Clinical trials: Essential Hypertension.
Hypertension,Essential
A Study to Evaluate the Efficacy and Safety of AD-224
The purpose of this study is to evaluate the efficacy and safety of AD-224
- Trial name
- NCT06291207
- Testing
- AD-224A, AD-224B, AD-224C
- Where
- South Korea
- Volunteers
- 254 people
- Sponsor
- Addpharma Inc.
Hypertension
Salt Intake and Blood Pressure Control in Adults With Essential Hypertension
The goal of this study is to explore the barriers and facilitators to adopting a reduced dietary salt and increased potassium intake among adults with essential hypertension in Singapore, and to evaluate the feasibility and…
- Trial name
- NCT07025928
- Testing
- Decreased Salt High Potassium Tool (DSHP Tool)
- Where
- Singapore
- Volunteers
- 190 people
- Sponsor
- Sun Jingfeng
Primary Aldosteronism, Essential Hypertension
Microvascular Function in Primary Aldosteronism
Patients with primary aldosteronism, which is the most prevalent form of secondary hypertension, have an increased rate of cardiovascular events, compared to patients with essential hypertension, even with equal severity of…
- Trial name
- NCT02096939
- Testing
- Adrenal extirpation, Antihypertensive medication
- Sponsor
- Maastricht University Medical Center
Essential Hypertension
Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy
Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy
- Trial name
- NCT05931224
- Where
- South Korea
- Volunteers
- 346 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Elevated Triglycerides, Systolic Hypertension
A Pilot Study to Determine the Efficacy of a Low Carbohydrate Diet in Treatment of Adolescents With Metabolic Syndrome
The purpose of this study is to determine the effectiveness of two different non-energy restricted controlled carbohydrate programs with the American Diabetes Associations' diet on glycosylated hemoglobin and other diabetes risk…
- Conditions
- Elevated Triglycerides, Systolic Hypertension, Insulin Resistance, Abdominal Obesity
- Trial name
- NCT00940966
- Testing
- standard ADA diet, energy restricted very-low carbohydrate diet, low glycemic diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- CAMC Health System
Essential Hypertension, Motivational Interview
Effect of Motivational Interviews on Cardiovascular Disease Risks and Healthy Lifestyle Behavior Changes
The primary aim of this study is to determine the effects of education and motivational interviews structured according to the health belief model on cardiovascular disease risks and healthy lifestyle behavior changes in patients…
- Conditions
- Essential Hypertension, Motivational Interview, Cardiovascular Disease Risk, Healthy Lifestyle Behavior
- Trial name
- NCT05390931
- Testing
- 6-session motivational interviews, Health education structured according to the health belief model, Training booklet prepared by the researchers on healthy lifestyle behavior changes
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Eskisehir Osmangazi University
Essential Hypertension
Fimasartan (BR-A-657) Single Oral Dose in Healthy Subjects
The objective of this study is to determine the safety and tolerability and to determine the Pharmacokinetic and Pharmacodynamic (PK/PD) of ascending single oral dose of BR-A-657 in healthy male subjects.
- Trial name
- NCT01289886
- Testing
- BR-A-657
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension
A Study to Evaluate the Combination of Valsartan + Amlodipine in Hypertensive Patients
The purpose of this study is to evaluate the efficacy of valsartan plus amlodipine in hypertensive patients not responding to treatment with amlodipine or felodipine alone.
- Trial name
- NCT00392262
- Testing
- valsartan + amlodipine
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 224 people
- Sponsor
- Novartis
Essential Hypertension
L-Arginine Metabolism in Essential Hypertension
Essential hypertension is characterized by impaired endothelial function. Data derived from normotensive subjects with a genetic predisposition to arterial hypertension suggest that endothelial dysfunction is a cause rather than…
- Trial name
- NCT00137124
- Testing
- L-Arginine
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hypertension
Post-Marketing Surveillance Of Olmesartan Medoxomil In Combination With Hydrochlorothiazide
This is a Post-Marketing Surveillance study evaluating the Efficacy, Tolerability and Safety of Olmesartan medoxomil 20 mg in combination with 12.5 MG of hydrochlorothiazide in subjects with mild to moderate essential hypertension
- Trial name
- NCT00796159
- Testing
- Olmesartan medoxomil
- Volunteers
- 1,723 people
- Sponsor
- Pfizer
Essential Hypertension, Renal Impairment
Olmesartan Medoxomil in Hypertension and Renal Impairment
This is a study in hypertensive patients with mild to moderate renal impairment. The antihypertensive efficacy of olmesartan medoxomil is compared to losartan.
