Clinical trials: Essential Hypertension.
Hypertension
Effect of Gene Variants on Dopamine Receptor Natriuretic Responses
Hypothesis to be tested: Dopamine D1-like receptor-induced natriuresis is impaired in humans with G protein-related kinase 4 gene variants.
- Trial name
- NCT00592150
- Testing
- fenoldopam
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Essential Hypertension, Type 2 Diabetes Mellitus
A Study to Evaluate the Efficacy and Safety of BR1019A and BR1019B Combination Therapy
The objective of this clinical study is to Evaluate the Efficacy and Safety of BR1019A and BR1019B combination therapy in Patients with Essential Hypertension and Type 2 Diabetes Mellitus
- Trial name
- NCT06220773
- Testing
- BR1019A, BR1019B, BR1019C
- Where
- 3 sites in Indonesia, South Korea
- Volunteers
- 276 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Essential Hypertension
A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure Following Treatment With Azilsartan Medoxomil Alone
The purpose of this study is to evaluate the efficacy and safety of the fixed dose combinations of azilsartan medoxomil plus chlorthalidone (40/12.5 and 40/25 mg), once daily, in participants with grades 2 or 3 essential…
- Trial name
- NCT01456169
- Testing
- Azilsartan medoxomil - chlorthalidone
- Where
- 108 sites in Bulgaria, Estonia and 12 more
- Volunteers
- 507 people
- Sponsor
- Takeda
Essential Hypertension
Study of Personalized Dietary Intervention for the Control of Essential Hypertension
An ongoing case study of psoriasis, shows reproducibly that ingestion of hydrogenated fats, and some flavourant or sweetener compounds, leads to relapse of psoriasis, and secondary food intolerances, followed by remission over a…
- Trial name
- PCFADASH-HT (NCT02136264)
- Testing
- PCFA interventional dietary counselling, conventional DASH diet counselling
- Where
- Nigeria
- Volunteers
- 50 people
- Sponsor
- University of Nigeria, Enugu Campus
Primary Hypertension, Secondary Hypertension
HaemoDYNAMICs in Primary and Secondary Hypertension
The primary aim of the present study was to examine the haemodynamic changes in primary hypertension and secondary hypertension (renal diseases, endocrine diseases, obesity-associated hypertension) with a non-invasive…
- Conditions
- Primary Hypertension, Secondary Hypertension, Aortic Stenosis, Renal Insufficiency
- Trial name
- DYNAMIC (NCT01742702)
- Testing
- Nitroglycerin 0.25 mg (single dose, no longer given since January 2017), Salbutamol 400 µg (single dose, no longer given since January 2017), L-arginine (10 min infusion, no longer given since January 2017)
- Where
- 2 sites in Finland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tampere University
Hypertension, Essential (Primary) Hypertension
Effect of the Traditional Chinese Medicine Yufeng Ningxin in Patients With Hypertension
Yufeng Ningxin, a traditional Chinese medicine, has demonstrated potential antihypertensive effects in animal studies and small clinical trials, but has not yet been rigorously evaluated in large randomized clinical trials.
- Trial name
- NCT07607275
- Testing
- Yufeng Ningxin tablets
- Where
- 16 sites in China
- Volunteers
- 350 people
- Sponsor
- Beijing Anzhen Hospital
Essential Hypertension
Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension
To examine antihypertensive effect, pharmacodynamics, and safety of long-term administration of CS-3150 as monotherapy and in combination with calcium channel blocker or renin-angiotensin system inhibitor in patients with…
- Trial name
- NCT02722265
- Testing
- CS-3150
- Where
- Japan
- Volunteers
- 368 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Hypertension,Essential, Hypertension
Recreational Futsal for Controlled Hypertension
Arterial hypertension (HT) was the leading global contributor for premature deaths in 2015. Its treatment includes medication and lifestyle changes, namely diet and regular exercise, which has shown to have an inverse…
- Conditions
- Hypertension,Essential, Hypertension, Blood Pressure Disorders, Blood Pressure
- Trial name
- HyperFut (NCT05185297)
- Testing
- Recreational Futsal
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- University Institute of Maia
Hypertension
A Study to Evaluate Efficacy and Safety of HCP1803 in Patients With Essential Hypertension
A multicenter, randomized, double-blind, phase 3 study to evaluate efficacy and safety of HCP1803 in patients with essential hypertension
- Trial name
- HM_APOLLO (NCT05362110)
- Testing
- HCP1803-3, RLD2002, HPP2003-3
- Where
- South Korea
- Volunteers
- 361 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Hypertension, Stroke
A Blood Pressure Regulation and Stroke Risk Evaluation Study in Hypertensive Patients Treated With Eprosartan
The primary objective of the study is to evaluate the proportion of hypertensive patients who achieve regulation of their blood pressure (BP) levels according to the European Society of Cardiology / European School of Haematology…
- Trial name
- NCT01562613
- Where
- 84 sites in Greece
- Volunteers
- 533 people
- Sponsor
- Abbott
Essential Hypertension, Primary Hypercholesterolemia
A Study to Evaluate the Efficacy and Safety of Co-administrated BR1018B and BR1018C
The purpose of this clinical trial is to evaluate the efficacy and safety of co-administrated BR1018B and BR1018C in patients with essential hypertension and primary hypercholesterolemia
- Trial name
- NCT06165250
- Testing
- BR1018A, BR1018A-1, BR1018B
- Where
- 2 sites in South Korea
- Volunteers
- 151 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension
Study Comparing SPP100 (Aliskiren) 150mg to Placebo and to Losartan 50mg in Patients With Mild to Moderate Essential Hypertension
Assessing efficacy, safety and pharmacokinetics in patients with mild to moderate essential hypertension
- Trial name
- NCT00344110
- Testing
- Aliskiren
- Where
- Japan
- Volunteers
- 768 people
- Sponsor
- Novartis
Essential Hypertension
Safety, Tolerability, Pharmacodynamic Effects and Preliminary Evidence for Efficacy of the Anti-Hypertension Vaccine CYT006-AngQb
This is a multi-center, randomized, placebo-controlled, time-lagged, parallel-group study in healthy and hypertensive subjects to evaluate safety and tolerability of the vaccine CYT006-AngQb.
