Clinical trials: Essential Hypertension.
Hypertension
A Study to Compare COREG CR to COREG CR Fixed-dose Combination in Patients With High Blood Pressure
Carvedilol controlled release is a marketed drug to treat high blood pressure. This study is to compare carvedilol controlled release to carvedilol controlled release plus lisinopril (fixed-dose combination) after repeat dosing…
- Trial name
- NCT00537043
- Testing
- SK&F-105517 (COREG CR FDC)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- GlaxoSmithKline
Hypertension
An Examination of the Safety and Blood Pressure Lowering Effect of Increasing Doses of Benicar® and Benicar® HCT in Patients With Hypertension
Effect of increasing doses of olmesartan medoxomil and olmesartan medoxomil/hydrochlorothiazide on blood pressure in patients with hypertension
- Trial name
- NCT00185068
- Testing
- Olmesartan medoxomil, Olmesartan medoxomil/hydrochlorothiazide, Hydrochlorothiazide
- Where
- 16 sites in United States
- Volunteers
- 110 people
- Sponsor
- Daiichi Sankyo
Hypertension
Efficacy and Safety of Aliskiren 75 mg, 150 mg, and 300 mg in Elderly Patients With Essential Hypertension When Given With a Light Meal in a 8 Week Placebo-controlled Study
This study will evaluate the efficacy and safety of aliskiren 75 mg, 150 mg, and 300 mg in elderly patients with essential hypertension when given with a light meal.
- Trial name
- NCT00706134
- Testing
- Aliskiren 75 mg, Aliskiren 150 mg, Aliskiren 300 mg
- Where
- 8 sites in Argentina, Czechia and 6 more
- Volunteers
- 756 people
- Sponsor
- Novartis
Essential Hypertension, Hepatic Impairment
A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Hepatic Impairment Patients and Healthy Volunteers
To compare and evaluate the pharmacokinetic characteristics and the safety of fimasartan in hepatic impairment patients and healthy volunteers
- Trial name
- NCT01146938
- Testing
- fimasartan
- Where
- South Korea
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension
Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential Hypertension
The purpose of this study is to determine the efficacy and safety of azilsartan medoxomil, once daily (QD), compared to ramipril for treating Essential Hypertension.
- Trial name
- NCT00760214
- Testing
- Azilsartan medoxomil, Ramipril
- Where
- 72 sites in Bulgaria, Estonia and 8 more
- Volunteers
- 885 people
- Sponsor
- Takeda
Coronary Heart Disease, Essential Hypertension
Danshen Dropping Pill for Coronary Heart Disease Heart and Artery Structure and Function
The Impact of Compound danshen dropping pill for coronary heart disease (CHD) heart and artery structure and function in patients with hypertension
- Trial name
- NCT01825759
- Testing
- danshen dripping pill
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Essential Hypertension
Efficacy and Safety of Azilsartan Compared to Olmesartan Medoxomil in Chinese Participants With Grade I or II Essential Hypertension
To investigate the efficacy and safety of azilsartan compared to olmesartan medoxomil in patients with grade I or II essential hypertension
- Trial name
- NCT02407210
- Testing
- azilsartan, Olmesartan medoxomil
- Where
- China
- Volunteers
- 304 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Essential Hypertension
NW Roselle in Grade 1 Essential Hypertension: Phase III Clinical Trial
In this Phase III clinical trial, researchers evaluate the efficacy and safety of NW Roselle®, a powdered medicinal product developed by Natural Wellness.
- Trial name
- NCT06141200
- Testing
- NW Roselle, Captopril 25Mg Tab
- Volunteers
- 286 people
- Sponsor
- Natural Wellness Egypt
Essential Hypertension
Amlodipine as add-on to Olmesartan in Hypertension
Test the efficacy and safety of the combination of olmesartan and amlodipine in hypertensive patients whose blood pressure is not adequately controlled with olmesartan alone.
- Trial name
- NCT00220220
- Testing
- olmesartan medoxomil, amlodipine
- Where
- 6 sites in Germany
- Volunteers
- 429 people
- Sponsor
- Sankyo Pharma Gmbh
Essential Hypertension
Comparison of Efficacy and Safety of Combination Therapy and Monotherapy of Candesartan and Amlodipine for Dose-Finding in Patients With Essential Hypertension
The purpose of this study is to explore the optimal dose of fixed-dose combination of candesartan cilexetil and amlodipine besylate by examining the safety and efficacy of the combination therapy compared to each of the…
- Trial name
- NCT02944734
- Testing
- Candesartan Cilexetil 8mg, Candesartan Cilexetil 16mg, Amlodipine 5mg
- Where
- 23 sites in South Korea
- Volunteers
- 392 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Hypertension
Telmisartan Compared to Losartan + Hydrochlorothiazide in Patients With Mild-to-moderate Essential Hypertension
The general aim and clinical objective of this trial is to determine the effect of telmisartan 80 mg compared to losartan 50 mg + HCTZ (Hydrochlorothiazide) 12.5 mg on reduction of blood pressure (BP) in patients with mild to…
- Trial name
- NCT02183701
- Testing
- Telmisartan, Losartan + Hydrochlorothiazide
- Volunteers
- 715 people
- Sponsor
- Boehringer Ingelheim
Hypertension
The Effects on Blood Pressure Control, Pulse Wave Velocity, as Well as Safety and Tolerability of Felodipine Sustained Release in Chinese Patients.
