Clinical trials: Error, Refractive
Ophthalmic Diseases (Specific Types Not Restricted), Cataract
Research on a New Intelligent Mobile Screening and Diagnosis Pattern for Ocular Diseases
The global distribution of primary ophthalmic medical resources is uneven, and the traditional eye disease screening model has problems such as low efficiency, high cost and limited coverage.
- Conditions
- Ophthalmic Diseases (Specific Types Not Restricted), Cataract, Refraction Error, Diabetic Retinopathy (DR)
- Trial name
- NCT07003165
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
A Multi-Center Study Comparing the Clinical Performance of Two Silicone Hydrogel Lenses Over 1 Month of Daily Wear
A Multi-Center Study Comparing the Clinical Performance of Two Silicone Hydrogel Lenses Over 1 Month of Daily Wear
- Trial name
- NCT01952665
- Testing
- comfilcon A, lotrafilcon B
- Where
- 6 sites in United States
- Volunteers
- 63 people
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
On-Eye Evaluation of Contact Lens Axis Location
The purpose of this study was to evaluate the axis location of toric contact lenses after 3 minutes of wear. During this 1-visit study, each participant wore 3 pairs of study lenses of various design iterations (2-87-1, 2-87-2…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT02100410
- Testing
- Delefilcon A toric contact lens T1, Delefilcon A toric contact lens T2, Delefilcon A toric contact lens T3
- Volunteers
- 50 people
- Sponsor
- Alcon Research
Myopia
Efficacy and Safety of MiSight ® Contact Lenses in Reducing the Progression of Childhood Myopia.
The purpose of the study is to quantify the effectiveness of CooperVision MiSight® (omafilcon A) soft (hydrophilic) contact lens in slowing the rate of progression of juvenile-onset myopia.
- Trial name
- NCT01917110
- Testing
- omafilcon A, Spectacle
- Where
- Spain
- Volunteers
- 79 people
- Sponsor
- CooperVision, Inc.
Myopia
MiSight 1 Day Safety Post-Approval Study
The purpose of this post-approval study is to confirm the safety of daily disposable soft contact lens wear among the intended patient population for the MiSight 1 Day lens in the US.
- Trial name
- NCT05285527
- Testing
- MiSight 1 Day
- Where
- 50 sites in United States, Canada
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Effects of Contact Lens Care Regimens on the Corneal Epithelium
The purpose of this study is to compare the performance of two different contact lens care solutions, specifically their affects on the front surface of the eye.
- Trial name
- NCT00349882
- Testing
- soft contact lens, Marketed multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Cataract Extraction
Microincision Versus Smallincision Combined Surgery
The purpose of this study is to compare refractive outcomes after two different types of combined cataract surgery, namely microinscision cataract surgery and smallincision cataract surgery, and sutureless 23-gauge vitrectomy in…
- Trial name
- NCT01198483
- Testing
- Combined Micro- Surgery, Combined Small-Surgery
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Myopia
Electronic Spectacles Versus Low Dose Atropine in Young Myopes
This is a bilateral, dispensing, masked, randomized clinical trial. Myopic children will be randomly assigned to one of the following: (1) Investigational clinical prototype (CP1) device without atropine, (2) Investigational CP1…
- Trial name
- NCT06034379
- Testing
- eSpectacle Clinical prototype (CP1) device, 0.01% atropine
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Hyperopia, Myopia
A Phase 1/2 Crossover Study to Assess EXP039 for Myopia or Hyperopia
Assess the Safety, Pharmacodynamics, and Efficacy of EXP039 Ophthalmic Solution in Participants with Myopia or Hyperopia
- Trial name
- NCT04883996
- Testing
- 1% EXP039, Saline control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Canyon City Eyecare
Refractive Errors, Myopia
Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
The goal of this observational study is to test whether surgeries for lenses designed to be implanted in the eye to correct refractive error can be done without the need for using viscoelastic substances that are used routinely…
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism, Hypermetropia
- Trial name
- NCT06371079
- Testing
- phakic intraocular lens implantation traditional, phakic intraocular lens implantation reduced OVD
- Where
- Iraq
- Volunteers
- 448 people
- Sponsor
- Loay Abdulmutalib Almusawi
Cataract, Lens Opacities
Clinical Study to Investigate Outcomes of Trifocal Toric IOL POD FT in Asian Eyes
Prospective, controlled, single-surgeon, single-center clinical study to compare visual acuity outcomes to data obtained in a similar study by the same principal investigator on the trifocal IOL POD F (study no.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT03844828
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 100 people
- Sponsor
- Beaver-Visitec International, Inc.
Myopia
Aberration-Free Refraction Correction
In the interest of improving visual quality after LASIK we have designed a multifaceted study to test the theoretical, physical, biomechanical and functional effects of commercial and independently designed aspherical ablation…
- Trial name
- NCT00172913
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Myopia
Impact of Positive & Negative Lens-Induced Defocus on Contrast-Sensitivity in Myopic & Non-Myopic Adults
examines the influence of lens-induced defocus on contrast sensitivity-a crucial aspect of visual performance.Each participant experiences both positive and negative defocus through different lenses, with measurements taken for…
- Trial name
- NCT06753032
- Testing
- Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Myopic Participants, Negative Lens-Induced Defocus Using Spectacle Lenses (-2.00 D) for Myopic Participants, Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Non-Myopic Participants
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Superior University
Hyperopia, Hyperopic Astigmatism
Clinical Investigation of the WaveLight® EX500 Excimer Laser
The purpose of this study is to collect efficacy and safety data on the WaveLight EX500 excimer laser system for the correction of hyperopia with and without astigmatism by laser in situ keratomileusis (LASIK) treatment.
- Trial name
- NCT04805593
- Testing
- WaveLight EX500 excimer laser system, LASIK
- Where
- 5 sites in United States
- Volunteers
- 44 people
- Sponsor
- Alcon Research
Myopia
Dispensing Evaluation of a Prototype Contact Lens and a Marketed Contact Lens
The purpose of this study is to compare visual acuity and redness of eyes between a prototype contact lens and an already marketed contact lens.
- Trial name
- NCT01094743
- Testing
- galyfilcon A prototype lens, lotrafilcon B lens
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
SEED-LVPEI Myopia Study
This randomized clinical trial study aims to investigate the efficacy of novel SEED's EDOF based mid-lens design in controlling the myopia progression in Indian children with these specific objectives: 1.
- Trial name
- SLIMS (NCT04618510)
- Testing
- SEED 1-dayPure EDOF soft contact lens, Single Vision Spectacles
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- L.V. Prasad Eye Institute
Myopia
Polarization Sensitive Optical Coherence Tomography
The purpose of the study is to use the polarization sensitive optical coherence tomography (PS-OCT) developed by Singapore Eye Research Institute, to evaluate the potential OCT scleral biomarkers capable of predicting risk of…
- Trial name
- NCT05809674
- Testing
- Polarization sensitive optical coherence tomography (PS-OCT)
- Where
- Singapore
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Singapore Eye Research Institute
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Keratoconus, Astigmatism
Corneal Epithelial and Stromal Thickness Distribution in Keratoconus
The purpose of the study was to identify corneal epithelial- and stromal-thickness distribution patterns in keratoconic eyes using spectral-domain-optical coherence tomography (SD-OCT).
- Trial name
- NCT02023619
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- SynsLaser Kirurgi AS
Myopia
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
- Trial name
- NCT03516357
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
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