Clinical trials: Esrd
Acute Kidney Injury
Lithium Clearance in Patients With High Risk of Acute Kidney Injury
Renal lithium clearance is hypothesized to be a useful indicator of renal tubular function. In this study lithium clearance will be monitored in patients with sepsis associated acute kidney injury and in healthy controls.
- Trial name
- NCT05648435
- Testing
- Lithium measures
- Where
- Norway
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Stage 5 Chronic Kidney Disease, Hemodialysis
Comparison of Outcomes Between Hemodialysis and Peritoneal Dialysis Patients in a Multi-Ethnic Asian Population
End-stage renal disease (ESRD) presents a heavy burden on a patient's psychological and social life, as well as overall quality of life (QoL).
- Conditions
- Stage 5 Chronic Kidney Disease, Hemodialysis, Peritoneal Dialysis
- Trial name
- NCT01587443
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University of Singapore
End Stage Renal Disease on Dialysis
Motivational Strategies To Empower African Americans To Improve Dialysis Adherence
This study addresses the need to rigorously advance the science and understanding of the development, feasibility, acceptability and adoption of novel culturally-sensitive motivational strategies to improve dialysis treatment…
- Trial name
- MoVE (NCT05003115)
- Testing
- Motivational interviewing
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Kidney Disease
Effects of Low Protein Diet Supplemented Keto-/Amino Acid in Preventing the Progression of Chronic Kidney Disease (CKD)- ELPD Study
The purpose of this study is to determine whether low protein diet and very low protein diet supplemented keto-/amino acid is effective in preventing the progression of chronic kidney disease (CKD , stage 3b and 4).
- Trial name
- ELPD-CKD (NCT01418508)
- Testing
- low protein diet plus α-keto acid, very low protein diet plus α-keto acid
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
End Stage Kidney Disease, Kidney Transplantion
The Response of the Immune System of Patients With End Stage Kidney Disease on Dialysis and Kidney Transplant Recipients Vaccinated for COVID-19
Observational study of patients with End Stage Kidney Disease on dialysis and Kidney Transplant Recipients, before and after vaccination for SARS-COV 2, after written consent, with the aim of laboratory efficacy of the vaccine…
- Conditions
- End Stage Kidney Disease, Kidney Transplantion, Covid19, Vaccination
- Trial name
- NCT04932876
- Testing
- SARS - COV 2 VACCINE
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Ioannina
Peritoneal Dialysis, Hemodialysis, Home
Experiences and Health-related Quality of Life of Informal Caregivers of Dialysis Patients
The goal of this prospective, observational, multicentre cohort study is to assess the trajectory of the experiences (both positive and negative) and health-related quality of life (HRQOL) of informal caregivers of patients who…
- Conditions
- Peritoneal Dialysis, Hemodialysis, Home, Hemodialysis, Quality of Life
- Trial name
- NCT05646615
- Where
- 33 sites in Belgium, Netherlands
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- B.C. van Jaarsveld
Kidney Failure, Chronic
Effects of Probiotics on the Patients With End Stage Renal Disease (ESRD)
The purpose of this study is to investigate the effects of oral administration of probiotics on the metabolism of uremic toxins, in the patients with End Stage Renal Disease (ESRD).
- Trial name
- NCT03010735
- Testing
- probiotics
- Where
- 3 sites in China
- Volunteers
- 150 people
- Sponsor
- China Agricultural University
Acute Kidney Injury, Critical Illness
Preventing Acute Kidney Injury and Improving Outcome in Critically Ill Patients Utilising Risk Prediction Score
An interventional controlled trial to test the feasibility of applying risk score based prevention for critically ill patient at high risk to develop acute kidney injury (AKI)
- Trial name
- PRAIOC-RISKS (NCT03178435)
- Testing
- Measures to prevent AKI among critically ill patients
- Where
- Egypt
- Volunteers
- 198 people
- Sponsor
- Kasr El Aini Hospital
Contrast-associated Acute Kidney Injury
An Observational Study of Percutaneous Glomerular Filtration Rate (TGFR) in the Early Warning of Contrast-induced Acute Kidney Injury During the Peri-examination Period of Emergency Enhanced CT
This is a single-center, prospective observational study. We aim to evaluate the performance of transdermal glomerular filtration rate (TGFR) compared with baseline estimated glomerular filtration rate (eGFR) for early prediction…
- Trial name
- NCT07850947
- Testing
- Transdermal glomerular filtration rate (TGFR) monitoring
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Kidney Disease, Chronic, Kidney Failure Chronic
Physical Exercise and Biomolecular Analysis to Reduce Uremic Toxins in Chronic Kidney Disease: An Exploratory Study
The accumulation of uremic toxins is detrimental to physiological systems and induces premature biological aging. Renal function assessment methods, such as predictive formulas, may be influenced by ancestry in Brazilians, given…
- Trial name
- DRC_LExS (NCT06910475)
- Testing
- Resistance training, Endurance training, Concurrent training
- Where
- Brazil
- Volunteers
- 1,600 people
- Sponsor
- Catholic University of Brasília
Renal Insufficiency, Diabetes
Pharmacodynamic Comparison of Truncal Blocks in Patients With or Without Metabolic Disease (Kidney Failure, Diabetes)
The primary objective is to demonstrate a longer period of neurologic recovery from a sensory block assessed in each test group versus the group without metabolic disease.
