Clinical trials: Esrd
Renal Insufficiency, Chronic
Underlying Causes of Low Vitamin K Status in Hemodialysis Patients
Studies have shown that patients with chronic kidney disease in hemodialysis have a low vitamin K status which is believed to be related to an increased risk of atherosclerosis and increased bleeding tendency.
- Trial name
- NCT03493087
- Testing
- Menakinon 7, Diet rich in vitamin K
- Where
- Denmark
- Volunteers
- 33 people
- Sponsor
- University of Copenhagen
Cardiorenal Syndrome
The Effect in Renal Function on Patients With Type 1 Cardiorenal Syndrome Treated With Two Strategies of Furosemide.
In double-blind clinical trial, determine renal recovery with two different furosemide strategies in patients with type 1 cardiorenal syndrome.
- Trial name
- NCT04393493
- Testing
- Furosemide intravenous solution, Chlortalidone, Spironolactone
- Where
- 2 sites in Mexico
- Volunteers
- 80 people
- Sponsor
- Hospital Civil de Guadalajara
Chronic Kidney Disease
Keto-/Amino Acid Supplemented Low Protein Diet in Patients With Chronic Kidney Disease
Keto-/amino acid supplemented low protein diet can reduce uremic symptoms, improve nutritional status, delay dialysis therapy and enhance health-related quality of life in our patients with stage V CKD in comparison to…
- Trial name
- NCT00364884
- Testing
- ketoaminoacid
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Chronic Kidney Disease, Kidney Transplantation
Pilot Study Evaluating Doxercalciferol Replacement Therapy in Kidney Transplant Recipients
People with kidney transplants often develop bone disease. One reason for bone disease may be overactivity of a gland in the neck called the parathyroid gland.
- Trial name
- NCT00889629
- Testing
- Doxercalciferol, 25-OH Vitamin D3
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Mariana Markell
Chronic Kidney Diseases
Effects of Jaboticaba (Plinia Cauliflora) Supplementation in Chronic Kidney Disease Patients
The increase prevalence of chronic kidney disease (CKD) over the years represent a significant public health problem. The role of inflammation and oxidative stress in the pathophysiology of CKD, as well as progression and…
- Trial name
- NCT06394531
- Testing
- Jaboticaba Peel Extract
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Endometriosis Related Pain, Overactive Bladder
Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function
BAY1817080 is currently under clinical development to treat pain related to unexplained chronic cough or chronic cough not affected by a treatment (refractory and/or unexplained chronic cough, RUCC), or a condition where the…
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04471337
- Testing
- BAY1817080
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Hepatic Impairment; Renal Impairment
Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding
E7080-A001-010 is a multicenter, parallel-group study in participants with mild, moderate, or severe hepatic or renal impairment and age-, gender-, and smoking status-matched healthy participants.
- Trial name
- NCT02998775
- Testing
- Plasma Sampling
- Where
- 3 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
End Stage Kidney Disease
Potassium Containing Salt-Substitute in Hemodialysis-Dependent End Stage Kidney Disease
16 individuals with hemodialysis-dependent end stage kidney disease will receive 16 days of a potassium-containing salt-substitute and 16 days of standard table salt in random order.
- Trial name
- NCT05558267
- Testing
- Standard Table Salt, Salt Substitute
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
End Stage Renal Disease
Safety and Dose Finding Study of Xigris in Hemodialysis Patients
The purpose of the study is to assess the safety of Xigris (Drotrecogin alfa) as an anticoagulant at different dose levels during dialysis treatment in patients with End Stage Renal Disease (ESRD).
- Trial name
- Xigris1003 (NCT01227187)
- Testing
- Drotrecogin alfa activated (Xigris)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- George Washington University
End Stage Renal Disease
Relevance of Flavanols for Cardiovascular Function in End-Stage Renal Disease
In this study, the acute and long-term effects of flavanols on vascular function in patients with ESRD will be investigated.
