Clinical trials: Esrd
Chronic Kidney Disease 5D
Bio-ADM as a Biomarker of Refilling in Chronic Hemodialysis Patient
Aim of this study is to evaluate in a population of chronic kidney disease patients on dialysis (Stage 5D) the predictive value of bio-adrenomedullin (bio-ADM) level on vascular refilling rate.
- Trial name
- REFILBIOADM (NCT05339009)
- Testing
- BioADM determination in plasma
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Chronic Renal Failure Related Anemia
Efficacy and Safety Study of GerEPO
The purpose of the study is to establish the equivalence of GerEpo with the standard treatment Eprex® for a treatment period of 12 weeks in patients on Hemodialysis with respect to hemoglobin response and to establish the…
- Trial name
- NCT00229099
- Testing
- GerEPO
- Where
- 32 sites in Malaysia
- Volunteers
- 270 people
- Sponsor
- Ministry of Health, Malaysia
Chronic Kidney Failure
Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients
Patients with kidney failure rely on dialysis for sodium and fluid removal. The importance of a sodium and fluid balance in patients with kidney disease is very important.
- Trial name
- NCT05185999
- Testing
- Icodextrin/Dextrose
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Kidney Disease
Low Phosphate Diets in Patients With Early Stages of Chronic Kidney Disease
The purpose of this study is to learn more about how the kidneys control the blood levels of phosphorus in patients with early chronic kidney disease.
- Trial name
- NCT00438932
- Testing
- Lanthanum Carbonate, Low Phosphorus Diet, Unrestricted Phosphorus Diet
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Massachusetts General Hospital
Chronic Kidney Disease, End Stage Kidney Disease
Reduction of Mortality Prior to and During the First 90 Days of Dialysis Through a Renal Rehabilitation Program
The mortality rate of treated patients with end stage renal disease(ESRD)is 22 deaths patient-years at risk in 2006. Incident patients with ESRD are most vulnerable within the first 90 days of dialysis, with an annualized…
- Conditions
- Chronic Kidney Disease, End Stage Kidney Disease, Cardiovascular Disease
- Trial name
- NCT00792454
- Testing
- exercise training
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- MaineHealth
Renal Failure
Optimizing Cardiovascular Health and Physical Function in Hemodialysis Patients Through Volume Control and Exercise
This is a 12 month randomized clinical trial in which patients with renal failure undergoing maintenance hemodialysis (MHD) therapy will be placed on a volume reduction protocol that includes a novel low sodium dietary education…
- Trial name
- VCE (NCT02627066)
- Testing
- Volume Control, Volume Control + Exercise
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Illinois at Urbana-Champaign
AKI, AKI - Acute Kidney Injury
Outpatient Recovery From Acute Kidney Injury Requiring Dialysis - 2
Providing additional information to patients with acute kidney injury who continue dialysis after hospital discharge and to the accepting kidney doctor (nephrologist) who manages their dialysis may be feasible and beneficial.
- Conditions
- AKI, AKI - Acute Kidney Injury, Dialysis Patients
- Trial name
- ORKID-2 (NCT07106151)
- Testing
- Transmission of additional AKI-D recovery information, No additional AKI-D recovery information
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Kidney Insufficiency, Diabetes Mellitus
Plant Versus Animal Dietary Protein and the Effect on Proteinuria
The purpose of this study is to investigate if a diet high in plant protein improves kidney function in patients with kidney insufficiency and diabetes and/or hypertension and/or glomerulonephritis.
- Conditions
- Kidney Insufficiency, Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- NYPRO (NCT04058951)
- Testing
- High Animal Protein Diet (HAPD), High Plant Protein Diet (HPPD)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Jens Rikardt Andersen
BRAF Gene Mutation, Hepatic Complication
Dabrafenib in Treating Patients With Solid Tumors and Kidney or Liver Dysfunction
This phase I trial studies the side effects and best dose of dabrafenib in treating patients with solid tumors and kidney or liver dysfunction.
- Conditions
- BRAF Gene Mutation, Hepatic Complication, Renal Failure, Solid Neoplasm
- Trial name
- NCT01907802
- Testing
- Dabrafenib, Laboratory Biomarker Analysis, Pharmacogenomic Study
- Where
- 18 sites in United States, Canada
- Volunteers
- 8 people
- Sponsor
- National Cancer Institute (NCI)
Liver Transplantation, Chronic Renal Insufficiency
Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver Transplantation
A prospective, non-randomized two stage monocentric phase II clinical trial to evaluate a de-novo calcineurin-inhibitor (CNI)-free immunosuppressive regimen based on induction therapy with anti-CD25 monoclonal anti-body…
- Trial name
- CILT (NCT00890253)
- Testing
- Basiliximab (Simulect), Myfortic, everolimus
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- Armin Goralczyk
Acute Kidney Injury
Effect of Cholesterol Level on Postoperative Acute Kidney Injury of Non-cardiac Surgeries
Preoperative serum cholesterol level may influence occurrence of postoperative acute kidney injury of cardiac surgeries. However, the effect of Preoperative serum cholesterol level for non cardiac surgery remains unknown.