The purpose of this study is to evaluate the effects on blood pressure control, pulse wave velocity, as well as safety and tolerability of felodipine single or combine with other drugs in Chinese Hypertension patients.
- Trial name
- NCT02336607
- Testing
- Felodipine tablet (Plendil) alone, Felodipine tablet (Plendil)+Hydrochlorothiazide, Felodipine tablet (Plendil)+Metoprolol tablet (Betaloc ZOK)
- Volunteers
- 529 people
- Sponsor
- AstraZeneca
Hypertension, Left Ventricular Hypertrophy
Evaluation of Regional Myocardial Dynamics at Physical Stress in Essential Hypertension
The study hypothesis is stress-related regional tissue dynamics is related to left ventricular outflow tract blood flow.
- Trial name
- NCT01442116
- Testing
- stress echocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mustafa Kemal University
Diabetic Kidney Disease, Proteinuria
An Observation Study to Evaluate the Renoprotective Effect of Fimasartan in Patients With DKD and Proteinuria
This study aims to observe changes in various indicators of renal function, such as proteinuria at different time points: short-term (Week 8), 6 months (Week 26), and a year (Week 52), in patients with DKD and hypertension, who…
- Conditions
- Diabetic Kidney Disease, Proteinuria, Hypertension,Essential
- Trial name
- FINALE (NCT05086549)
- Where
- South Korea
- Volunteers
- 360 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Essential Hypertension
Clinical Trial to Evaluate the Antihypertensive Effect of AGSCT101 in Patient With Hypertension
The purpose of this study is to evaluate the antihypertensive effect of AGSCT101 tablet in patient with stage 1 to 2 essential hypertension.
- Trial name
- NCT01413048
- Testing
- Carvedilol 25mg, AGSCT101 12.5mg
- Where
- South Korea
- Volunteers
- 260 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Essential Untreated Hypertension, Healthy Volunteers
Comparison of Ultrafast Echo With Echotracking
The aim is to compare a new technique for assessing mechanical properties of large arteries: the Ultrafast echo with the reference technique, the echotracking.
- Trial name
- NCT01743352
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- French Cardiology Society
Primary Hypercholesterolemia, Hypertension
To Evaluate the Efficacy and Safety of Co-administrated Ezetimibe/Rosuvastatin and Telmisartan in Patients With Essential Hypertension and Primary Hypercholesterolemia
This study is a multicenter, Randomized, double-blind, acitve-controlled, Phase 3 Clinical Trial in 8 weeks for screening, twice Investigational product administer, Follow up visit.
- Trial name
- NCT04659070
- Testing
- Experimental : Ezetimibe / Rosuvastatin + Telmisartan, Active comparator1 : Ezetimibe / Rosuvastatin, Active comparator2 : Telmisartan
- Where
- South Korea
- Volunteers
- 156 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Isolated Systolic Hypertension
Systolic Hypertension in Europe Placebo-Controlled Trial
The Syst-Eur Trial is a concerted action of the European Community's Medical and Health Research Programme. The trial is carried out in consultation with the World Health Organization, the International Society of Hypertension…
- Trial name
- Syst-Eur (NCT02088450)
- Testing
- Active treatment with nitrendipine (10-40 mg/day).
- Volunteers
- 4,695 people
- Sponsor
- KU Leuven
Hypertension, Stroke
Recurrent Stroke Prevention Clinical Outcome Study
1. Objectives and Hypothesis 1. Objectives: This study evaluates whether strict BP management is useful for the prevention of recurrent stroke.
- Conditions
- Hypertension, Stroke, Blood Pressure
- Trial name
- RESPECTS (NCT01198496)
- Testing
- Losartan, Losartan and HCTZ, Amlodipine , Spironolactone
- Where
- Japan
- Volunteers
- 5,000 people
- Sponsor
- Biomedis International Ltd.
Essential Hypertension
Olmesartan Medoxomil Versus Losartan in Elderly and Very Elderly
To assess the efficacy of individually optimized doses of olmesartan medoxomil compared to losartan in elderly and very elderly patients with essential hypertension.
- Trial name
- NCT00751751
- Testing
- olmesartan medoxomil + hydrochlorothiazide, if necessary, losartan + hydrochlorothiazide, if necessary
- Where
- Germany
- Volunteers
- 441 people
- Sponsor
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company