Study to Evaluate the Performance of Two Designs of Soft Toric Lenses
The objective of the study is to evaluate the product performance of the Bausch + Lomb toric investigational contact lenses compared to the currently marketed PureVision toric contact lenses.
- Trial name
- NCT01309867
- Testing
- Investigational Toric Lens, PureVision Toric Lens
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
A Study to Evaluate the Product Feasibility of a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses developed by Bausch + Lomb.
- Trial name
- NCT01412983
- Testing
- Bausch & Lomb Test lens, Ciba Vision soft contact lens
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Evaluating and Improving Functional Driving Vision of Patients With Astigmatism
Small amounts of astigmatism are often uncorrected in contact lens wearers. The effect with respect to driving is unknown, but it could threaten safe operation of a motor vehicle, especially under conditions such as nighttime…
- Trial name
- NCT02624791
- Testing
- 1-DAY ACUVUE® MOIST contact lenses, 1-DAY ACUVUE® MOIST for ASTIGMATISM contact lenses, No contact lenses
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Induced Defocus to the Retina
Defocus Induced Changes on Choroidal Thickness
The goals of this study are to assess the short-term (10-60 minutes) effects of different magnitudes of myopic and hyperopic optical defocus on the transient thickness of the choroid in children and adults, as well as to assess…
- Trial name
- NCT03954886
- Testing
- Plus powered optical lens
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Houston
Presbyopia
Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients
A multicenter, randomized, double-Blind, crossover, placebo-controlled Phase II clinical Study to evaluate the efficacy and safety of BRIMOCHOL PF and CARBACHOL PF in the treatment of Chinese patients with presbyopia.
- Trial name
- NCT06948357
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.
Hyperopia
Photorefractive Keratectomy (PRK) for Hyperopia After Radial Keratotomy
To assess the efficacy, predictability, stability and safety of corneal wavefront-guided photorefractive keratectomy (PRK) for correcting hyperopia and astigmatism after radial keratotomy (RK).
- Trial name
- NCT00917657
- Testing
- Photorefractive keratectomy
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo
Myopia
Study of Atropine Sulfate Eye Drops(0.01%) in Treating Near-work-induced Transient Myopia in Children
This study is a randomized, double-blind, placebo-controlled, parallel-group study to evaluate the safety and efficacy of atropine sulfate eye drops (0.01%) in treating transient myopia induced by near work tasks (NITM) in…
- Trial name
- NCT06697522
- Testing
- Atropine Sulfate
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Ocumension Therapeutics (Suzhou) Co., Ltd
Distance Viewing, Prolonged Near Viewing
Measuring How Quickly the Eye Focuses After Sustained Viewing of Close-up Images and Videos
In this experiment, subjects will view a cross pattern on the screen and be asked to focus their eyes on it. The cross pattern will look like it is moving towards and away from the eye in a back-and-forth motion.
- Trial name
- NCT07679048
- Testing
- Near viewing first, Distant viewing first
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rochester Institute of Technology
Presbyopia
Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients
The purpose of this study is to evaluate the effect of a multi-focal contact lens on symptomatic patients.
- Trial name
- NCT01016652
- Testing
- etafilcon A multifocal contact lens, etafilcon A Contact Lens
- Where
- 8 sites in United States
- Volunteers
- 49 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Effectiveness and Safety of the TENEO 317 Model 2 Excimer Laser to Treat Myopia With or Without Astigmatism by Transepithelial Photorefractive Keratectomy
A Study to Investigate the Effectiveness and Safety of the TENEO 317 Model 2 Excimer Laser to Treat Myopia with or without Astigmatism by Transepithelial Photorefractive Keratectomy
- Trial name
- NCT06618547
- Testing
- TENEO 317 Model 2 excimer laser
- Volunteers
- 140 people
- Sponsor
- Bausch & Lomb Incorporated
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