- Trial name
- ESRD (NCT00835887)
- Testing
- low and high dose flavanoids
- Where
- Germany
- Sponsor
- RWTH Aachen University
Elastography, Chronic Kidney Diseases
Shear Wave Elastography in Differentiating Acute or Chronic Kidney Disease
Chronic kidney disease is a common global public health issue and its prevalence increased year by year. Early diagnosis and intervention can prevent further complications and comorbidities of long-term dialysis, cardiovascular…
- Trial name
- CKD-SWE (NCT04404114)
- Testing
- Shear wave elastography to distinguish AKI from normal kidney, Shear wave elastography to distinguish AKI from CKD, Shear wave elastography to distinguish CKD from normal kidney
- Where
- Taiwan
- Volunteers
- 800 people
- Sponsor
- National Taiwan University Hospital
End-stage Renal Disease, Chronic Kidney Disease
Acupuncture for Pain Management of Hemodialysis Patients
The purpose of this study is to determine the feasibility, effectiveness and safety of acupuncture for pain management in hemodialysis patients.
- Trial name
- NCT01102816
- Testing
- Individualized acupuncture treatment, Routine care
- Where
- 2 sites in South Korea
- Volunteers
- 1 people
- Sponsor
- Korea Institute of Oriental Medicine
Rheumatoid Arthritis, Chronic Kidney Diseases
MySlainte: Testing the Effect of Involving Partners in a CVD Prevention Community Lifestyle Program
MySláinte is a 12-week community-based, multi-disciplinary preventive and lifestyle intervention program to reduce CVD risk factors.
- Conditions
- Rheumatoid Arthritis, Chronic Kidney Diseases, Cardiovascular Risk Factor, Partner, Domestic
- Trial name
- NCT04300465
- Testing
- 10 week MySlainte Program
- Where
- Ireland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Chronic Renal Failure
Safety and Efficacy of Autologous Bone Marrow Stem Cells for Treating Chronic Renal Failure
Chronic renal failure (CRF, or "chronic kidney failure", CKF, or "chronic kidney disease", CKD) is a slowly progressive loss of renal function over a period of months or years and defined as an abnormally low glomerular…
- Trial name
- NCT01152411
- Testing
- Autologous bone marrow stem cells
- Where
- India
- Volunteers
- 5 people
- Sponsor
- International Stemcell Services Limited
Chronic Kidney Failure
Hemodynamics in Chronic Kidney Disease
The goal of this observational study is to learn about the role of thoracic and whole body bioimpedance in the hemodynamic profile of patients with chronic kidney disease.
- Trial name
- HORUZ (NCT06987032)
- Where
- Belgium
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Chronic Kidney Disease
Inspiratory Muscle Training in Chronic Kidney Disease
Chronic kidney disease is a renal injury and progressive and irreversible loss of kidney function and in its most advanced stage is called chronic renal failure.
- Trial name
- NCT03082404
- Testing
- Inspiratory muscle training
- Volunteers
- 25 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Atrial Fibrillation, End Stage Renal Disease
Trial to Evaluate Anticoagulation Therapy in Hemodialysis Patients With Atrial Fibrillation
This is a prospective, randomized, open-label, blinded end-point evaluation trial. The patient population consists of patients on hemodialysis who have atrial fibrillation (AF) and end-stage renal disease (ESRD) .
- Trial name
- RENAL-AF (NCT02942407)
- Testing
- apixaban, warfarin
- Where
- 58 sites in United States
- Volunteers
- 154 people
- Sponsor
- Christopher Granger, MD
Chronic Kidney Diseases, Acute Kidney Injury
Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression
Chronic kidney disease CKD is estimated to affect nearly over 800 million people globally today (with roughly 125,000 people ending up annually on dialysis in the United States alone.
- Conditions
- Chronic Kidney Diseases, Acute Kidney Injury, Kidney Failure
- Trial name
- NAD agent (NCT06866236)
- Testing
- QRX-3
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Ebima Clifford Okundaye
Heart Failure, Acute Kidney Injury
Furosemide Stress Test for the Prediction of Acute Kidney Injury Severity in Acute Heart Failure Patients
This study is aim to study the changes of serum creatinine levels at 72 hours after admission in patients with acute heart failure who has diuretic resistance compared to those who do not have diuretic resistance from furosemide…
- Trial name
- NCT04464811
- Testing
- Furosemide stress test
- Where
- Thailand
- Volunteers
- 257 people
- Sponsor
- Chiang Mai University
Healthy Volunteers, Renal Failure
Pharmacokinetics in End Stage Renal Disease Patients
The study is a multicentre, open label, phase I, two arms study to compare pharmacokinetic of firibastat after a single oral dose of firibastat 500 mg in fourteen healthy male volunteers and in fourteen End Stage Renal Disease…
- Trial name
- NCT04792333
- Testing
- firibastat
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Quantum Genomics SA
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