Clinical trials: Esophageal Fistula
AF - Atrial Fibrillation, Complication
Esophageal Protection Study: A Multicenter Study
Atrial fibrillation (AF) is a common debilitating heart rhythm condition that can cause heart failure and negatively impact a patient's outlook in terms of symptoms and disability.
- Conditions
- AF - Atrial Fibrillation, Complication, Atrio-Esophageal Fistula
- Trial name
- NCT04577859
- Testing
- ensoETM. Esophageal cooling during AF ablation, Esophageal temperature monitoring probe
- Where
- 6 sites in United States, United Kingdom
- Volunteers
- 152 people
- Sponsor
- Advanced Cooling Therapy LLC, d/b/a Attune Medical
Esophageal Squamous Cell Carcinoma (ESCC), Esophageal Fistula
Standardized Management of Esophageal Fistula in Esophageal Squamous Cell Carcinoma
This prospective, multi-center, observational registry study (PKU-ESCC-EF) aims to evaluate the safety and effectiveness of a standardized diagnosis and treatment protocol for esophageal fistula (EF) in patients with advanced…
- Trial name
- PKU-ESCC-EF (NCT07353541)
- Testing
- Standardized Management Protocol for Esophageal Fistula
- Volunteers
- 32 people
- Sponsor
- Peking University Cancer Hospital & Institute
Esophageal Fistula, Esophageal Perforation
Endoscopic Management of Esophageal Wall Defects
The study aim at comparing outcomes from the implementation of various endoscopic closure techniques including stenting and suturing on the healing and resolution of esophageal wall defects.
- Trial name
- NCT04571541
- Testing
- Stenting
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Cardiac Arrhythmias, Atrial Fibrillation
Randomized Study on the Effect of Oesophageal Temperature on the Incidence of Esophageal Lesions After AF Ablation
It's a randomized pilot study to evaluate the incidence of esophageal thermal injury after left atrial ablation for the treatment of atrial fibrillation according to three different strategies of esophageal temperature…
- Conditions
- Cardiac Arrhythmias, Atrial Fibrillation, Esophageal Ulcer
- Trial name
- NCT03645070
- Testing
- multipolar and self expandable thermometer, Single probe thermometer
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Obesity, Obesity, Morbid
Luso-Cor Stent Compared to Other Endoscopic Techniques for Management of Fistulas and Anastomotic Dehiscences(ES-LCCE-UDFM)
The global prevalence of obesity has prompted an increase in bariatric surgery, which is the only management strategy that provides long-term weight loss and improvement of obesity-related diseases.
- Conditions
- Obesity, Obesity, Morbid, Esophageal Cancer, Esophageal Neoplasms
- Trial name
- ES-LCCE-UDFM (NCT06862479)
- Testing
- Endoscopic management of fistulas with stents or vacum therapy
- Where
- Portugal
- Volunteers
- 180 people
- Sponsor
- Unidade Local de Saúde Santa Maria
Esophageal Atresia, Tracheoesophageal Fistula
Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair
This trial will compare the effectiveness of two common surgical practices for Type C esophageal atresia repair: esophageal atresia (EA) with distal tracheoesophageal fistula (TEF).
- Trial name
- TEF (NCT03730454)
- Testing
- Transanastomotic Tube (5FR), No Transanastomotic Tube
- Where
- 10 sites in United States
- Volunteers
- 142 people
- Sponsor
- Phoenix Children's Hospital
Atrial Fibrillation, Esophageal Perforation
Esophageal Injury of a Tip CF Sensing Ablation Catheter for HP-SD of Paroxysmal and Persistent AF (ESO-SAFE-HP-RF)
This pilot, prospective, interventional, monocentric, independent, and no-profit clinical trial aims to investigate and evaluate the proportion, acute and chronic characteristics, and outcomes of esophageal thermal injury (ETI)…
- Conditions
- Atrial Fibrillation, Esophageal Perforation, Esophageal Fistula
- Trial name
- ESO-SAFE-HP-RF (NCT05758805)
- Testing
- mini-invasive esophagoscopy, HP-SD AF ablation by a CF sensing catheter
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Quovadis Associazione
Esophageal Fistula, Esophageal Neoplasms
Removal of the Evolution® Esophageal Stent - Fully Covered
The CLARITY study is a clinical trial approved by US FDA to study the removal of the Evolution® Esophageal Stent-Fully Covered in malignant and benign indications.
- Conditions
- Esophageal Fistula, Esophageal Neoplasms, Esophageal Perforation, Esophageal Stenosis
- Trial name
- CLARITY (NCT01900691)
- Testing
- Evolution® Esophageal Stent - Fully Covered
- Where
- 11 sites in United States
- Volunteers
- 130 people
- Sponsor
- Cook Group Incorporated
Acquired Tracheo-esophageal Fistula
Endoscopic Closure of Tracheoesophageal Fistulas With Occluder Device
Endoscopic closure of tracheoesophageal fistulas with a device used for closure of cardiac septal defects.
