Clinical trials: Esrd
Anemia, End Stage Renal Disease
16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Participants With End Stage Renal Disease (ESRD) Requiring Chronic Hemodialysis
The purpose of this study is to evaluate the hemoglobin response (efficacy), safety, and tolerability of orally administered AKB-6548 in participants with end stage renal disease undergoing chronic hemodialysis.
- Trial name
- NCT02260193
- Testing
- AKB-6548
- Where
- 16 sites in United States
- Volunteers
- 94 people
- Sponsor
- Akebia Therapeutics
Chronic Kidney Diseases, Hemodialysis
Effects of Supplementation With Tocotrienol on Chronic Kidney Disease Patients
The objective of this study is to evaluate the supplementation with tocotrienol, a vitamin E compound on inflammation, oxidative stress, and microbiota on Chronic Kidney Disease patients.
- Conditions
- Chronic Kidney Diseases, Hemodialysis, Microbiota, Oxidative Stress
- Trial name
- NCT04900532
- Testing
- Tocotrienol rich fraction
- Where
- Brazil
- Volunteers
- 61 people
- Sponsor
- Universidade Federal Fluminense
Chronic Renal Insufficiency, Serum Creatinine Concentration
MESNA for Prevention of Acute Deterioration of Renal Function Following Contrast Agent Application
The purpose of this study is to determine wether Mesna could prevent contrast-induced nephropathy
- Conditions
- Chronic Renal Insufficiency, Serum Creatinine Concentration, Contrast Media Exposition
- Trial name
- NCT00223548
- Testing
- sodium 2-mercaptoethane sulfonate
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- University of Ulm
Acute Kidney Injury
Efficacy of RIPC to Reduce AKI for Patients Undergoing PCI
The purpose of the present study is to determine if remote ischemic preconditioning reduces incidence of acute kidney injury in patients with reduced kidney function undergoing Percutaneous Coronary Intervention.
- Trial name
- EUROCRIPS (NCT02195726)
- Testing
- Remote ischemic preconditioning
- Where
- 7 sites in France, Italy and 1 more
- Volunteers
- 1,110 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Chronic Renal Failure, Diabete Type 2
Symbiotics and Systemic Inflammation in Chronic Kidney Disease
Main objective: To assess the effectiveness of treatment with symbiotics on the chronic systemic inflammation observed in chronic renal failure 4 months after the start of treatment.
- Conditions
- Chronic Renal Failure, Diabete Type 2, Systemic Inflammation
- Trial name
- SISMIC (NCT04769687)
- Testing
- probiotic Vivomixx®, prebiotic Orafti®Synergy1
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Photochemotherapy, Renal Insufficiency, Chronic
Antimicrobial Photodynamic Therapy in the Nasal Decolonization of Maintenance Hemodialysis Patients
The objective of this study will be to evaluate the effect of Antimicrobial Photodynamic Therapy (aPDT) in the Nasal Decolonization of Dialytic Chronic Renal Patients, Staphylococcus Aureus (S.aureus) Carriers This is a 3-months…
- Trial name
- NCT04047914
- Testing
- Antimicrobial Photodynamic therapy, Mupirocin ointment
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Chronic Kidney Diseases, Hyperkalemia
Use of Patiromer to Transition Chronic Kidney Disease Patients With Hyperkalemia to a Plant-rich Diet.
The purpose of this proof-of-concept controlled-feeding study is to determine whether patiromer (Veltassa®, Relypsa, Inc., Redwood City, CA) can be used to maintain normal serum potassium concentrations in chronic kidney disease…
- Trial name
- NCT03183778
- Testing
- Patiromer, Research Diet Menu
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- NYU Langone Health
Acute Kidney Injury
Acute Kidney Attack in Severe Traumatized Patients
Acute Kidney Injury (AKI) is a common complication of severe traumatized patients. The diagnosis is often delayed. The Nephrocheck® test allows an earlier assessment of renal stress.
- Trial name
- NEPHROTRAUMA (NCT03877978)
- Testing
- Nephrocheck test
- Where
- France
- Volunteers
- 196 people
- Sponsor
- Hospices Civils de Lyon
Acute Kidney Injury, Fluid Overload
Prospective, Multi-center, Single-arm, Observational Study. US FDA 522 Pediatric Post Market Surveillance Study.
The post market surveillance study will employ a prospective, multi-center, single-arm, observational design to capture data on children who undergo CRRT using the Carpediem™ system.
