Clinical trials: Esrd
Kidney Transplantation, End Stage Kidney Disease (ESRD)
Novel Desensitization Kidney Transplantation
This proposal's objective is to determine whether belatacept, in conjunction with a proteasome inhibitor can be used to safely increase the likelihood of finding an acceptable donor for highly HLA sensitized kidney transplant…
- Trial name
- NCT05345717
- Testing
- Belatacept Injection
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Chicago
End Stage Renal Disease (ESRD), Arteriovenous Fistula Patency
Anesthetic Effect of Ropivacaine on Local Infiltration Anesthesia in Arteriovenous Fistula Surgery
This study compares two local anesthetics, ropivacaine and lidocaine, for patients undergoing arteriovenous fistula surgery. Arteriovenous fistula is the preferred vascular access for end-stage kidney disease patients needing…
- Conditions
- End Stage Renal Disease (ESRD), Arteriovenous Fistula Patency, Chronic Kidney Disease 5D
- Trial name
- NCT07259772
- Testing
- Ropivacaine, Lidocaine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First People's Hospital of Lianyungang
Hypertension, Peritoneal Dialysis
Blood Pressure Control With Thiazide Diuretics in Peritoneal Dialysis Patients
To evaluate the blood pressure lowering effects of thiazide diuretics in patients on peritoneal dialysis
- Conditions
- Hypertension, Peritoneal Dialysis, End Stage Kidney Disease (ESRD)
- Trial name
- NCT07271420
- Testing
- Hydrochlorothiazide 25mg once per day
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
ESRD, CKD Stage 4, CKD Stage 5
Canagliflozin in Advanced Renal Disease With MRI Endpoints
This is a phase II, proof of concept, placebo-controlled, randomized clinical trial, assessing the effect of canagliflozin on cardiac structure and function in patients with advanced renal disease, including those on maintenance…
- Trial name
- CARe-MRI (NCT06182839)
- Testing
- Canagliflozin 300Mg Tab
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
ESRD (End Stage Renal Disease)
Fluid Status of ESRD Patients Undergoing Dialysis
The pilot clinical study will assess the correlation between fluid removal during dialysis and HemoCept device data.
- Trial name
- NCT07217470
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- HemoCept Inc.
End Stage Renal Disease (ESRD), Peritoneal Dialysis Complication
The Effect of Exercise on Low Back Pain in Peritoneal Dialysis Patients
The goal of this randomized controlled trial is to find out if exercise can help reduce low back pain and improve quality of life in people receiving peritoneal dialysis (PD).
- Trial name
- NCT07000006
- Testing
- Home-based Core Stability Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
ESRD (End Stage Renal Disease), Chronic Kidney Disease(CKD)
AP301 Efficacy and Safety in Chinese Dialysis Patients With Hyperphosphatemia
This Phase 3 clinical trial is the pivotal study of AP301 aiming to evaluate the efficacy and safety of AP301 for controlling serum phosphorus in chronic kidney disease receiving hemodialysis and peritoneal dialysis in Chinese…
- Conditions
- ESRD (End Stage Renal Disease), Chronic Kidney Disease(CKD), Hyperphosphatemia, Hyperphosphatemia in Chronic Kidney Disease
- Trial name
- RESPOND-1 (NCT07030595)
- Testing
- AP301, Sevelamer carbonate (Renvela®), AP301 Low Dose
- Where
- 50 sites in China
- Volunteers
- 474 people
- Sponsor
- Alebund Pharmaceuticals
Hemodialysis, Thromboinflammation
Effect of Modifying Magnesium Concentration in Citrate-enriched Dialysate on Hemodialysis-associated Thromboinflammation
This clinical trial investigates whether the composition of dialysate influences hemodialysis-associated thromboinflammation. Specifically, it evaluates the effects of magnesium concentration and acid type in dialysate on immune…
- Conditions
- Hemodialysis, Thromboinflammation, Hemodialysis Complication, End Stage Renal Disease (ESRD)
- Trial name
- pilot OMAGOD + (NCT07206524)
- Testing
- Hemodialysis using dialysate containing citric acid and magnesium at a concentration of 1.0 mmol/L, Hemodialysis using acetic acid dialysate with magnesium 0.5 mmol/L, Hemodialysis using citric acid dialysate with magnesium 0.75 mmol/L
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitair Ziekenhuis Brussel
ESRD (End Stage Renal Disease)
Fluid Status of Dialysis Subjects
The goal of this clinical pilot study is to evaluate the ability of the device to properly detect the hydration status of the subject through the study of fluid removal data during dialysis and HemoCept device data.
- Trial name
- NCT07217041
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- HemoCept Inc.
Complication of Renal Dialysis, End Stage Renal Disease
Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes
The objective of this study is to evaluate efficacy and safety outcomes following use of the Sirolimus-eluting Collagen Implant (SeCI) in subjects undergoing surgical creation of an AV fistula for vascular access (index…
- Conditions
- Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD
- Trial name
- ACCESS (NCT02513303)
- Testing
- Sirolimus, AV Fistula Surgery, Sirolimus-eluting Collagen Implant (SeCI)
- Where
- 4 sites in United States
- Volunteers
- 269 people
- Sponsor
- Vascular Therapies, Inc.
