Clinical trials: Esrd
Chronic Kidney Disease Due to Hypertension, Chronic Kidney Disease Due to Type 2 Diabetes Mellitus
Fecal Microbiota Transplantation as a Therapeutic Strategy in the Progression of Chronic Kidney Disease
What the investigators want to achieve with the protocol is to identify the impact of intestinal microbiota transplantation on the progression of chronic kidney disease.
- Trial name
- NCT04361097
- Testing
- Faecal microbiota transplant
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Type 2 Diabetes, Chronic Kidney Disease (CKD) Stages G2 to G3b
A Study to Learn More About How Well Finerenone Works in Real-world in People With Type 2 Diabetes and Chronic Kidney Disease in Primary Care (IMSS= Instituto Mexicano Del Seguro Social)
The main purpose of this study is to learn how treatment with finerenone affects the urinary albumin-to-creatinine ratio (uACR), a marker of kidney health, over time in adults with type 2 diabetes and chronic kidney disease who…
- Trial name
- FINE-IMSS-MX (NCT07841015)
- Testing
- Finerenone
- Where
- Mexico
- Volunteers
- 800 people
- Sponsor
- Bayer
Anemia
A Phase 2a Study To Evaluate The Pharmacokinetics, Safety, Efficacy, Tolerability, And Pharmacodynamics of Sotatercept (ACE-011) for the Correction of Anemia in Subjects With End-stage Renal Disease on Hemodialysis.
This is the first study in hemodialysis subjects with anemia to evaluate the pharmacokinetics, safety, efficacy, tolerability, and pharmacodynamics of sotatercept (ACE-011)
- Trial name
- NCT01146574
- Testing
- Sotatercept
- Where
- 24 sites in United States
- Volunteers
- 50 people
- Sponsor
- Celgene
Critical Illness, Acute Kidney Injury
Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure
The use of extracorporeal blood purification therapies (EBPT) is becoming increasingly widespread worldwide in everyday clinical practice, particularly in the critical care setting.
- Conditions
- Critical Illness, Acute Kidney Injury, Sepsis, Systemic Inflammatory Response Syndrome
- Trial name
- NCT04033224
- Testing
- Commercial membrane for Extracorporeal Blood Purification Therapy (EBPT)
- Where
- 15 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Careggi Hospital
Acute Kidney Injury, The Changes of Plasma Creatinine
Short-Term Alpha Lipoic Acid Therapy for Prevention of Contrast-induced Acute Kidney Injury and Endothelial Dysfunction in Type 2 Diabetes
Contrast-induced acute kidney injury (CIAKI) is a major complication with adverse outcomes after contrast media injection. Although the risk of developing CIAKI is low in patients with normal renal function, it is dramatically…
- Conditions
- Acute Kidney Injury, The Changes of Plasma Creatinine, The Changes of Plasma Free Radicals, The Changes of Endothelium-dependent Arterial Dilation
- Trial name
- NCT01978405
- Testing
- Alpha lipoic acid
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xiang Guang-da
Hyperkalemia
Patiromer for the Management of Hyperkalemia in Subjects Receiving RAASi Medications for the Treatment of Heart Failure (DIAMOND)
The purpose of this study is to assess the effects of patiromer compared with placebo on serum K+ in HF patients.
- Trial name
- DIAMOND (NCT03888066)
- Testing
- Patiromer
- Where
- 415 sites in United States, Argentina and 19 more
- Volunteers
- 1,195 people
- Sponsor
- Vifor Pharma, Inc.
Chronic Kidney Disease
Efficacy Trial of N-Acetylcysteine and Sodium Bicarbonate for the Prevention of Contrast-Induced Acute Kidney Injury
Contrast-Induced Acute Kidney Injury(CIAKI) was defined as an absolute increase in serum creatinine of more than or equal to 0.3mg/dl (≥ 26.4 μmol/l), a percentage increase in serum creatinine of more than or equal to 50%…
- Trial name
- PREKIT (NCT01210456)
- Testing
- Physiological Saline, N-Acetylcysteine and Sodium Bicarbonate
- Where
- Japan
- Volunteers
- 458 people
- Sponsor
- Tokushukai Medical Group
Renal Insufficiency, Pharmacokinetics
A Single Dose Study Investigating the Elimination as Well as the Tolerability of PD 0332334 in Healthy Subjects as Compared to Patients With Impaired Kidney Function.
1. To investigate the effect of kidney function on the elimination of a single dose of PD 0332334 from the body. 2. To investigate the safety and tolerability of a single dose of PD 0332334 in patients with impaired kidney…
- Trial name
- NCT00721422
- Testing
- PD 0332334
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Arteriovenous Graft
LineMatrix® Biological Vascular Graft for the Creation of Arteriovenous Graft
The study is planned to be conducted at multiple centers, with an intended enrollment of 326 subjects. Protocol-eligible subjects will be randomized in a 1:1 ratio to either the investigational group or the control group.
- Trial name
- NCT07773051
- Testing
- LineMatrix® Biological Vascular Graft, GORE-INTERING®
- Where
- 12 sites in China
- Volunteers
- 326 people
- Sponsor
- Longhua Hospital
Diabetes Mellitus, Type 2
A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.
This randomized, double-blind, active-controlled study evaluates the efficacy and safety of a weekly dose of albiglutide as compared with sitagliptin.
- Trial name
- NCT01098539
- Testing
- albiglutide, sitagliptin
- Where
- 218 sites in United States, Australia and 13 more
- Volunteers
- 507 people
- Sponsor
- GlaxoSmithKline
Continuous Renal Replacement Therapy (CRRT), End Stage Kidney Disease (ESRD)
Prospective Analysis of Arteriovenous Access (AVA) Use in Continuous Renal Replacement Therapy: A Feasibility Project
This study will test whether patients who already have a permanent dialysis access (an arteriovenous fistula or graft) can safely use that access for continuous dialysis (CRRT) while they are critically ill in the intensive care…
- Trial name
- CRRT (NCT07447128)
- Testing
- Cannulation of permanent dialysis access, for the purpose of delivering continuous renal replacement therapy.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- East Carolina University
Renal Insufficiency
Colour Coded Duplex Ultrasound of Native Arterio-venous Fistula for Haemodialysis With Venous Pressure Measurement Using Controlled Compression Ultrasound as a Predictor for Shunt Maturation in the Early Postoperative Phase
Prospective observational ultrasound study of native arterio-venous fistula for haemodialysis with venous pressure measurement using controlled compression ultrasound.
- Trial name
- NCT01001000
- Testing
- Ultrasound (Pressure measurement)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Chronic Kidney Disease, Hypertension
Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy
Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention that identifies hospitalized African Americans with advanced chronic kidney disease (CKD) and provides them…
- Trial name
- iPREP-RRT (NCT06397456)
- Testing
- In-Person Patient Education, Commitment to Change, Blood pressure monitoring
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Chicago
Arterial Hypertension, Chronic Kidney Disease
PRospectIve ObseRvatIonal mulTicenter Study of Patients With Arterial hYpertension and CKD in the Population of Russia
This study is a multi-centre, non-interventional, observational, prospective study with retrospective analysis. The main purpose of the study is to describe the rate of CKD diagnosis in patients with AH and CKD markers.
- Trial name
- PRIORITY-CKD (NCT06372431)
- Where
- 30 sites in Russia
- Volunteers
- 9,914 people
- Sponsor
- AstraZeneca
Influenza, Renal Failure
Pharmacokinetic Assessment of Peramivir in Hospitalized Adults Undergoing Continuous Renal Replacement Therapy
Pharmacokinetics for peramivir have not been well characterized in patients undergoing continuous renal replacement therapy CRRT - either Continuous veno-venous hemofiltration (CVVH) +/- dialysis (CVVHD).
- Trial name
- NCT01146353
- Where
- United States
- Sponsor
- Midwestern University
Hypotension, Acute Kidney Injury
A Clinical Decision Support Trial to Reduce Intraoperative Hypotension
The purpose of this study is to provide messages to providers if their patient is at high risk of developing intraoperative hypotension based on past medical history and co-morbidities preoperatively and minutes of hypotension…
- Trial name
- NCT04062994
- Testing
- Nudge to reduce intraoperative hypotension
- Where
- 4 sites in United States
- Volunteers
- 30,000 people
- Sponsor
- University of California, Los Angeles
Chronic Kidney Disease(CKD), Renal Transplantation
Knowledge of Cardiovascular Risk Factors in Chronic Kidney Disease Patients
The aim of this study is to assess knowledge of cardiovascular risk factors, physical activity levels, health literacy and perceptions of benefits and barriers to exercise in patients with chronic kidney disease and compare them…
- Trial name
- NCT06674031
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Kidney Transplantation in Highly Sensitized Patients
Efficacy and Safety in Imlifidase Desensitized Kidney Tx Patients, Including Two Non-Comparative Reference Cohorts
An open-label post authorization efficacy and safety study evaluating graft failure-free survival at 1-year in highly sensitized end-stage renal disease (ESRD) patients with positive crossmatch (XM) against a deceased donor prior…
- Trial name
- PAES (NCT05369975)
- Testing
- Imlifidase, Normal Transplantation Routine
- Where
- 22 sites in Austria, Belgium and 9 more
- Volunteers
- 113 people
- Sponsor
- Hansa Biopharma AB
End Stage Renal Disease, Kidney Failure
Virtual Ward for Home Dialysis
Home based renal replacement therapy (RRT), including peritoneal dialysis (PD) and home hemodialysis(HHD), offers enhanced quality of life and clinical advantages compared to conventional in-center hemodialysis.
- Conditions
- End Stage Renal Disease, Kidney Failure, Home Dialysis
- Trial name
- Virtual Ward (NCT01912001)
- Testing
- Telephone follow-up, Sympton Assessment
- Where
- 7 sites in Canada
- Volunteers
- 215 people
- Sponsor
- Christopher Chan
Chronic Renal Failure
Open Label Trial to Establish the Equivalence Between ANDY-Disc® and Ultrabag® in Patients on CAPD.
Apart from haemodialysis, continuous ambulatory peritoneal dialysis (CAPD) is another effective therapy for end stage renal disease (ESRD).
- Trial name
- NCT00255619
- Testing
- Baxter's UltraBag® and FMC Andy·Disc®
- Where
- 6 sites in Malaysia
- Volunteers
- 264 people
- Sponsor
- Ministry of Health, Malaysia
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