- Trial name
- NCT03954353
- Where
- China
- Volunteers
- 78,888 people
- Sponsor
- Peking University First Hospital
Renal Insufficiency, Chronic, Potassium Depletion
Potassium Supplementation in CKD
The current high-sodium, low-potassium diet contributes to the high prevalence of high blood pressure (hypertension). Indeed, the anti-hypertensive effects of potassium supplementation are well-established.
- Conditions
- Renal Insufficiency, Chronic, Potassium Depletion, Hypertension, Hyperkalemia
- Trial name
- K+ in CKD (NCT03253172)
- Testing
- Potassium Chloride, Potassium Citrate
- Where
- 4 sites in Netherlands
- Volunteers
- 532 people
- Sponsor
- Erasmus Medical Center
Renal Failure, Hemodialysis
GORE VIABAHN Endoprosthesis Versus Percutaneous Transluminal Angioplasty (PTA) to Revise AV Grafts in Hemodialysis
The objective of the study is to establish efficacy and safety of the GORE VIABAHN® Endoprosthesis with PROPATEN Bioactive Surface when used to revise arteriovenous (AV) prosthetic grafts at the venous anastomosis in the…
- Trial name
- REVISE (NCT00737672)
- Testing
- GORE VIABAHN Endoprosthesis with PROPATEN Bioactive Surface, Percutaneous Transluminal Angioplasty
- Where
- 31 sites in United States
- Volunteers
- 293 people
- Sponsor
- W.L.Gore & Associates
Anemia Associated With Chronic Kidney Disease
Investigating the Efficacy, Safety and PK of Roxadustat (FG-4592) for Treatment of Anemia in Pediatric Patients With CKD
This open-labeled, multicenter study is designed to evaluate the efficacy, safety and PK/PD of roxadustat in ESA-naïve and ESA-treated pediatric patients with CKD Stages 3, 4, and 5, as well as end-stage renal disease (ESRD) who…
- Trial name
- NCT04621331
- Testing
- Roxadustat
- Where
- 4 sites in United States
- Sponsor
- Kyntra Bio
Acute Kidney Injury, Uremia
Timing of Renal Replacement Therapy in the Critically Ill Patients
Background: Severe acute kidney injury (AKI) among critically ill patients is sometimes treated with renal replacement therapy (RRT), and in Sweden continuous RRT (CRRT) is the dominant modality used in this population.
- Conditions
- Acute Kidney Injury, Uremia, Fluid Overload, Dialysis; Complications
- Trial name
- TORRT (NCT03629977)
- Testing
- CRRT
- Where
- Sweden
- Volunteers
- 50,000 people
- Sponsor
- Karolinska University Hospital
Kidney Failure, Acute
Study of Heat Shock Proteins as Prognostic Factor of Acute Renal Failure in Children (HSP-Study)
The purpose of the investigators' study is to determine whether the production of heat shock proteins has an effect on the development and the outcome of acute renal failure in children.
- Trial name
- HSP (NCT00230412)
- Where
- 6 sites in Germany
- Volunteers
- 120 people
- Sponsor
- University of Munich Children's Clinic
End-stage Renal Disease, Hemodialysis
Does Moderate Physical Activity in Hemodialysis Patients Reduce Inflammation?
The purpose of this study is to observe a potential benefit of moderate physical activity by using bed mounted cycles during hemodialysis treatment sessions on inflammatory markers in the blood of patients with end-stage renal…
- Trial name
- NCT00893165
- Testing
- moderate physical activity
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Hemodialysis, End Stage Renal Disease (ESRD)
Exploring the Modulatory Effect of the Dialyzer Membrane Choice on Hemodialysisassociated Thromboinflammation: a Prospective Randomized Cross-over Trial
This clinical trial investigates whether the dialyzer membrane influences hemodialysis-associated thromboinflammation. Specifically, it evaluates the effects of 3 commercially available dialyzer membrane types on immune cell…
- Conditions
- Hemodialysis, End Stage Renal Disease (ESRD), Hemodialysis Treatment, Thromboinflammation
- Trial name
- CELL-ACT-MEMBR (NCT07682701)
- Testing
- Use of a polysulfone membrane, Use of an asymmetric triacetate membrane, Use of a polymethyl methacrylate membrane
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Chronic Kidney Disease, Chronic Renal Failure
A Phase 3 Study Comparing the Effects of Intravenous Epoetin Hospira and Epoetin Alfa [Epogen] (Amgen) in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
The purpose of this study is to demonstrate therapeutic equivalence of IV Epoetin Hospira compared to IV Epogen (Amgen), based on maintenance of Hb levels and study drug dose requirements in patients treated for anemia associated…
- Trial name
- AiME - 01 (NCT01473407)
- Testing
- Epoetin Hospira, Epogen (Amgen)
- Where
- 85 sites in United States, Puerto Rico
- Volunteers
- 612 people
- Sponsor
- Pfizer
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