Clinical trials: Essential Hypertension.
Hypertension
A Study to Evaluate Efficacy and Safety of HCP1803 Compared to RLD2001-1 in Patients with Essential Hypertension
A multicenter, randomized, double-blind, phase 3 study to evaluate efficacy and safety of HCP1803 compared to RLD2001-1 in patients with essential hypertension
- Trial name
- HM_APOLLO (NCT06438172)
- Testing
- HCP1803-3, RLD2001-1, HPP2003-3
- Where
- South Korea
- Volunteers
- 249 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Postoperative Complications
Effect of Different Anesthetic Techniques for Isolated Systolic Hypertensive Patients of Abdominal Surgery on Postoperative Hospital Stay and Morbidity
In General anesthesia, two main ways of pain control are used intra-operatively, one is opioids, the other is epidural. Many colleges prefer using epidural analgesia because it is potent and more effective , and also the benefits…
- Trial name
- NCT01884298
- Where
- China
- Sponsor
- Peking University First Hospital
Essential Hypertension
The Effect of Eprosartan on Hormones and Kidney Function in Patients With Essential Hypertension
We, the investigators at Holstebro Hospital, want to test the hypothesis that eprosartan reduces the activity of the sympathetic nervous system in patients with essential hypertension - during baseline conditions and after…
- Trial name
- NCT00438945
- Testing
- Eprosartan
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Regional Hospital Holstebro
Hypertension
Effectiveness of Viscum Album Mother Tincture as an Anti-hypertensive in Essential Hypertension
To estimate the effectiveness of Viscum album Homoeopathic mother tincture in Essential Hypertension by conducting clinical trial in moderate hypertensive patients for a period of six weeks.
- Trial name
- NCT01527760
- Testing
- Viscum album ethanolic extract manufactured according to Homoeopathic pharmacopoeia of India (H.P.I.)
- Where
- India
- Volunteers
- 37 people
- Sponsor
- Fr Muller Homoeopathic Medical College
Essential Hypertension
Compliance of Patients With Essential Hypertension Treated With Candesartan or Candesartan/Hydrochlorothiazide
The CoCa study with at maximum daily dose of 32 mg candesartan or 16/12.5 mg candesartan/hydrochlorothiazide has the objective to evaluate under naturalistic conditions, i.e.
- Trial name
- CoCa (NCT00608153)
- Volunteers
- 1,773 people
- Sponsor
- AstraZeneca
Cardiovascular Disease
STRETCH Study: Effect of Distensibility on Endothelial-Dependent Vasoreactivity in Patients With ISH
Determine whether increasing arterial distensibility by decreasing advanced glycation end-product (AGE) cross-link components of vascular stiffness improves (a) endothelial-mediated vasoreactivity at rest, as assessed by…
- Trial name
- NCT00277875
- Testing
- ALT-711 (alagebrium chloride)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Synvista Therapeutics, Inc
Hypertension
A Study of VAH631 in Patients With Essential Hypertension (Factorial Study)
The purpose of this study is to compare the effect of the fixed combination of valsartan+hydrochlorothiazide (HCTZ) on blood pressure reduction with valsartan and HCTZ alone and whether the combination treatments are safe and…
- Trial name
- NCT00311740
- Testing
- Valsartan, Hydrochlorothiazide
- Where
- Japan
- Volunteers
- 582 people
- Sponsor
- Novartis
Hypertension
Effects of Dark Chocolate on Insulin Sensitivity in People With High Blood Pressure
This study will examine whether dark chocolate affects the way patients with hypertension (high blood pressure) respond to insulin, a hormone secreted by the pancreas that regulates blood glucose (sugar) levels.
- Trial name
- NCT00099476
- Testing
- Effects of dark chocolate
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Hypertension, Postmenopause
Effect of Angeliq on Blood Pressure (BP) in Postmenopausal Hypertensive Women
The objective of the study is to evaluate the effects of Angeliq on BP over a period of 8 weeks in postmenopausal women who may benefit from hormone replacement therapy (HRT) for the relief of vasomotor symptoms and who have…
- Trial name
- NCT00102141
- Testing
- Angeliq (Drospirenone/17ß-estradiol, BAY86-4891)
- Volunteers
- 750 people
- Sponsor
- Bayer
Hypertension
BRAVE Study With Uncontrolled Essential Hypertension (BRAVE Study)
This is an open-label, placebo run-in study to investigate the genetic and biomedical predictors of blood pressure response to bisoprolol.
