Clinical trials: Error, Refractive
Myopia
The Effect of Hinge Position and Hinge Width on Corneal Sensation and Dry Eye After IntraLase LASIK Procedure
Corneal sensation is known to play a role in tear secretion. Decreased sensation leads to decreased tear production; and when bilateral, leads to a decreased blink rate as well. Dry eyes are a common side effect of LASIK.
- Trial name
- IDES (NCT00803478)
- Testing
- LASIK
- Where
- United States
- Sponsor
- University of Michigan
Cataract, Lens Opacities
PMCF Retrospective Study Outcomes of a Monofocal Toric Intraocular Lens
This is a monocentric retrospective, open-label clinical study in patients after unilateral or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC and executed only with standard of care…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- NCT05055076
- Testing
- PODEYE TORIC
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Beaver-Visitec International, Inc.
Presbyopia
Clinical Evaluation of Two Multifocal Contact Lenses
The aim of this study is to evaluate the patient subjective experiences of the monthly multifocal lens when compared to the daily disposable multifocal lens after 15 minutes of daily wear.
- Trial name
- NCT05457608
- Testing
- Lens A, Lens B
- Where
- Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Vistakon Investigational Contact Lenses Worn for Daily Wear
This study compares the performance of an investigational contact lens to a currently marketed lens.
- Trial name
- NCT00717249
- Testing
- galyifilcon A control lens, galyfilcon A with a silver additive
- Where
- 20 sites in United States
- Volunteers
- 529 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Controlling Myopia Progression With Soft Contact Lenses
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression.
- Trial name
- NCT00762970
- Testing
- Test Lens 1, Test Lens 2, Control Lens
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Efficacy of PEG-400 and Systane Artificial Tears (Alcon) on Quality of Vision
To evaluate the effect of PEG-400 and Systane on quality of vision after LASIK.
- Trial name
- NCT00627302
- Testing
- PEG-400, Systane
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Myopia, Astigmatism
Photorefractive Keratectomy (PRK) : Comparison of Corneal Haze Between Two Modes of De-epithelialisation (Laser Versus Manual Alcohol)
surgical correction of ametropia. A number of improvements have been introduced to overcome the side effects and complications such as corneal haze, epithelial irregularities induced by wound healing, pain and delayed visual…
- Trial name
- H-TransPKR (NCT05072977)
- Testing
- TransPRK, Alcohol PRK
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Myopia, Progressive
Crossover RCT of TAMER Lenses in Myopia Control
This study is a prospective, randomized, crossover clinical trial with a planned proposed enrollment of 120 Chinese male and female subjects aged 6-12 years without systemic or ocular diseases to follow up their cycloplegic…
- Trial name
- NCT06329986
- Testing
- TAMER Lens Spectacle, SV lenses
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Refractive Errors, Myopia
Pilot Clinical Performance of a Silicone Hydrogel Lens for Up to Six Nights of Extended Wear
The purpose of this clinical study is to evaluate the on-eye performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn continuously for up to 1 week.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT04403542
- Testing
- Lehfilcon A contact lens, Comfilcon A contact lens
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Myopia
A Study to Evaluate the Safety and Efficacy of Eye Secret UV Aspheric Silicone Soft (Hydrophilic) 1Day Color Contact Lens
This was a prospective, randomized, open label, parallel, active-controlled clinical study to assess the safety and efficacy of Silicone Color Contact Lens for vision correction.
- Trial name
- NCT06527586
- Testing
- soft contact lens
- Where
- 3 sites in Taiwan
- Volunteers
- 131 people
- Sponsor
- Yung Sheng Optical Co., Ltd.
Myopia
Dispensing Overnight Study in Lenses
The purpose of the study is to evaluate the fit and performance of an investigational soft contact lens in comparison with a currently marketed lens.