- Trial name
- TEFGoreHelex (NCT01153061)
- Testing
- Fistula closure with Gore Helex Septal Occluder, Gore Helex Septal Occluder
- Where
- Brazil
- Volunteers
- 4 people
- Sponsor
- University of Sao Paulo
Atrial Fibrillation, Atrio-Oesophageal Fistula
PrOgnosis Following Esophageal FisTula FormaTion in Pts Undergoing CathetER Ablation for AF Study
Pulmonary vein isolation emerged as an effective and safe strategy to treat atrial fibrillation patients. Atrio-oesophageal fistula (AOF) represents a rare but devastating complication of AF ablation procedure.
- Conditions
- Atrial Fibrillation, Atrio-Oesophageal Fistula, PVI, Catheter Ablation
- Trial name
- POTTER (NCT05273645)
- Where
- Germany
- Volunteers
- 138 people
- Sponsor
- University of Luebeck
Azygos Vein Preservation Versus Disconnection, Tracheo-Esophageal Fistula With Atresia of Esophagus
Azygos Vein Preservation; Its Impact on Early Outcomes After Neonatal EA/TOF Repair
Azygos vein preservation revisited: impact on early outcomes after repair of Esophageal atresia/ Tracheo-Esophageal Fistula in newborns. A randomized controlled study.
- Conditions
- Azygos Vein Preservation Versus Disconnection, Tracheo-Esophageal Fistula With Atresia of Esophagus, Leak, Anastomotic, Stricture Esophagus
- Trial name
- EArAzygousvp (NCT05957562)
- Testing
- EA/TOF primary repair with Azygos vein preservation, EA/TOF primary repair with Azygos vein sacrifice (disconnection)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- dr. Muhammad Abdelhafez Mahmoud, MD
Tracheo Esophageal Fistula
Trichloroacetic Acid for Endoscopic Tracho-esophageal Fistula Repair
Today Endoscopic repair of recurrent Tracheesophageal fistula (TEF) is a safe procedure. Using Trichlosiacetic acid 50% (TCA) for endoscopic aplication of the fistula was reported with a good results ( 4 cases).
- Trial name
- NCT01287312
- Testing
- Endoscopic repair of recurrent TEF by trichloroacetic acid aplications
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Tracheo-Esophageal Fistula Following Tracheostomy
Perceptual Assessment of the Tracheoesophageal Voice
Aim of this study was to validate the Sunderland Tracheoesophageal Perceptual Scale (SToPS) in Italian language by checking the inter- and intra-rater reliability.
- Trial name
- NCT05754671
- Testing
- perceptual assessment of the recorded voice sample, voice recording
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tracheo Esophageal Fistula
Inverse Ratio Ventilation in Neonatal Open Repair of Tracheoesophageal Fistula.
Background and Objectives: Maintaining oxygenation during neonatal open repair of esophageal atresia is difficult. Inverse ratio ventilation can be used during one lung ventilation (OLV) to improve the oxygenation and lung…
- Trial name
- NCT05150600
- Testing
- Inverse Ratio Ventilation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Esophageal Squamous Cell Carcinoma
Quantitative Assessment of Blood Supply in the Gastic Conduit With Fluorescence Angiography for Esophageal Reconstruction
A single-institution, randomize controlled trial is to be held to evaluate the correlation between blood supply in the gastic conduit and the incidence of anastomotic fistula during radical operation for esophageal squamous cell…
- Trial name
- NCT04229524
- Testing
- Fluorescence angiography
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Tracheo-Esophageal Fistula with Atresia of Esophagus
Use of Indocyanine Green During Primary Repair of Oesophageal Atresia and Distal Tracheo-oesophageal Fistula
This study aims to look at babies having a primary or delayed primary oesophageal repair for OA with dTOF to evaluate if using Indocyanine green (ICG) and near infrared fluorescence (NIRF) can decrease the rates of anastomotic…
- Trial name
- iTOF (NCT05735964)
- Testing
- Indocyanine green
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Esophageal Fistula
Esophageal Fistula After Anterior Cervical Decompression and Fusion
This study aims to evaluate the incidence, risk factors, and preventive measures of esophageal fistula following anterior cervical decompression and fusion.
- Trial name
- ACDF (NCT06536738)
- Testing
- esophageal repair
- Volunteers
- 5 people
- Sponsor
- Taizhou Hospital
Atrial Fibrillation, Esophageal Fistula
Retracting the Esophagus During AF Ablation
This Study is designed to determine the outcome and effect of implementation of Esophageal Stylet as a strategy to minimize the risk of esophageal injury during the atrial fibrillation catheter ablation procedure.
- Conditions
- Atrial Fibrillation, Esophageal Fistula, Cardiac Arrhythmia
- Trial name
- EsoSure (NCT02665442)
- Testing
- Esophageal Stylet - EsoSure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northeast Scientific, Inc.