- Trial name
- NCT04608149
- Testing
- Carpediem System
- Where
- 6 sites in United States
- Volunteers
- 36 people
- Sponsor
- Mozarc Medical US LLC
Chronic Kidney Disease
EPO Deep Tank in Dialysis Subjects
Subject incidence of adverse events
- Trial name
- NCT00156949
- Testing
- Epoetin alfa DT
- Volunteers
- 580 people
- Sponsor
- Amgen
Hyperphosphatemia, Kidney Failure
A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis
This is up to a 58 week study comparing ferric citrate to active control for 52 weeks in ESRD dialysis patients, and subsequently comparing ferric citrate to placebo for 4 weeks.
- Trial name
- NCT01191255
- Where
- 56 sites in United States, Israel and 1 more
- Volunteers
- 441 people
- Sponsor
- Keryx Biopharmaceuticals
Nephrolithiasis
Outcomes and Inter-Stage Interval in Staged Bilateral PCNL
This prospective, single-center observational study evaluated patients undergoing staged bilateral standard percutaneous nephrolithotomy (PCNL) for bilateral renal stones.
- Trial name
- NCT07854743
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Ankara Training and Research Hospital
Atrial Fibrillation, Rivaroxaban
Rivaroxaban in Elderly NVAF Patients With or Without Renal Impairment
Study Type and Design Prospective, Observational Study Rivaroxaban in Elderly AF patients with or without renal impairment in Korea This study will investigate effectiveness and safety in elderly patients, the result from…
- Conditions
- Atrial Fibrillation, Rivaroxaban, Elderly, Renal Insufficiency
- Trial name
- XAIENT (NCT04096547)
- Testing
- Rivaroxaban
- Where
- South Korea
- Volunteers
- 1,200 people
- Sponsor
- Samsung Medical Center
Acute Kidney Injury, Extracorporeal Circulation; Complications
Tissue Inhibitor of Metalloproteinases 2 Level in Patients Undergoing Cardiac Surgery
Acute kidney injury (AKI) is one of the most frequent major complications in patients undergoing cardiac surgery. CSA-AKI is independently related to increased perioperative mortality, increased hospital and ICU length of stay as…
- Conditions
- Acute Kidney Injury, Extracorporeal Circulation; Complications, Surgery
- Trial name
- NCT06871826
- Testing
- TIMP2 level
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wuhan University
Renal Impairment
A Study to Test How Kidney Problems Influence the Blood Concentrations of Efgartigimod
A study to test how kidney problems influence the blood concentrations of efgartigimod
- Trial name
- NCT05927415
- Testing
- Efgartigimod IV
- Where
- 2 sites in Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- argenx
Renal Impairment
Phase 1 Study of PK and Safety of SPR206 in Subjects With Various Degrees Of Renal Function
Evaluation of the pharmacokinetics (PK) of SPR206 in subjects with normal renal function, subjects with various degrees of renal insufficiency, and subjects with end-stage renal disease (ESRD) receiving hemodialysis (HD) therapy.
- Trial name
- NCT04865393
- Testing
- SPR206
- Where
- 2 sites in New Zealand
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Spero Therapeutics
Septic Shock, Acute Kidney Injury
Norepinephrine / Vasopressin Combination for Resuscitation in Septic Shock
Although norepinephrine is commonly used and is the recommended agent for the treatment of hypotension in volume-resuscitated hyperdynamic septic shock, Low doses of vasopressin may be added to norepinephrine to maintain arterial…
- Trial name
- NCT04302584
- Testing
- norepinephrine / Vasopressin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Kidney Transplantation, ESRD
Donor Dopamine and Initial Graft Function
Donor pre-treatment with dopamine reduces injury to the kidney graft with consequences on the clinical performance immediately after transplantation: Donor dopamine reduces the requirement of dialysis post transplant, and results…
- Trial name
- NCT00115115
- Testing
- Dopamine infusion to brain dead organ donors
- Where
- Germany
- Volunteers
- 487 people
- Sponsor
- Universitätsmedizin Mannheim
Dyslipidemias, Children, Only
The Effect of Childhood Dyslipidemia on Endothelial and Renal Function
The aim of the study is to assess if abnormal lipid levels in childhood could cause early damage of the inner layer of the vessels, the endothelium.
- Conditions
- Dyslipidemias, Children, Only, Endothelial Dysfunction, Renal Dysfunction
- Trial name
- NCT03856476
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Renal Insufficiency
Effects of Creatine Supplementation on Renal Function
Creatine (CR) supplementation is commonly used by athletes. However, its effects on renal function remain controversial. The aim of this study was to evaluate the effects of creatine supplementation on renal function and…
- Trial name
- NCT00465140
- Testing
- creatine supplementation, aerobic exercise training
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
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