- Trial name
- NCT00349856
- Testing
- Biofinity
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Astigmatism
Revive Toric RWE Study
This is a post-market observational clinical investigation. The objective of this observational study is to evaluate the visual performance and HCP satisfaction of REVIVE samfilcon B custom toric contact lenses.
- Trial name
- NCT06785194
- Testing
- REVIVE samfilcon B custom toric contact lenses
- Where
- 3 sites in United States
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia, Cataract
Feasibility Study of Laser Treatment of the Crystalline Lens to Correct Presbyopia
The study will evaluate whether the LensAR laser system can be used in the lens of the eye to increase the ability to read and/or see near objects
- Trial name
- NCT01062412
- Testing
- LensAR Laser System
- Where
- Philippines
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- LensAR Incorporated
Under- and Uncorrected Significant Refractive Errors
Effectiveness of Alternative Approaches to Providing Spectacles in Tanzanian Secondary School Students
The aim of this study was to compare the effectiveness of two interventions, namely providing free spectacles or only a prescription to students with insufficiently corrected or uncorrected significant refractive errors.
- Trial name
- NCT00249275
- Testing
- spectacles
- Where
- Tanzania
- Volunteers
- 250 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Myopia
Myopia Control Using Bright Light Therapy, Myopic Defocus and Atropine
The purpose of the study is to investigate the effect of bright light therapy, myopic defocus, atropine and the combination in myopia control in schoolchildren.
- Trial name
- NCT04923841
- Testing
- High intensity light box for bright light therapy and single vision spectacle lenses, High intensity light box for bright light therapy and Defocus Incorporated Multiple Segments (DIMS) spectacle lenses, High intensity light box for bright light therapy and atropine 0.01% eye drop and and single vision spectacle lenses
- Where
- Hong Kong
- Volunteers
- 577 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Presbyopia
Evaluating Two Multifocal Daily Disposable Contact Lenses
The objective of the study was to adapt existing multifocal soft lens wearers to a Control Lens for at least 2 weeks and then evaluate the success of switching them to the Test Lens, with a review after 2 weeks.
- Trial name
- NCT05579886
- Testing
- Control Lens, Test Lens
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Astigmatism
Evaluation of Visual Acuity of the Envista One-piece Acrylic Toric IOL MX60ET
The primary objective of this study is to evaluate rotational stability and functional improvements in visual acuity of the enVista monofocal Toric IOL (MX60ET) following cataract surgery.
- Trial name
- NCT05739656
- Testing
- CATARACT SURGERY
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Errors
Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens
The objective of this clinical investigation is to collect valid scientific safety and effectiveness data on the Acuity 200 (fluoroxyfocon A) Rigid Gas Permeable Contact Lens, manufactured from a newly developed rigid gas…
- Trial name
- Acuity 200 (NCT03971227)
- Testing
- Acuity 200 (Fluoroxyfocon A) contact lens, Acuity 100 (Hexafocon A) contact lens
- Where
- 3 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Acuity Polymers, Inc.
Hyperopia
Safety and Effectiveness of the TENEO 317 Model 2 (1.28 US) Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Hyperopia With or Without Astigmatism
This will be a multicenter, prospective, open label, non-randomized, single arm 12 month study, evaluating the safety and effectiveness of the TECHNOLAS TENEO 317 Model 2 (Software version "1.28 US") excimer laser when used in…
- Trial name
- NCT05264623
- Testing
- TENEO 317 Model 2 excimer laser
- Where
- 9 sites in United States
- Volunteers
- 140 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Juvenile Myopia
Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens
This is a conventional efficacy trial to validate the results from previous clinical trials for younger children; the 12-month efficacy results will be used to predict the 3-year treatment efficacy.
- Conditions
- Myopia, Juvenile Myopia, Myopia Progression
- Trial name
- EUCALYPTUS (NCT06034327)
- Testing
- Single vision, impact-resistant spectacle lenses; Test Arm, Single vision, impact-resistant spectacle lenses; Control Arm
- Where
- 14 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
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