- Trial name
- NCT01323075
- Testing
- Truncal block
- Where
- 3 sites in France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
End Stage Renal Disease (ESRD)
Delivery of Soluble Ferric Pyrophosphate (SFP) Via the Dialysate to Maintain Iron Balance in Hemodialysis Patients
In maintenance hemodialysis patients, regular administration of parenteral iron by addition of soluble ferric pyrophosphate (SFP) to the dialysate, when compared to conventional dialysate, is effective in preventing the…
- Trial name
- NCT00604565
- Testing
- soluble ferric pyrophosphate (SFP)
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Charles Drew University of Medicine and Science
Chronic Kidney Disease, Overactive Bladder
Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly
This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each…
- Conditions
- Chronic Kidney Disease, Overactive Bladder, Benign Prostatic Hyperplasia, Female Pelvic Floor Dysfunction
- Trial name
- UFMR-BE (NCT07357714)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
End Stage Kidney Disease
Sarcopenia and Physical Performance in Hemodialysis Patients
Many systems such as the cardiovascular, pulmonary, musculoskeletal, hematological, immunological, gastrointestinal, central nervous system are affected due to decreased kidney function.
- Trial name
- NCT04669184
- Volunteers
- 26 people
- Sponsor
- Hacettepe University
Chronic Kidney Disease
Dialysis Clinical Outcomes Revisited (DCOR) Trial
This is a randomized, open-label, parallel-design study to be conducted at 75 centers within the United States. The study will be described to hemodialysis patients.
- Trial name
- NCT00324571
- Testing
- Sevelamer hydrochloride, Calcium-based phosphate binder
- Where
- 73 sites in United States, Puerto Rico
- Volunteers
- 2,000 people
- Sponsor
- Genzyme, a Sanofi Company
Chronic Kidney Disease Stage 3 and 4, Peripheral Artery Disease (PAD)
Exercise Activity to Improve Mobility in Patients With CKD and PAD
People affected by chronic kidney disease and concomitant diagnosed peripheral artery disease at intermediate stages, without contraindications to exercise therapy will be invited to participate in the study.
- Trial name
- EXACT-CKDPAD (NCT06621264)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Control (Standard treatment)
- Where
- 3 sites in Italy
- Volunteers
- 124 people
- Sponsor
- University Hospital of Ferrara
Von-Hippel Lindau, Kidney Disease, Chronic
Contrast-enhanced Ultrasound as a Screening Tool for Kidney Cancer in Patients With Von-Hippel Lindau
The purpose of this study is to determine if contrast-enhanced ultrasound can detect abnormal features of kidney lesions in patients with Von-Hippel Lindau with the same accuracy as conventional ultrasound and contrast-enhanced…
- Trial name
- CEUS-VHL (NCT03907657)
- Testing
- Perflutren lipid microsphere, Sulfur hexafluoride lipid microspheres
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
End Stage Kidney Disease
Evaluation of a Website on Living Kidney Donation for Hispanics
The purpose of this study is to increase understanding about living kidney donation (LKD) among Hispanic/Latino patients and public by increasing knowledge and positive attitudes about LKD.
- Trial name
- NCT01859871
- Testing
- Website Intervention
- Where
- 2 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obstructive Sleep Apnea, Overhydration
Effect of Intermittent Hemodialysis on Sleep Apnea Syndrome in End Stage Renal Disease Patients
The purpose of this study is to investigate the effect of decreasing fluid overload by hemodialysis on the severity of obstructive sleep apnea, in patients with end stage chronic kidney disease on intermittent hemodialysis.
- Conditions
- Obstructive Sleep Apnea, Overhydration, End Stage Renal Disease
- Trial name
- SASinHD (NCT01860209)
- Testing
- Hemodialysis
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Hyperphosphatemia, End-stage Renal Disease
A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD)
This study is to evaluates the safety and tolerability of Zerenex™ (ferric citrate) as a treatment for hyperphosphatemia in patients with End-Stage Renal Disease.
- Trial name
- NCT00648167
- Testing
- ferric citrate
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Keryx Biopharmaceuticals
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