Clinical trials: Error, Refractive
Myopia
Evaluation of Alcon Ladarvision Wavefront-Guided PRK
The purpose of this study is to: 1. determine the safety of wavefront guided PRK 2. evaluate the efficacy of wavefront guided PRK 3. evaluate the differences in visual quality after treatment of wavefront guided PRK
- Trial name
- NCT00412295
- Testing
- Alcon Ladarvision (Wavefront-guided PRK)
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Refractive Errors
Study to Evaluate the Reliability, Validity and Safety of Subjective Mobile Refraction
This study evaluates the reliability, validity and safety of a self administered, subjective refraction test via a mobile medical app (GoEyes) as compared to standard of care subjective manifest refraction performed by a health…
- Trial name
- NCT05049070
- Testing
- Mobile medical application to self administer a subjective refraction test, Standard of care refraction test
- Where
- 12 sites in United States
- Volunteers
- 349 people
- Sponsor
- 1800 Contacts, Inc.
Myopia
Low-Dose Atropine for Treatment of Myopia
Study Objectives The objectives for this randomized trial are: 1. To determine the efficacy of daily low-dose atropine (0.01%) for slowing myopia progression over a two-year treatment period in children aged 5 to less than 13…
- Trial name
- MTS1 (NCT03334253)
- Testing
- Atropine
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- Jaeb Center for Health Research
Myopia
Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILE
This prospective observational cohort study will investigate corneal biomechanical characteristics and their relationships with corneal stromal tissue features in adult patients undergoing clinically indicated small-incision…
- Trial name
- SMILE (NCT07906327)
- Testing
- SMILE
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji University
Myopia
Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software
As new orthokeratology fitting software emerges onto the market, it is of interest to assess their usefulness in guiding eye practitioners with lens fit.
- Trial name
- NCT05389072
- Testing
- control contact lens
- Where
- 4 sites in United States, Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Evaluation of The Clinical Acceptance of Soft Contact Lenses for Myopia Control
The main objective of the study was to evaluate the clinical acceptance of soft contact lenses for Myopia control.
- Trial name
- NCT04709237
- Testing
- omafilcon A control lens, omafilcon A test lens 1, omafilcon A test lens 2
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Ectasia
Intrastromal Corneal Ring for Ectasia After Refractive Surgery (Anel)
To evaluate the clinical outcomes of intrastromal corneal ring segment (ICRS) implantation to correct keratoconus on eyes with prior refractive surgery.
- Trial name
- NCT02008253
- Testing
- INTRASTROMAL CORNEAL RING SEGMENT
- Where
- Brazil
- Volunteers
- 29 people
- Sponsor
- Instituto de Olhos de Goiania
Myopia
Comparative Performance of PureVision, Acuvue Oasys and O2Optix
The objective of this study is to evaluate the performance of the PureVision Contact Lens compared to Acuvue Oasys Contact lens and O2Optix Contact lens when worn on a daily wear basis.
- Trial name
- NCT00640341
- Testing
- PureVision Contact Lens, Acuvue Oasys Contact Lens, O2Optix Contact lens
- Where
- United States
- Volunteers
- 510 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Corneal Astigmatism
Evaluation of the Impact of Corneal Width on Surgically Induced Astigmatism (SIA) and Functional Results After Bimanual 1.4 mm Microincision Cataract Surgery (B-MICS), Coaxial 1.8 mm MICS (C-MICS) and 2.4 mm Small Incision Cataract Surgery (C-SICS).
The aim of the study is to compare functional results and complications of 3 methods of cataract phacoemulsification: bimanual 1.4 mm cataract surgery (B-MICS), coaxial 1.8 mm cataract surgery (C-MICS) and coaxial 2.4 mm small…
- Conditions
- Cataract, Corneal Astigmatism, Corneal Incision Contracture
- Trial name
- MICS (NCT05510869)
- Testing
- Bimanual 1.4 mm microincision cataract surgery (B-MICS) with IOL implantation in a "wound-assisted" technique. In bimanual MICS group a self-sealing 1.4 mm wide incision was created supratemporally, Coaxial 1.8 mm microincision cataract surgery (C-MICS) with IOL implantation with an injector through the 1.8 mm wide incision created temporally., Coaxial 2.4 mm small incision cataract surgery (C-SICS) with IOL implantation with an injector through the 2.4 mm wide incision located temporally.
- Volunteers
- 90 people
- Sponsor
- Medical University of Lodz
Myopia
Safety and Effectiveness of CARE1.02 Spectacle Lens in Myopia Control
China is a major country in myopia, with the highest number of teenagers suffering from myopia. Controlling the progression of myopia and the related complications caused by axial elongation have clinical significance and social…
- Trial name
- NCT05818033
- Testing
- CARE1.02, Single-vision spectacle lens
- Where
- China
- Volunteers
- 796 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Ametropia
Optimization of a Photoretinoscopy Method for Determining the Objective Refraction of Children With a Smartphone/add-on Device in India
The objective is to compare the refractive parameters of the photorefraction prototype device without cycloplegia with the refractive parameters of reference device, an autorefractometer with and without cycloplegia.
- Trial name
- NCT06524115
- Testing
- Comparator device, Closed-field autorefractometer without cycloplegia, Distance visual acuity check using objective refraction without cycloplegia, Comparator device, Closed-field autorefractometer with cycloplegia
- Where
- India
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Characterization of the Central and Peripheral Wavefront Aberration Profile in Pediatric Myopic Subjects
This is a 3-visit, single site, observational clinical study to evaluate the characterization of the central and peripheral wavefront aberration profiles in pediatric myopic subjects.
- Trial name
- NCT06075576
- Testing
- Intervention
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Myopia Progression
The P.A.U.S.E.® Spectacle Study
The goal of this clinical trial is to learn if spectacle lenses using Phase Alteration Utilising Sub Elements (P.A.U.S.E.®) technology works to slow down the rate of myopia progression in myopic children.
- Trial name
- NCT06577948
- Testing
- Single vision spectacle lens, P.A.U.S.E. spectacle lens 1, P.A.U.S.E. spectacle lens 2
- Where
- Vietnam
- Volunteers
- 205 people
- Sponsor
- nthalmic Pty Ltd
Myopia, Progressive
Management of Myopia in University Students Using Dual Focus Soft Contact Lenses
The purpose of the study is to quantify the effectiveness of Coopervision MiSight contact lenses in slowing the rate of myopia progression in university students.
- Trial name
- MoMUS (NCT05955638)
- Testing
- MiSight contact lenses, Proclear contact lenses
- Where
- 2 sites in United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Bradford
Refractive Errors, Myopia
Clinical Performance Assessment of Two Silicone Hydrogel Daily Disposable Contact Lenses
The purpose of this study is to assess the overall clinical performance of a contact lens made with a modified manufacturing process.
- Trial name
- NCT05725317
- Testing
- LID220365 contact lens, LID006961 contact lens
- Where
- 7 sites in United States
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Myopia
Base Curves of Bandage Contact Lenses and Their Effects on Post Trans-PRK Vision and Pain
The objective of this study was to investigate the impact of employing bandage contact lenses with a base curve of 8.4 mm versus 8.8 mm on visual recovery following Trans-PRK in patients characterized by steep corneas and high…
- Trial name
- NCT06393855
- Testing
- single-step Trans-PRK, Placing a bandage contact lens on the cornea, with an 8.4-mm base curve in right eye and one with an 8.8-mm base curve in the left eye., Placing a bandage contact lens on the cornea,A contact lens placed on the cornea, with an 8.8-mm base curve in right eye and one with an 8.4-mm base curve in the left eye.
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Dongyang People's Hospital
Cataract
Femtosecond Laser-assisted Arcuate Incisions Versus Manual Arcuate Incisions Outcomes
This study is designed to compare the effectiveness of LenSx laser arcuate relaxing incisions vs. manual (blade) arcuate relaxing incisions in patients with low, but significant, levels of astigmatism.
- Trial name
- NCT04126174
- Testing
- femtosecond laser system arcuate corneal incision, Manual LRI
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Gainesville Eye Associates
Refractive Errors
Patients' Satisfaction After LASIK
The aim of this study is to evaluate the level of satisfaction, functional vision and quality of life outcome of patients after LASIK surgery.
- Trial name
- NCT04109040
- Testing
- slit lamp
- Volunteers
- 50 people
- Sponsor
- Assiut University
Refractive Errors
Bifocal Lenses In Nearsighted Kids
This study will evaluate the use of two different bifocal contact lens add powers to prevent further nearsighted progression in children ages 7 to 11 years old.
- Trial name
- BLINK (NCT02255474)
- Testing
- Biofinity Multifocal D +1.50 add, Biofinity Multifocal D +2.50 add, Biofinity
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- Ohio State University
Presbyopia
Visual Performance of Dailies Total1 Multifocal and Acuvue Oasys Max 1-Day Multifocal in Presbyopic Lens Wearers
The purpose of this study is to measure the logMAR visual acuity when presbyopic soft lens wearers are fit with Dailies Total1 Multifocal and ACUVUE OASYS MAX 1-DAY Multifocal.
- Trial name
- GIRAFFE (NCT06369987)
- Testing
- Deleficon A (multifocal), Senofilcon A (multifocal)
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
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