- Trial name
- NCT00500786
- Testing
- CYT006-AngQb
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cytos Biotechnology AG
Hypertension
Clinical Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Hydrochlorothiazide in Patients With Essential Hypertension.
To demonstrate the efficacy and safety of aliskiren given to patients with essential hypertension, at doses of 75 mg, 150 mg and 300 mg alone, and in combination with hydrochlorothiazide (HCTZ)
- Trial name
- NCT00219024
- Testing
- aliskiren
- Where
- 2 sites in United States, Germany
- Volunteers
- 2,775 people
- Sponsor
- Novartis
Hypertension
Micardis®. Observational Study in Patients With Essential Hypertension
This study is designed to supplement, under conditions of usual clinical practice, the data on the efficacy and safety of Micardis® collected during the clinical studies.
- Trial name
- NCT02200094
- Testing
- Low dose of Telmisartan, once daily, High dose of Telmisartan, once daily
- Volunteers
- 4,532 people
- Sponsor
- Boehringer Ingelheim
Hypertensive Urgency, Primary Hypertension
The Use of Virtual Reality and Music Therapy for Hypertensive Urgency
This study aims to evaluate whether virtual reality (VR) and classical music therapy, when added to standard antihypertensive treatment, can improve blood pressure control and reduce anxiety in patients presenting to the…
- Trial name
- NCT07272486
- Testing
- Captopril 25Mg Tab, Virtual Reality Exposure, Classic Music Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ankara City Hospital Bilkent
Hypertension
Clinical Efficacy and Safety Evaluation of HCP1904-3 in Essential Hypertension Patients
The purpose of this study is to evaluate of efficacy and safety of HCP1904-3 and RLD2001-1 alone in patients with essential hypertension inadequately controlled on RLD2001-1 monotherapy.
- Trial name
- NCT05199129
- Testing
- HCP1904-3, RLD2001-1
- Where
- South Korea
- Volunteers
- 166 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Pregnancy-Associated Hypertension, Gestational Hypertension
Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure
High blood pressure during or after pregnancy (such as preeclampsia, gestational hypertension, eclampsia, or Hemolysis, Elevated Liver enzymes, and Low Platelet (HELLP) syndrome) raises a mother's risk of heart disease later in…
- Conditions
- Pregnancy-Associated Hypertension, Gestational Hypertension, Preeclampsia, Eclampsia
- Trial name
- AW2H (NCT07778966)
- Testing
- Alabama Womb to Heart Solution (AW2H) Community Health Worker (CHW) Program, Usual postpartum care with self-measured blood pressure education and home blood pressure monitor
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- University of Alabama at Birmingham
Isolated Systolic Hypertension
Blood Pressure and Lipids Reduction in High Risk Elderly Patients With Isolated Systolic Hypertension
1. Study name: Blood Pressure and Lipids Reduction in High Risk Elderly Patients with Isolated Systolic Hypertension. 2. Medicine: amlodipine/atorvastatin tablet (5mg/10mg) and amlodipine (5mg). 3.
- Trial name
- NCT05165251
- Testing
- Amlodipine/Atorvastatin 5 Mg-10 Mg ORAL TABLET, Amlodipine 5mg, Lifestyle intervention
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Cardiovascular Diseases, Heart Diseases
Molecular Epidemiology of Essential Hypertension
To localize individual genes, called blood pressure quantitative trait genes [BPQTGs], which influence blood pressure levels in the population-at- large, and to determine if these genes are able to predict the occurrence of…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Hypertension
- Trial name
- NCT00005377
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston