Clinical trials: Erythema
Erythema
Melanin Index in Those With Fitzpatrick Skin Phototypes I-VI
The "gold standard" method of assessing skin pigmentation is spectrophotometry; however, even as early as 1961 the potential for confounding by dilatation of blood vessels was recognized.
- Trial name
- Melanin Index (NCT01124513)
- Testing
- Induced Erythema
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hypersensitive, Reactive and Intolerant Skin
IN-USE TOLERANCE STUDY UNDER DERMATOLOGICAL AND OPHTHALMOLOGICAL CONTROLS AND EFFICACY ASSESSMENT (Face Cream)
The aim of this study is to assess the dermatological and ophthalmological tolerance of the investigational product Crème visage / Face cream RV4941A - RY1987 after 21 days of twice daily use on the study areas, under normal…
- Conditions
- Hypersensitive, Reactive and Intolerant Skin, Redness-prone Skin, Stinger Subjects
- Trial name
- NCT05165420
- Testing
- Cosmetic product
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Rosacea
Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea
Rosacea is a common skin condition associated with easy blushing and red face; many patients with rosacea react to sunlight with increased redness.
- Trial name
- NCT06312813
- Testing
- Imipramine, Amitriptyline, Vehicle
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Wright State University
Graft vs Host Disease, Congenital Aniridia
Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis Implantation
The ARGOS-IO pressure sensor is intended to be implanted in the human eye in combination with Boston Keratoprosthesis (BKPro) surgery and to remain in place indefinitely.
- Conditions
- Graft vs Host Disease, Congenital Aniridia, Chemical Burns, Stevens-Johnson Syndrome
- Trial name
- NCT02945176
- Testing
- ARGOS-IO system
- Where
- 2 sites in Germany
- Volunteers
- 13 people
- Sponsor
- Implandata Ophthalmic Products GmbH
Melasma
Effectiveness and Safety of Intradermal Tranexamic Acid Injection as An Adjunctive Treatment for Melasma in Skin Type IV - V
A double-blind, randomized, split-face controlled trial of 34 female patients with melasma was conducted. All subject were randomized to receive either intradermal tranexamic acid or placebo injection on the right or the left…
- Trial name
- NCT05236569
- Testing
- Tranexamic acid injection, Injection Water
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Erythema Migrans of Lyme Disease
Effect of Saccharomyces Boulardii CNCM I-745 on Gut Microbiota in Patients Undergoing Antibiotic Therapy (in the Context of Erythema Migrans (Early Skin Form of Lyme Borreliosis))
The aim of this study is to assess the effect of Saccharomyces boulardii CNCM I-745 on gut microbiota in patients undergoing antibiotic therapy (in the context of erythema migrans (early skin form of Lyme borreliosis)).
- Trial name
- SUBLYME (NCT06451913)
- Testing
- Amoxicillin + Saccharomyces boulardii CNCM I-745, Stool samples, BSFS : Bristol Stool Form Scale
- Where
- Slovenia
- Volunteers
- 120 people
- Sponsor
- Biocodex
Stevens-Johnson Syndrome
Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye
The purpose of this study is to evaluate the efficacy of 0.05% cyclosporin ophthalmic emulsion (Restasis) in patients with Stevens-Johnson syndrome that have dry eyes by subjective symptoms and signs.
- Trial name
- NCT01488396
- Testing
- 0.05%cyclosporin eye drop
- Where
- Thailand
- Volunteers
- 31 people
- Sponsor
- Mahidol University
Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis
Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis
This is a prospective, multicenter cohort observational; study to compare treatment outcomes in patients admitted to the hospital with Stevens-Johnsons Syndrome/Toxic Epidermolysis, aiming to assess the utility of medical…
- Conditions
- Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, Drug Reaction
- Trial name
- NCT03585946
- Testing
- Site specific standard of care comparison
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pressure Ulcer, Diabetes Mellitus Type 2
The Effect of Shear- Force at the Skin in Patients With Diabetes Mellitus
1. The objective of this study is to acquire knowledge about the development of reactive hyperaemia and inflammatory responses of the skin after shear- force and pressure loading.
- Conditions
- Pressure Ulcer, Diabetes Mellitus Type 2, Charcot- Osteoarthropathy
- Trial name
- NCT02348294
- Testing
- Shear- force 19 newton and 3,9 kpa pressure for half an hour
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Lichen Planus Pigmentosus, Erythema Dyschromicum Perstans
The Efficacy of Tranexamic Acid in the Treatment of Lichen Planus Pigmentosus and Erythema Dyschromicum Perstans
There are currently no effective treatments for lichen planus pigmentosus (LPP) and erythema dyschromicum perstans (EDP). Tranexamic acid, which may downregulate pigmentation through a reduction in plasmin, has been shown to…
- Conditions
- Lichen Planus Pigmentosus, Erythema Dyschromicum Perstans, Ashy Dermatosis of Ramirez
- Trial name
- NCT04233749
- Testing
- Tranexamic acid tablets
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Henry Ford Health System
Stevens-Johnson Syndrome, Corneal Blindness
Infliximab to Improve Retention of the Boston Keratoprosthesis in Patients After Stevens Johnson Syndrome/ Toxic Epidermal Necrolysis (SJS/TENS)
The proposed study is intended to test the idea, based upon current knowledge of the biology and physiology of corneal ulceration in SJS/TENS patients who receive a keratoprosthesis, and on the known effects of infliximab on…
- Trial name
- NCT01256489
- Testing
- Infliximab
- Where
- United States
- Sponsor
- Massachusetts Eye and Ear Infirmary
Palmar and Plantar Erythema, Numbness of the Four Limbs
Traditional Chinese Medicine Treatment for Capecitabine-Related Hand-Foot Syndrome
This study is a prospective, single-center, randomized, parallel-group, open-label clinical trial titled "Intervention with the 'Xu Xue Tong Luo Traditional Chinese Medicine Compound for Capecitabine-Related Hand-Foot Syndrome."…
- Conditions
- Palmar and Plantar Erythema, Numbness of the Four Limbs, Pain in the Distal Extremities, Peeling of the Soles and Palms
- Trial name
- NCT07883642
- Testing
- Twelve-Ingredient Prepared Sichuan Aconite Hand and Foot Bath, Standard Basic Nursing Interventions
- Volunteers
- 7 people
- Sponsor
- Emeishan Hospital of Traditional Chinese Medicine
Stevens - Johnson Syndrome
G-CSF in the Treatment of Toxic Epidermal Necrolysis
NeupoNET aims to evaluate interest of G-CSF in the treatment of Toxic Epidermal necrolysis. This is a prospective randomized controlled trial.
- Trial name
- NeupoNET (NCT02739295)
- Testing
- recombinant granulocyte - colony stimulating factor, NaCl 0.9%
- Where
- 2 sites in Belgium
- Volunteers
- 10 people
- Sponsor
- University of Liege
Perianal Abscess
Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces
This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery.
- Trial name
- NCT07155356
- Testing
- Red light exposure, Red-blue light exposure
- Where
- China
- Volunteers
- 222 people
- Sponsor
- The Affiliated Hospital of Putian University
Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum
Nutritional and Metabolic Management of Toxidermia Patients Requiring Intensive Care (TEN Metabolism)
Retrospective observational cohort study including all patients admitted for toxidermia (Lyell syndrome, Stevens-Johnson Syndrome (SJS), or other extensive skin destruction) to the Burn unit of the adult ICU of the Lausanne burn…
- Trial name
- TEN metabolism (NCT05320653)
- Testing
- Medical nutrition
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Post Procedural Erythema
Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures
Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.
- Trial name
- NCT06477172
- Where
- 42 sites in United States, Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Acorn Biolabs Inc.
Nociceptive Pain, Musculoskeletal Pain
Clinical Trial of the invisaRED® IR REHAB Device When Used as an Adjunctive Therapy for Nociceptive Musculoskeletal Pain
This is a trial to measure the effectiveness and safety of the invisa-RED® IR REHAB device. The researchers will compare the muscle and joint pain relief of participants who are treated with the real machine, to those treated…
- Trial name
- NCT06393088
- Testing
- IR REHAB
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- IR Technology, LLC
Erythema, Rosacea
Study of Inter- and Intra-rater Reliability of the Clinician Erythema Assessment Scale
This is a study to evaluate inter- and intra-rater reliability of the Clinician Erythema Assessment Scale. There is no treatment (intervention) associated with this study.
- Trial name
- NCT01636765
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Allergan
Rosacea, Erythema
AGN-199201 for the Treatment of Erythema With Rosacea
This study will evaluate the safety and efficacy of 3 doses of AGN-199201 once and twice daily compared to vehicle for the treatment of moderate to severe facial erythema associated with rosacea.
- Trial name
- NCT01735201
- Testing
- AGN-199201 Dose A, AGN-199201 Dose B, AGN-199201 Dose C
- Where
- United States
- Volunteers
- 357 people
- Sponsor
- Allergan
Wrinkle Appearance, Skin Pigment
Cosmetic Effects of Topical Acetyl Zingerone
Cosmeceuticals are an emerging market within dermatology and the growth of natural products and derivatives of natural products has accelerated in use within the field.
- Conditions
- Wrinkle Appearance, Skin Pigment, Erythema, Side Effect
- Trial name
- NCT03530787
- Testing
- Acetyl Zingerone Topical Cream, Topical cream
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of California, Davis