Clinical trials: Esrd
Kidney Failure, Chronic
Exercise Intolerance in Renal Failure
Patients with chronic kidney disease have profound exercise intolerance which contributes to an increased risk of cardiovascular disease.
- Trial name
- EIRF (NCT01356966)
- Testing
- Tetrahydrobiopterin, Folate
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Emory University
Anemia, Kidney Diseases
DELFT (Dynepo Evaluation of Long-Term Follow-Up Treatment)
This is a post-authorisation safety study to assess the incidence and severity of all pre-defined cardiovascular events in patients treated with DYNEPO, as well as to detect \& describe less common adverse drug reactions, and to…
- Conditions
- Anemia, Kidney Diseases, Renal Failure, Chronic, Kidney Failure, Chronic
- Trial name
- DELFT (NCT00664066)
- Testing
- DYNEPO (epoetin delta)
- Where
- 2 sites in Germany
- Volunteers
- 3 people
- Sponsor
- Shire
End-stage Renal Disease
Propaten Randomized Investigation on Cost-benefit and Efficacy
The purpose for this study is to evaluate the patency and outcomes of conventional and heparin anticoagulant bonded arteriovenous grafts in patients with end stage renal disease.
- Trial name
- PRICE (NCT01601873)
- Testing
- PROPATEN, Standard Graft
- Where
- 5 sites in United States
- Volunteers
- 103 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cardiorenal Syndrome
The Effect in Renal Function on Patients With Type 1 Cardiorenal Syndrome Treated With Two Strategies of Furosemide.
In double-blind clinical trial, determine renal recovery with two different furosemide strategies in patients with type 1 cardiorenal syndrome.
- Trial name
- NCT04393493
- Testing
- Furosemide intravenous solution, Chlortalidone, Spironolactone
- Where
- 2 sites in Mexico
- Volunteers
- 80 people
- Sponsor
- Hospital Civil de Guadalajara
Kidney Failure
Sirolimus and Thymoglobulin to Prevent Kidney Transplant Rejection
This study will test the safety and effectiveness of two drugs, Sirolimus and Thymoglobulin, for preventing rejection of transplanted kidneys.
- Trial name
- NCT00006178
- Testing
- Sirolimus, Thymoglobulin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
End Stage Renal Disease
Renal Allograft Tolerance Through Mixed Chimerism
This study will examine the safety and effectiveness of a combination kidney and bone marrow transplant from a haplo-identical related donor.
- Trial name
- NCT01780454
- Testing
- MEDI-507, Rituximab, Total Body Irradiation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Renal Insufficiency, Chronic, Kidney Disease, Chronic
A Study of LY2928057 in Hemodialysis Participants
This study will evaluate the safety of LY2928057 and how LY2928057 affects hemoglobin in hemodialysis participants. This study will involve multiple doses of LY2928057 given during a 6 week period either after a participant…
- Trial name
- NCT01991483
- Testing
- LY2928057
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- Eli Lilly and Company
Renal Insufficiency, Chronic, Hypertension
Supporting Self-Management of Healthy Behaviors in Diabetes, Kidney Disease, and Hypertension
The planned intervention, entitled, Supporting Self-Management of Health Behaviors to Optimize Health (SMART-HABITS for Health), aims to provide support for patients with chronic kidney disease (CKD), hypertension and diabetes by…
- Conditions
- Renal Insufficiency, Chronic, Hypertension, Diabetes
- Trial name
- NCT05565716
- Testing
- Support Person, Social Norms
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Pennsylvania
ESRD, Hyperkalemia
The Effects of Patiromer on Serum Potassium Level and Gut Microbiome of ESRD Patients With Hyperkalemia
The Effects of Patiromer on Serum Potassium Level and Gut Microbiome of ESRD Patients With Hyperkalemia (potassium greater than 5 milliequivalents per liter) is a non-randomized, crossover study.
- Conditions
- ESRD, Hyperkalemia, End Stage Renal Disease
- Trial name
- NCT03326583
- Testing
- Patiromer
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Dominic Raj
End Stage Renal Disease, Kidney Transplantation
Bone Mass and Strength After Kidney Transplantation
The purpose of this study is to test whether active vitamin D (calcitriol) protects bones from weakening and protects blood vessels from calcium deposits over the first year of kidney transplantation.