Latent Tuberculosis Infection, End Stage Renal Disease (ESRD)
Prevalence of Latent Tuberculosis Infection Among Hemodialysis Patients
This observational cross-sectional study aims to determine the prevalence of latent tuberculosis infection (LTBI) among patients undergoing regular hemodialysis at Sohag University Hospital, using the tuberculin skin test (TST).
- Conditions
- Latent Tuberculosis Infection, End Stage Renal Disease (ESRD), Hemodialysis
- Trial name
- NCT07210970
- Testing
- Tuberculin Skin Test (TST)
- Volunteers
- 200 people
- Sponsor
- Sohag University
End-stage Renal Disease (ESRD)
Effect of Lifestyle Intervention in Patients With Chronic Kidney Disease on Fitness and Immune Function
To assess the efficacy of a 6-month lifestyle intervention in patients with end-stage renal disease(ESRD), we plan to conduct a self-controlled clinical trial. 34 participants receiving chronic HD will be enrolled.
- Trial name
- NCT05649657
- Testing
- Cyclic aerobic and resistance training
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Kidney Disease Requiring Hemodialysis, End Stage Renal Disease (ESRD)
Early Feasibility Study of the Velocity™ Percutaneous Arterio-Venous Fistula System for Creating Hemodialysis Vascular Access
The Velocity Percutaneous Arterio-Venous System is a minimally invasive method of creating hemodialysis vascular access. The study aims to understand clinical efficacy and initial clinical safety data of the device.
- Trial name
- VENOS-2 (NCT06712251)
- Testing
- Velocity pAVF System
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- Venova Medical
End-stage Renal Disease (ESRD)
Hierarchical Management for Maintenance Hemodialysis Patients
This prospective, randomized controlled trial investigates the effectiveness of a nurse-led, Triangle Hierarchical Management model compared to routine care for patients on maintenance hemodialysis.
- Trial name
- NCT07123168
- Testing
- Triangle Hierarchical Management, routine care
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yanyan Deng
End Stage Renal Disease (ESRD), CKD 5D, Hemodialysis
Activated Charcoal Use in Chronic Kidney Disease Patients
Hyperphosphatemia management is initially based on restricting dietary phosphorus intake. Hyperphosphatemia is almost always seen in patients on dialysis and may contribute to progressive vascular calcification.
- Conditions
- End Stage Renal Disease (ESRD), CKD 5D, Hemodialysis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT06906874
- Testing
- Activated Charcoal, Phosphate Binders
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
ESRD (End Stage Renal Disease), Control Condition
Copper to Zinc Ratio in End Stage Renal Disease Patients Outcome
The goal of this observational clinical trial is to Study the impact of copper to zinc ratio on the outcome of ESRD patients
- Trial name
- NCT07109778
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Minia University
End Stage Renal Disease (ESRD), Diabetes
Dianeal, Extraneal, Nutrineal (D-E-N) Versus Dianeal Only in Diabetic Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients
Primary Objective: To demonstrate that use of glucose sparing prescriptions, Dianeal, Extraneal, Nutrineal (D-E-N) versus Dianeal only, in diabetic (Type 1 and Type 2) Continuous Ambulatory Peritoneal Dialysis (CAPD) patients…
- Conditions
- End Stage Renal Disease (ESRD), Diabetes, CAPD
- Trial name
- EDEN (NCT01219959)
- Testing
- Dianeal, Dianeal, Extraneal, Nutrineal
- Where
- 16 sites in Colombia
- Volunteers
- 71 people
- Sponsor
- Vantive Health LLC
ESRD, Diabetes
IMPENDIA- PEN VS Dianeal Only Improved Metabolic Control In Diabetic CAPD and APD Patients
Primary Objective: To demonstrate that use of glucose sparing prescriptions (PEN vs Dianeal) in diabetic (Type 1 and Type 2) Continuous Ambulatory Peritoneal Dialysis (CAPD)and Automated Peritoneal Dialysis (APD) patients leads…
- Trial name
- Impendia (NCT00567398)
- Testing
- Dianeal, Physioneal, Extraneal
- Where
- 16 sites in Australia, Canada and 1 more
- Volunteers
- 43 people
- Sponsor
- Vantive Health LLC
ESRD, Diabetes
IMPENDIA- PEN VS Dianeal Only Improved Metabolic Control In Diabetic CAPD and APD Patients
Primary Objective: To demonstrate that use of glucose sparing prescriptions (PEN vs Dianeal only) in diabetic (Type 1 and Type 2) Continuous Ambulatory Peritoneal Dialysis (CAPD) and Automated Peritoneal Dialysis (APD)patients…
- Conditions
- ESRD, Diabetes, CAPD, APD
- Trial name
- Impendia (NCT00567489)
- Testing
- Physioneal, Dianeal, Extraneal
- Where
- 19 sites in Hong Kong, Russia and 3 more
- Volunteers
- 137 people
- Sponsor
- Vantive Health LLC
ESRD
Interventions Made to Preserve Cognitive Function
This is a randomized, controlled trial to slow cognitive decline in adults undergoing hemodialysis (HD). The investigators will test three interventions cognitive training (CT), exercise training (ET), and combined cognitive and…
- Trial name
- IMPCT (NCT03616535)
- Testing
- Cognitive training, Exercise training, Combined cognitive and exercise training
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- Johns Hopkins University