Clinical trials: Error, Refractive
Myopia
Refitting Somofilcon A Sphere Contact Lens Wearers Into Fanfilcon A Sphere Lenses for 4-Weeks of Wear
The aim of this subject-masked prospective study is to evaluate the clinical performance of habitual wearers of Clariti Elite sphere lenses after a refit with Avaira Vitality sphere lenses.
- Trial name
- NCT03974802
- Testing
- somofilcon A contact lens, fanfilcon A contact lens
- Where
- Mexico
- Volunteers
- 41 people
- Sponsor
- CooperVision, Inc.
Corneal Astigmatism
Treatment of Vision Disturbances Due to Corneal Irregularities by Trans-epithelial Optical Phototherapeutic Keratectomy (TE-oPTK)
This study sets out to evaluate the EpiMaster application software for use in predicting the refractive change induced by a trans-epithelial phototherapeutic keratectomy (TE-PTK) procedure in eyes with irregularly irregular…
- Trial name
- NCT03841253
- Testing
- Trans-epithelial PTK, Trans-epithelial PTK (retrospective data collection), EpiMaster Application Software
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- London Vision Clinic
Presbyopia
Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia
Safety and efficacy of POS in participants with presbyopia
- Trial name
- VEGA-3 (NCT06542497)
- Testing
- 0.75% phentolamine ophthalmic solution
- Where
- 39 sites in United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Opus Genetics, Inc
Hyperopia, Amblyopia
Effect of Peripheral Defocus on Axial Growth in Hyperopes
Hyperopia, also known as farsightedness, is a common type of refractive error where distant objects may be seen more clearly than objects that are near.
- Conditions
- Hyperopia, Amblyopia, Anisohyperopia
- Trial name
- NCT02686879
- Testing
- Multifocal contact lenses, Single vision contact lenses
- Where
- 2 sites in United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Aston University
Refractive Error, Glaucoma
A Post-market Clinical Study to Collect Safety and Performance Data on Johnson & Johnson Surgical Vision Products
Retrospective collection of data from medical records, multicenter, post-market clinical follow-up study.
- Conditions
- Refractive Error, Glaucoma, Cataracts, Clear Lens Exchange
- Trial name
- NCT05394324
- Testing
- Intervention
- Where
- 13 sites in United States, Germany and 1 more
- Volunteers
- 1,674 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Refractive Errors
Clinical Characterization of an Investigational Soft Silicone Hydrogel Contact Lens
The primary objective of this study is to evaluate the overall clinical performance of an investigational silicone hydrogel contact lens over 2 weeks of daily wear.
- Trial name
- NCT04631796
- Testing
- Lehfilcon A contact lenses, Multipurpose disinfection solution
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Cataract, Presbyopia
Retrospective Clinical Investigation of the Safety and Performance of 640PM Trifocal IOL Implantation in Patients With Cataract and/or Ametropia (Hyperopia, Myopia) and/or Presbyopia
The clinical investigation objective is to evaluate safety and performance outcomes of trifocal IOL implantation to improve vision in patients with cataract and/or ametropia (hyperopia, myopia) and/or presbyopia.
- Conditions
- Cataract, Presbyopia, Hyperopia, Myopia
- Trial name
- NCT05735990
- Testing
- Intraocular lens
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract Senile, Astigmatism
Accuracy of Topography Guided Automatic Marking of the Intraocular Lens (IOL) -Axis
In cataract surgery, the opaque lens is replaced by an artificial intraocular lens. The procedure also allows for correction of an refractive error such as myopia, hyperopia or astigmatism.
- Trial name
- NCT05750862
- Testing
- Marking of the intended axis of IOL-Implantation manually with an ink and marking device on the surface of the eye
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Frank Bochmann
Myopia, Phototherapy
Violet Light for the Suppression of Myopia
The study explores the suppression of myopia via violet light.
- Trial name
- NCT06110520
- Testing
- Violet Light Lamp, White Light Lamp
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Myopia
Two Week Cross-Over Study Comparing Two Daily Disposable Contact Lenses
This study seeks to evaluate and compare the clinical performance of two daily disposable soft contact lenses, Proclear 1 Day and 1-Day Acuvue Moist.
- Trial name
- NCT01155323
- Testing
- etafilcon A, omafilcon A
- Where
- Singapore
- Volunteers
- 118 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lenses, Presbyopia
Clinical Performance of Verofilcon A Toric Contact Lenses
The goal of this clinical trial is to [primary purpose: is to determine if Total30 Multi focal toric conntact lensesare comfortable and the willigness for those who have previously worn reusable toric contact lenses are willing…
- Trial name
- NCT07586982
- Testing
- Total 30 multi foric contact lenses
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Presbyopia
Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia
This is a one-day, randomized, double-masked, single-center evaluation of the efficacy and safety of PRX-100 ophthalmic solution compared to placebo in 20 subjects (randomized 4:1, PRX-100:placebo) to evaluate the safety of…
- Trial name
- NCT02554396
- Testing
- PRX-100
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- LENZ Therapeutics, Inc
Myopia
Assessment of Bifocal and Prismatic Bifocal Spectacles for Myopia Control in Children
1. To determine if the effect of near-addition lenses (bifocals) is more prominent for children with high myopia progression. 2.
- Trial name
- NCT00787579
- Testing
- Bifocal spectacles, Prismatic bifocal spectacles
- Where
- Canada
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Acute Clinical Evaluation of Multi-purpose Solutions (MPS) in Soft Contact Lens Wearers
The purpose of this study was to clinically evaluate lens care solutions used with soft contact lenses.
- Trial name
- NCT00929487
- Testing
- Contact lens multi-purpose solution, Saline/blister pack solution, Contact lenses
- Where
- United Kingdom
- Volunteers
- 278 people
- Sponsor
- Alcon Research
Age Related Cataracts, Astigmatism
Femtosecond Laser-assisted Astigmatism Treatment
The investigational device is an approved femtosecond laser (FSL) device with an integrated imaging system to perform certain steps of the cataract procedure including arcuate incisions (AI) correcting astigmatism, also referred…
- Trial name
- FLAAT (NCT04321226)
- Testing
- Femtosecond Laser guided Arcuate Keratotomy
- Where
- Austria
- Volunteers
- 130 people
- Sponsor
- Medical University of Vienna
Myopia, Cornea
Euclid Phoenix Lens Design Trial 2
Lens wettability and subjective comfort of Euclid orthokeratology lenses with and without an enhanced coating will be compared in 50 children. Axial elongation will be monitored in pediatric patients who qualify and consent.
- Trial name
- NCT06392607
- Testing
- Euclid orthokeratology (standard coating), Euclid orthokeratology (enhanced coating)
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Euclid Systems Corporation
Myopia
Study of Viziatek ISL™ Refractive Phakic Intra Sulcus Lens for Refraction Adjustment in Blind Volunteers
This is a clinical investigation. A total of up to 5 subjects, but not less than 3 at one investigational site will undergo insertion of the ISL in one eye and will be followed through 6 months postoperative.
- Trial name
- NCT05518344
- Testing
- Viziatek ISL™ (hereinafter referred to as the "ISL") implanted in blind eye.
- Where
- Latvia
- Volunteers
- 4 people
- Sponsor
- Hanita Lenses
Astigmatism
The Clinical Study of Silicone Hydrogel Daily Disposable Stenfilcon A Toric Lens
The aim of this study is to evaluate the clinical performance of stenfilcon A toric lenses compared with etafilcon A toric lenses for astigmatism.
- Trial name
- NCT02801006
- Testing
- stenfilcon A, etafilcon A
- Where
- 2 sites in Japan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Assessment of Lotrafilcon A Contact Lenses
The purpose of this 3-month study is to evaluate subjective responses to an upgraded contact lens.
- Trial name
- NCT01185834
- Testing
- Lotrafilcon A upgrade soft contact lens
- Volunteers
- 118 people
- Sponsor
- CIBA VISION
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
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