- Conditions
- End Stage Renal Disease, Kidney Transplantation, Bone Loss, Fractures
- Trial name
- NCT02224144
- Testing
- Vitamin D3, Calcitriol
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Columbia University
Anemia of Chronic Kidney Disease
KRX-0502 (Ferric Citrate) for the Treatment of IDA in Adult Subjects With NDD-CKD
a 24-week phase 3, multi-center clinical trial, comprised of a 16-week, randomized, double-blind, placebo-controlled period ("Randomized Period"), followed by an 8-week open-label safety extension period, where all subjects…
- Trial name
- NCT02268994
- Testing
- ferric citrate
- Where
- 36 sites in United States
- Volunteers
- 234 people
- Sponsor
- Keryx Biopharmaceuticals
Chronic Kidney Disease
Supplementation With Cholecalciferol in Dialysis Patients
Hypovitaminosis D is highly prevalent among patients with chronic kidney disease, especially in those undergoing dialysis. The loss of protein to the dialysis solution seems to contribute significantly to the reduced serum levels…
- Trial name
- NCT01974245
- Testing
- Cholecalciferol
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- Federal University of São Paulo
Acute Kidney Injury
An Electronic Alert System for In-Hospital Acute Kidney Injury
This study will randomize hospitalized patients with acute kidney injury (AKI) to usual care, or an electronic alert intervention.
- Trial name
- NCT01862419
- Testing
- Alert
- Where
- United States
- Volunteers
- 2,393 people
- Sponsor
- University of Pennsylvania
Von-Hippel Lindau, Kidney Disease, Chronic
Contrast-enhanced Ultrasound as a Screening Tool for Kidney Cancer in Patients With Von-Hippel Lindau
The purpose of this study is to determine if contrast-enhanced ultrasound can detect abnormal features of kidney lesions in patients with Von-Hippel Lindau with the same accuracy as conventional ultrasound and contrast-enhanced…
- Trial name
- CEUS-VHL (NCT03907657)
- Testing
- Perflutren lipid microsphere, Sulfur hexafluoride lipid microspheres
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Kidney Transplantation, Kidney Failure, Chronic
Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection
In small initial studies, combined kidney and bone marrow transplants from the same donor have permitted some individuals to stop taking anti-rejection medicines without rejecting their transplant.
- Trial name
- NCT00801632
- Testing
- Kidney Transplantation, Bone marrow transplantation, MEDI-507
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Glargine Versus NPH in Patients With Chronic Kidney Disease
Chronic kidney disease (CKD) is one of the most common microvascular complications of diabetes mellitus, and it is the leading cause of end stage renal disease on developed countries.
- Trial name
- NCT02451917
- Testing
- Glargine insulin, NPH insulin
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Sao Paulo General Hospital
End-Stage Renal Disease (ESRD)
Dose Ranging Study of Dialysate Containing Soluble Iron to Treat Subjects With End Stage Renal Disease (ESRD) Receiving Chronic Hemodialysis
The purpose of this study is to determine whether Dialysate containing soluble iron (Soluble Ferric Pyrophosphate) is safe and effective in maintaining physiological iron levels during chronic hemodialysis.
- Trial name
- NCT00548249
- Testing
- Standard Bicarbonate Solution, Soluble Ferric Pyrophosphate
- Where
- 28 sites in United States, Canada
- Volunteers
- 131 people
- Sponsor
- Rockwell Medical Technologies, Inc.
Kidney Failure, Quality of Life
A Brief Mindful Drinking/Eating Intervention for Hemodialysis Patients With Fluid Restrictions
The purpose of this pilot study is to find out whether mindful drinking/eating activities can improve quality of life and help make it easier for people on dialysis to follow their fluid restrictions.
- Conditions
- Kidney Failure, Quality of Life, Fluid Restriction, Interdialytic Weight Gain
- Trial name
- NCT04016311
- Testing
- Mindful Drinking/Eating Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Texas at Austin
Chronic Renal Insufficiency
Chronic Kidney Disease (CKD) Guideline Adherence - A Quality Improvement Study
Chronic kidney disease (CKD) is defined as kidney damage for greater than 3 months or a glomerular filtration rate less than 60 mL/min per 1.73m2 for greater than 3 months.
- Trial name
- NCT00921687
- Testing
- Education only, Multifactorial intervention
- Where
- United States
- Volunteers
- 781 people
- Sponsor
- Louis Stokes VA Medical Center
Relapsed Multiple Myeloma, End-stage Renal Disease
Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Multiple Myeloma and Renal Disease
The purpose of this study is to see how the body and the cancer react to carfilzomib, including measuring the amount of the study drug in the blood at certain times following dosing.
- Trial name
- NCT01949532
- Testing
- Carfilzomib
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 26 people
- Sponsor
- Amgen
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