Clinical trials: Eruption
Dermatologic Complications, Unspecified Adult Solid Tumor, Protocol Specific
Regenecare® Wound Gel in Treating Rash in Patients Receiving Cetuximab or Other Epidermal Growth Factor Receptor Inhibitor Therapy for Cancer
RATIONALE: Regenecare® wound gel may help relieve pain and itching in patients who develop an acne-like rash while undergoing treatment with cetuximab or another epidermal growth factor receptor inhibitor for cancer.
- Trial name
- NCT00498992
- Testing
- collagen/aloe vera/vitamin E/lidocaine topical hydrogel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ingalls Memorial Hospital
Acne Vulgaris
Evaluation of Topical Dutasteride as a Potential New Therapy for Facial Acne Vulgaris Versus the Triple Combination Therapy (Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel)
Acne vulgaris (AV) is one of the most prevalent dermatological conditions worldwide, affecting approximately 85% of adolescents and young adults between the ages of 12 and 24 years .While acne is often self-limiting, it can have…
- Trial name
- NCT07421804
- Testing
- topical dutasteride
- Volunteers
- 50 people
- Sponsor
- Assiut University
Oral Lichen Planus, Erosive Lichen Planus
Photobiomodulation, Photodynamic Therapy, and Clobetasol in the Treatment of Oral Lichen Planus.
This study aims to compare three treatment approaches for the erosive form of oral lichen planus, a chronic inflammatory condition that often causes pain, impaired oral function, and frequent relapses.
- Conditions
- Oral Lichen Planus, Erosive Lichen Planus, Mucosal Lesions
- Trial name
- NCT07278999
- Testing
- Photobiomodulation using 635 nm diode laser, Photodynamic therapy - laser mucosal treatment, Clobetasol propionate 0.05 percent topical application
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Silesia
Acne Vulgaris
To Compare the Efficacy and Safety of Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel of CHL Versus DUAC® Gel
This is an Randomized, Double-blind, Multicentric, Parallel-group, Active and Placebo Controlled, Three Arm Clinical Study. The main objective is to evaluate bioequivalence of Test formulation (Clindamycin Phosphate 1.2%/Benzoyl…
- Trial name
- NCT02005666
- Testing
- Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel, DUAC® Gel
- Where
- 36 sites in United States, India
- Volunteers
- 850 people
- Sponsor
- Zydus Lifesciences Limited
Lichen Planus, Oral
Treatmant of Oral Lichen Planus With Lycopene
the purpose of this study was to evaluate that if lycopene, a potent antioxidant can be used in the treatment of oral lichen planus.
- Trial name
- NCT00656214
- Testing
- Lycopene
- Where
- India
- Volunteers
- 30 people
- Sponsor
- College of Dental Sciences, India
Acne Vulgaris
A Clinical In-Use Evaluation to Assess the Tolerability and Efficacy of a Moisturizer on Acne Prone Skin
The objective of this study is to evaluate the tolerance and efficacy of a facial moisturizer in subjects with mild to moderate acne vulgaris over a 4-week treatment period.
- Trial name
- NCT07224633
- Testing
- Use of Barrier Building Moisturizer
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Acne Vulgaris
Effectiveness and Tolerance of Effaclar Serum in Women With Mandibular Acne
The role of "dermocosmetics" in acne management is increasingly important, as many patients and even physicians now resort to them as first-line management in mild-to-moderate acne.
- Trial name
- NCT05457621
- Testing
- Effaclar serum
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Skin Rash
Histological Characterization and Differentiation of Rash From Other Epidermal Growth Factor Receptor (EGFR) Inhibitors
The purpose of this study is to characterize the microscopic findings of skin rash associated with the use of chemotherapeutic anticancer agents known as epidermal growth factor inhibitors (EGFRIs).
- Trial name
- NCT00709878
- Testing
- Skin Biopsy of Skin Rash Secondary to EGFRI Use
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Northwestern University
Acne
Efficacy and Safety of IDP-121 and IDP-121 Vehicle Lotion in the Treatment of Participants With Acne Vulgaris
The objective of this study was to evaluate the efficacy, safety, and tolerability of a once daily topical application of IDP-121 Lotion compared with its vehicle (IDP-121 Vehicle Lotion) in participants with moderate to severe…
- Trial name
- NCT02932306
- Testing
- IDP-121 Lotion, IDP-121 Vehicle Lotion
- Where
- 39 sites in United States
- Volunteers
- 820 people
- Sponsor
- Bausch Health Americas, Inc.
Altered Passive Eruption of Teeth
Gummy Smile and Altered Passive Eruption Prevalence
This observational epidemiological study aims to assess the prevalence of gummy smile and altered passive eruption in a young adult population, with a focus on the second sextant.
- Trial name
- NCT07548398
- Testing
- Clinical assessment
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
EGFR Inhibitor-associated Rash
TAR-0520 Gel in EGFR Inhibitor-induced Folliculitis
A Phase II, multicentric, randomized, double-blind, placebo-controlled, parallel- group trial to confirm the good safaty profile and to explore the preventive effect of topically applied TAR-0520 gel on folliculitis developed in…
- Trial name
- NCT06818058
- Testing
- Brimonidine tartrate Gel
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Tarian Pharma
Acne Vulgaris
A Study of a Hydrocolloid Bandage on Pimples
The purpose of this study is to evaluate the effectiveness and tolerability of a hydrocolloid bandage on pimples when used overnight for one week.
- Trial name
- NCT05012735
- Testing
- Study Cleanser (Neutrogena Ultra Gentle Daily Cleanser with Pro Vitamin B5), Prototype Ultrathin Hydrocolloid Bandage
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Health Behavior
Oral Sialic Acid Product Beauty Efficacy Test
Evaluate and compare the effects on female facial skin of oral placebo (Product A), N-acetylneuraminic acid (Product B), and ACAI-PLUS (Product C) after 28, 56, and 84 days under normal usage conditions.
- Trial name
- NCT07640321
- Testing
- Oral N-acetylneuraminic acid, OralACAI-PLUS
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Wuhan CASOV Green Biotech Co., Ltd
Meningitis, Meningococcal, Meningococcal Sepsis
Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA.
A fever and a non-blanching rash is a relatively common reason for a child to attend an emergency department. A fever and a non-blanching rash can be an early sign of a life-threatening infection known as meningococcal disease.
- Conditions
- Meningitis, Meningococcal, Meningococcal Sepsis, Meningococcal Disease, Meningococcal Infections
- Trial name
- PIC (NCT03378258)
- Where
- United Kingdom
- Volunteers
- 1,329 people
- Sponsor
- Belfast Health and Social Care Trust
Acne Vulgaris
A Study Comparing Tazarotene Cream 0.1% to Tazorac® and Both to a Placebo Control in the Treatment of Acne Vulgaris
The purpose of this study is to evaluate the therapeutic equivalence and safety of Tazarotene Cream 0.1% and Tazorac® (tazarotene cream 0.1%).
- Trial name
- NCT02411955
- Testing
- Tazarotene Cream 0.1%, Tazorac®
- Volunteers
- 1,077 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Vulgaris
Studying the Skin Microbiome and the Potential of a Topical Probiotic Cream for Patients With Acne
In this study the topical use of cream with live probiotic bacteria was evaluated for its efficacy in reducing acne symptoms and its effect on the skin microbiota on patients with acne.
- Trial name
- NCT03469076
- Testing
- YUN ACN Cream
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Vulvar Lichen Sclerosus, Vulvar Atrophy
Efficacy of Collagendep in Reducing Vulvar Dryness in Patients With Lichen Sclerosus Treated With Fat Grafting
This randomized, interventional study evaluates the efficacy of Collagendep Pink Beauty, an oral nutritional supplement, in reducing vulvar dryness in women with Genital Lichen Sclerosus (VLS) who are undergoing fat grafting…
- Trial name
- Collagendep (NCT07450625)
- Testing
- Autologous Fat Grafting (Lipofilling), Collagendep Pink Beauty
- Volunteers
- 40 people
- Sponsor
- San Gallicano Dermatological Institute IRCCS
Acne Vulgaris
Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin
The use of oral antibiotics alone to treat inflammatory acne provides little to no long term therapeutic benefit. Acne relapse rates can be reduced by using topical tretinoin 0.01% in conjunction with minocycline, thereby…
- Trial name
- NCT00240513
- Testing
- Minocycline, Minocycline plus tretinoin
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Derm Research @ 888 Inc.
Acne Vulgaris
Evaluate the Efficacy and Safety of Intense Pulsed Light Filters Combined With Oral Medication in the Treatment of Acne
1. Acne is a chronic inflammatory disease involving the hair follicles and sebaceous glands, characterized by acne, papules, pustules, nodules, and cysts.
- Trial name
- NCT04433143
- Testing
- Minocycline hydrochloride capsules were taken orally
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Gang Wang
Acne Vulgaris
Cultural Differences in Treatment Preferences and Perceptions of Acne
This study will use a survey to examine relationships between culture, race, and ethnicity with treatment preferences and perceptions for acne vulgaris.
- Trial name
- CDTPPA (NCT03192163)
- Testing
- Survey
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- Northwestern University