- Trial name
- BRAVE (NCT02398929)
- Testing
- Bisoprolol 2.5 mg
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis, Hypertension
To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension
To assess the effect of naproxcinod vs. naproxen and ibuprofen on arterial blood pressure in patients with osteoarthritis and controlled essential hypertension
- Trial name
- HCT3012-X-112 (NCT00662896)
- Testing
- naproxcinod 375 mg bid, naproxcinod 750 mg bid, naproxen 250 mg bid
- Where
- 57 sites in United States
- Volunteers
- 300 people
- Sponsor
- NicOx
Essential Hypertension, Metabolic Syndrome
Vascular Impact of Omega-3 in Metabolic Syndrome
The overall aims of the present project are to investigate the impact of a nutritional approach based on omega-3 from vegetal origin on vascular function in hypertension associated with metabolic syndrome.
- Trial name
- CARDIOMEGA (NCT01566188)
- Testing
- omega-3 from vegetal origin
- Where
- 4 sites in France
- Volunteers
- 95 people
- Sponsor
- University Hospital, Rouen
Essential Hypertension
In-practice Evaluation of Atacand 16mg Antihypertensive Effect
The purpose of this study is to prove in practice the effectiveness of Atacand 16 mg in reducing blood pressure after 4 weeks of administration and the importance of administration of adequate doses
- Trial name
- NCT00802542
- Where
- 4 sites in Latvia
- Volunteers
- 400 people
- Sponsor
- AstraZeneca
Hypertension
Renal Sympathectomy in Treatment Resistant Essential Hypertension, a Sham Controlled Randomized Trial
The purpose of this double blind, randomized and sham controlled study is to determine whether renal denervation in terms of catheter based ablation in the renal arteries is effective in lowering blood pressure in patients with…
- Trial name
- ReSET (NCT01459900)
- Testing
- Renal artery ablation, Renal angiography
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- Aarhus University Hospital Skejby
Essential Hypertension
Efficacy and Safety of LCZ696 200 mg + Amlodipine 5 mg in Comparison With Amlodipine 5 mg in Hypertensive Patients Not Responding to Amlodipine
This study will assess whether LCZ696 when used in combination with amlodipine will provide greater BP lowering benefit compared to amlodipine alone in Asian hypertensive patients not adequately responsive to amlodipine therapy.
- Trial name
- NCT01663233
- Testing
- LCZ696, Amlodipine
- Where
- 28 sites in China, Japan and 4 more
- Volunteers
- 266 people
- Sponsor
- Novartis Pharmaceuticals
High Blood Pressure (& [Essential Hypertension]), Motivation for Physical Activity
Instructor Interpersonal Behaviours in Classical Pilates as a Pathway to Improve Blood Pressure Control and Well-being in Hypertensive Adults
The aim of this study is to investigate, during a Classical Pilates programme with participants suffering from high blood pressure, whether supportive communication from the instructor to the participant has any effect on the…
- Conditions
- High Blood Pressure (& [Essential Hypertension]), Motivation for Physical Activity, Pilates Method, Interpersonal Communication Competence
- Trial name
- NCT07860437
- Testing
- Self-Determination Theory Based Supportive Communication, Control
- Where
- Portugal
- Volunteers
- 96 people
- Sponsor
- Instituto Politécnico de Leiria
Uncontrolled Hypertension
A Phase I Trial of QLS1410 in Healthy Chinese Adults and Participants With Mild Essential Hypertension
The goal of this clinical trial is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and food effect of single and multiple ascending doses of QLS1410 in healthy Chinese adults and participants with mild…
- Trial name
- NCT07152444
- Testing
- QLS1410 (CYP11B2 inhibitor)
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Hypertension, Dyslipidemias
Observational Study to Investigate the Effectiveness and Safety of Olostar Tab in Patients With Essential Hypertension and Dyslipidemia
The purpose of this study is to investigate the effectiveness and safety of Olostar Tab in patients with essential hypertension and dyslipidemia
- Trial name
- NCT03009721
- Testing
- Other: Not applicable-observational study
- Where
- South Korea
- Volunteers
- 9,707 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Primary Hypertension
A National Multicentre Study to Assess the Efficacy of the Fixed Combination of Valsartan and Amlodipine in Hypertensive Patients Not Controlled by Monotherapy
This study is to assess the efficacy of the fixed combination of Valsartan and Amlodipine in hypertensive patients uncontrolled by monotherapy.
- Trial name
- NCT01241487
- Testing
- valsartan/amlodipine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Novartis
Diabetes Mellitus, Essential Hypertension
The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension
The objective of this study is to investigate the effect of metformin on the correlation between hyperinsulinemia and hypertension.
- Trial name
- NCT01342614
- Testing
- Fosinopril, Metformin
- Volunteers
- 140 people
- Sponsor
- China-Japan Friendship Hospital