- Trial name
- NCT00151827
- Testing
- Olmesartan medoxomil, Losartan, Furosemide oral tablets
- Where
- Germany
- Volunteers
- 393 people
- Sponsor
- Sankyo Pharma Gmbh
Hypertension,Essential
Safety and Efficacy of SPH3127 on Treating Mild-moderate Essential Hypertension Patients
SPH3127 tablet is a of renin inhibitor. It is expected to be a new drug for essential hypertension. This is a phase IIa trial which designed to evaluate its efficacy and safety on treating mild-moderate essential hypertension…
- Trial name
- NCT03756103
- Testing
- SPH3127 tablet Dose 1, SPH3127 tablet Dose 2, SPH3127 tablet Dose 3
- Where
- 10 sites in China
- Volunteers
- 120 people
- Sponsor
- Shanghai Pharmaceuticals Holding Co., Ltd
Hypertension
Effectiveness of Viscum Album Mother Tincture as an Anti-hypertensive in Essential Hypertension
To estimate the effectiveness of Viscum album Homoeopathic mother tincture in Essential Hypertension by conducting clinical trial in moderate hypertensive patients for a period of six weeks.
- Trial name
- NCT01527760
- Testing
- Viscum album ethanolic extract manufactured according to Homoeopathic pharmacopoeia of India (H.P.I.)
- Where
- India
- Volunteers
- 37 people
- Sponsor
- Fr Muller Homoeopathic Medical College
Essential Hypertension
Protective Effect of Beraprost Sodium Tablets on Reperfusion Therapy for Acute STEMI
Protective effect of Beraprost Sodium Tablets on coronary microcirculation function and ventricular remodeling after reperfusion therapy for acute ST segment elevation myocardial infarction
- Trial name
- NCT05103813
- Testing
- Beraprost Sodium Tablets
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shenzhen People's Hospital
Hypertension
Low-dose Nifedipine-Valsartan Combination Compared to Up-titrated Valsartan Monotherapy in Essential Hypertension
This will be a multi-center, prospective, randomized, open-label, parallel design, two arm comparator trial. In the proposed study, the investigators will compare low-dose combination therapy of Nifedipine GITS/OROS plus…
- Trial name
- NCT00993109
- Testing
- Adalat (Nifedipine, BAYA1040), Diovan (Valsartan)
- Where
- 17 sites in China, South Korea
- Volunteers
- 360 people
- Sponsor
- Bayer
Systolic Hypertension, Pregnancy Related
Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy
The purpose of the research is to characterize the effect of labetalol, atenolol, and nifedipine on maternal hemodynamics early in pregnancy.
- Conditions
- Systolic Hypertension, Pregnancy Related, Diastolic Hypertension, Cardiac Output, Low
- Trial name
- NCT04755764
- Testing
- Labetalol, Atenolol, Nifedipine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marshall University
Essential Hypertension
Efficacy and Safety of Arotinolol Hydrochloride on Morning Blood Pressure and Heart Rate
The purpose of this study is to compare the efficacy and safety of Arotinolol Hydrochloride and Metoprolol succinate on morning blood pressure, heart rate and target organ damage in patients with essential hypertension.
- Trial name
- ESAHOM (NCT02612298)
- Testing
- Arotinolol Hydrochloride, Metoprolol succinate sustained-release tablet
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Marubeni Pharmaceuticals (Suzhou) Co., Ltd.
Hypertension
Efficacy and Safety of Carvedilol SR Versus Carvedilol IR in Patients With Essential Hypertension
The aim of present study is to evaluate the efficacy and safety of Carvedilol SR versus Carvedilol IR in Patients With Essential Hypertension
- Trial name
- NCT01756430
- Testing
- Carvedilol SR 32mg, QD, Carvedilol SR 64mg, QD, Carvedilol IR 25mg, QD
- Where
- South Korea
- Volunteers
- 238 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension
Efficacy and Safety of Moxonidine in Indian Patients
The purpose of this study is to demonstrate efficacy and safety of Moxonidine in Indian subjects.
- Trial name
- NCT00160277
- Testing
- Moxonidine
- Where
- 3 sites in India
- Volunteers
- 100 people
- Sponsor
- Solvay Pharmaceuticals
Essential Hypertension
Study to Compare and Assess the Safety and Pharmacokinetic Characteristics After Oral Administration of Fimasartan (BR-A-657∙K) in Healthy Elderly and Young Male Volunteers
The purpose of this study is to compare and assess the safety and pharmacokinetic characteristics after oral administration of fimasartan (BR-A-657∙K) in healthy elderly and young male volunteers.
- Trial name
- Fimasartan (NCT00937534)
- Testing
- Fimasartan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd