Clinical trials: Erythema
Healthy Subjects, Male or Female, of 18-60 Years Old, With Phototype I, II or III, Not Pre-treated/Pre-protected Skin
Performance of Different Application Regimens of ACTINICA® on Protection From UVR-induced Erythema After One Day of Sun Exposure in Fair-skinned Healthy Subjects.
Study objective To assess the performance of different application regimens of Actinica® on protection from UV rays-induced erythema throughout 1 day of sun exposure in fair-skinned healthy subjects (phototype I to III).
- Trial name
- NCT02251756
- Testing
- Actinica, 0.8 mg/cm2, 1 application, Actinica, 0.8 mg/cm2, 2 applications, Actinica, 2 mg/cm2, 1 application
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Relapsing-Remitting Multiple Sclerosis (RRMS)
Brimonidine Tartrate for the Treatment of Injection Related Erythema
The primary objective of this study is to evaluate the Injection Related Erythema (IRE) mitigation effect of a single administration of brimonidine tartrate in comparison with a vehicle gel (placebo).
- Trial name
- BRITE (NCT02568111)
- Testing
- peginterferon beta-1a, brimonidine tartrate, Vehicle Gel
- Sponsor
- Biogen
Seasonal Allergic Rhinitis
A Phase III Efficacy Study of the Symptomatic Treatment of Seasonal Allergic Rhinitis With Bilastine
The objective of the study was to determine the efficacy and tolerability of 20 mg of Bilastine, compared to Desloratadine and placebo for the treatment of Seasonal Allergic Rhinitis.
- Trial name
- NCT01108783
- Testing
- Bilastine, Desloratadine
- Volunteers
- 720 people
- Sponsor
- Faes Farma, S.A.
Facial Subcutaneous Fullness, Subcutaneous Fat Accumulation
Efficacy and Safety of High-Dose Oral 35 kDa Hyaluronan for Aesthetic Improvement
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of high-dose oral 70 kDa hyaluronan (HA35) for aesthetic improvement.
- Conditions
- Facial Subcutaneous Fullness, Subcutaneous Fat Accumulation, Facial Inflammatory Erythema, Dull Skin
- Trial name
- HA35-ORAL (NCT07583108)
- Testing
- High-Dose Oral 35 kDa Hyaluronan (HA35)
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nakhia Impex LLC
Rosacea, Erythema
An Evaluation of the Reduction in Erythema in Adult Patients With Moderate to Severe Persistent Facial Erythema Associated With Rosacea
the study will measure the decrease in redness on the face of rosacea subjects
- Trial name
- NCT03352323
- Testing
- Oxymetazoline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Padagis LLC
Angiofibroma of Face, Tuberous Sclerosis
Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex
The objective of this study is to evaluate the safety and efficacy of sirolimus (0.2% and 0.4% formulations) and its vehicle when applied topically once daily for 12 weeks for the treatment of cutaneous angiofibromas in pediatric…
- Trial name
- NCT03363763
- Testing
- Sirolimus 0.2%, Sirolimus 0.4%
- Where
- 8 sites in United States, China
- Volunteers
- 24 people
- Sponsor
- Aucta Pharmaceuticals, Inc
Erythema, Rosacea
A Long-Term Safety and Efficacy Study AGN-19920 in Patients With Persistent Erythema Associated With Rosacea
This study will evaluate the long-term safety and efficacy of oxymetazoline hydrogen chloride (HCL) Cream 1.0% (AGN-199201) in patients with persistent erythema associated with rosacea.
- Trial name
- NCT02095158
- Testing
- Oxymetazoline HCL Cream 1.0%
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- Allergan
Breast Cancer, Radiation Dermatitis
A DB Randomized Study of R1 and R2 WaterJel / AloeVera Jell in Prevention of Radiation Dermatitis in Breast Cancer
The purpose of this study is to evaluate the effects of topical R1 and R2 for prophylaxis of acute radiation dermatitis in patients with breast cancer receiving radiotherapy.
- Conditions
- Breast Cancer, Radiation Dermatitis, Erythema
- Trial name
- NCT01597921
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Water-Jel
Female, Redness
Serum Instant Anti-Redness Efficacy Clinical Study
This study is a mono-centric, om-site use, random half-face application, blank control study. 64 female adult subjects will be enrolled and divided into 2 groups in the study, recruited according to inclusion and non-inclusion…
- Trial name
- NCT07058701
- Testing
- Investigational Serum, Standard Cleanser, Infrared Light for Redness Induction on Face
- Where
- China
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Erythema, Sensitisation
Irritation Potential of Omeza Collagen Matrix Using Modified HRIPT
The primary objective of this study was to assess the sensitization potential of Omeza Collagen Matrix compared to that of a negative control based on a Modified Human Repeat Insult Patch Test.
- Trial name
- NCT04510675
- Testing
- Test Article, Negative Control
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Omeza, LLC
Plaque Psoriasis
A Single-Center Exploratory Study to Assess the Activity of CRx-197-002 in Plaque Psoriasis
This will be a phase 2a single-center, randomized, blinded, vehicle-controlled exploratory study to assess the activity and safety of CRx-197 in subjects with plaque psoriasis.
- Trial name
- 197-002 (NCT00796211)
- Testing
- CRx-197, Nortriptyline, Calcipotriol
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Zalicus
Hypersensitive, Reactive and Intolerant Skin
IN-USE TOLERANCE STUDY UNDER DERMATOLOGICAL AND OPHTHALMOLOGICAL CONTROLS AND EFFICACY ASSESSMENT (Face Balm)
The aim of this study is to assess the dermatological and ophthalmological tolerance of the investigational product Baume visage / Face balm RV4942A - RY1985 after 21 days of twice daily use on the study areas, under normal…
- Conditions
- Hypersensitive, Reactive and Intolerant Skin, Redness-prone Skin, Stinger Subjects
- Trial name
- NCT05171556
- Testing
- Cosmetic product
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Rosacea, Redness
Evaluation of the Efficacy and Tolerance of Two Cosmetic Products in Subjects With Rosacea
Multicentric and double-blind randomised comparative clinical study in Argentina and Brazil. Under dermatological and ophthalmological control 4 visits: inclusion [Day(D)0], D28, D56, D84 Ethical committee required.
- Conditions
- Rosacea, Redness, Telangiectasia, Flushing
- Trial name
- NCT06582043
- Testing
- SCARCr tester 1
- Where
- 2 sites in Argentina, Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NAOS Argentina S.A.
Rosacea
Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea
The purpose of this vehicle controlled study is to evaluate the efficacy and safety of CD07805/47 gel 0.5% applied topically once daily (QD) for 4 weeks, and CD07805/47 gel 0.18% applied topically once daily (QD) or twice daily…
- Trial name
- NCT01174030
- Testing
- CD07805/47 Gel, Vehicle Gel
- Where
- 20 sites in United States
- Volunteers
- 269 people
- Sponsor
- Galderma R&D