Clinical trials: Essential Hypertension.
Hypertension
Combination of Telmisartan 40 mg Plus Hydrochlorothiazide (HCTZ) 12.5 mg vs. Telmisartan 40 mg Alone in Patients With Essential Hypertension Who Fail to Respond Adequately to Telmisartan Monotherapy
The objective of this trial is to demonstrate that the fixed dose combination of telmisartan 40 mg and HCTZ 12.5 mg is superior to the monocomponent of telmisartan (Micardis, Gliosartan, Kinzal, Kinzalmono, Predxal, Pritor…
- Trial name
- NCT00144222
- Testing
- Telmisartan 40 mg/HCTZ 12.5 mg, Telmisartan 40 mg
- Where
- 2 sites in Japan
- Volunteers
- 218 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Clinical Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Hydrochlorothiazide in Patients With Essential Hypertension.
To demonstrate the efficacy and safety of aliskiren given to patients with essential hypertension, at doses of 75 mg, 150 mg and 300 mg alone, and in combination with hydrochlorothiazide (HCTZ)
- Trial name
- NCT00219024
- Testing
- aliskiren
- Where
- 2 sites in United States, Germany
- Volunteers
- 2,775 people
- Sponsor
- Novartis
Insufficient Sleep, Hypertension
Sleep Promotion and Pediatric Hypertension
Determine the effectiveness and feasibility of a mobile health sleep extension approach in the pediatric nephrology setting, to increase sleep duration and reduce systolic and diastolic blood pressure.
- Trial name
- NCT06642246
- Testing
- Intervention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Hypertension
LFF269 Compared to Placebo After Treatment in Subjects With Essential Hypertension
This study will assess the efficacy and safety of LFF269 compared to placebo after treatment in subjects with essential hypertension.
- Trial name
- NCT01373086
- Testing
- LFF269, Eplerenone
- Where
- 11 sites in United States
- Volunteers
- 19 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension,Essential
Pharmacological and Nonpharmacological Factors That Contribute Blood Pressure Control
Study is an observational study among hypertensive patients
- Trial name
- NCT05513430
- Volunteers
- 176 people
- Sponsor
- Maltepe University
Hypertension,Essential
Use of Metabolomics to Differentiate the Antihypertensive Effect of Acupuncture From Sham Acupuncture in Hypertensives
To assess the effect of acupuncture versus sham acupuncture on regulating the targeted metabolome of hypertensive patients.
- Trial name
- NCT03492892
- Testing
- Acupuncture
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Hypertension
Safety and Efficacy of Aliskiren 300 mg, 150 mg and 75 mg in Patients With Essential Hypertension Compared to Ramipril 5 mg
This study is designed to investigate the efficacy, safety and tolerability of aliskiren 300 mg, 150 mg and 75 mg when compared to ramipril 5 mg in patients with essential hypertension.
- Trial name
- NCT00529451
- Testing
- Aliskiren, Ramipril
- Where
- 3 sites in China, India and 1 more
- Volunteers
- 1,613 people
- Sponsor
- Novartis
Primary Hypertension
Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients
The Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) is a 2-arm, multi-center, prospective, randomized, open-labeled, blinded-endpoint trial.
- Trial name
- STEP (NCT03015311)
- Testing
- Intensive BP control, Standard BP control
- Where
- 42 sites in China
- Volunteers
- 8,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Primary Hypertension
Importance of Aldosterone in the Pathogenesis of Hypertensive Heart Disease
The Renin-Angiotensin-Aldosterone-system is important in the development of cardiovascular organ damage caused by arterial hypertension.
- Trial name
- NCT00865501
- Testing
- spironolactone
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Catecholamine; Overproduction, Catecholamine; Secretion
Sympathetic Activity and Cardiometabolic Complications
Recent studies on catecholamine physiology have shown a direct correlation with arterial hypertension, overcoming the exclusive role in the diagnosis and follow-up of chromaffin tumors.
- Conditions
- Catecholamine; Overproduction, Catecholamine; Secretion, Metabolic Syndrome, Hypertensive Heart Disease
- Trial name
- SYMPACT (NCT04495231)
- Where
- Italy
- Volunteers
- 1,380 people
- Sponsor
- University of Turin, Italy
Essential Hypertension, Chronic Stable Angina
Observational Study to Evaluate the Safety of DILATREND SR Cap. in Korean Patients With Essential Hypertension, Chronic Stable Angina and Congestive Heart Failure
The purpose of this study is to Evaluate the Safety of DILATREND SR Cap. in Korean Patients with Essential hypertension, Chronic stable angina and Congestive heart failure for 52 weeks.
- Conditions
- Essential Hypertension, Chronic Stable Angina, Congestive Heart Failure
- Trial name
- DELIGHT (NCT03063697)
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Essential Hypertension
Effect of DNS Exercises Training on Hypertension
Purpose of the study This study will be conducted to investigate any significant effect of dynamic neuromuscular stabilization training on postural control in patients with essential hypertension.
- Trial name
- NCT05900713
- Testing
- dynamic neuromuscular stabilization training, balance exercises plus diaphragmatic breathing
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Hypertension
A Clinical Study to Evaluate the Long-term Safety (12 Months) of the Combination of Aliskiren 300 mg and Hydrochlorothiazide 25 mg
The purpose of this study is to collect the long-term (12 months) safety data on aliskiren 300 mg when taken in combination with HCTZ 25 mg.
- Trial name
- NCT00171405
- Testing
- aliskiren
- Where
- 10 sites in United States, Belgium and 8 more
- Volunteers
- 250 people
- Sponsor
- Novartis
Hypertension, Stroke
A Blood Pressure Regulation and Stroke Risk Evaluation Study in Hypertensive Patients Treated With Eprosartan
The primary objective of the study is to evaluate the proportion of hypertensive patients who achieve regulation of their blood pressure (BP) levels according to the European Society of Cardiology / European School of Haematology…
- Trial name
- NCT01562613
- Where
- 84 sites in Greece
- Volunteers
- 533 people
- Sponsor
- Abbott
Hypertension,Essential, Prehypertension
The Antihypertensive Effect of Remote Ischemic Conditioning (RIC-HTN).
This study intends to further reveal the antihypertensive effect of LRIC and explore its potential mechanisms.
- Trial name
- NCT04915313
- Testing
- Remote ischemic conditioning (RIC)
- Where
- 3 sites in China
- Volunteers
- 95 people
- Sponsor
- Capital Medical University
Hypertension
Open-Label Long-Term Safety and Efficacy Study of Fixed Dose Combination of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Subjects With Moderate to Severe Essential Hypertension
This study examines the long term safety and efficacy of the Fixed Dose combination BAY98-7106 (nifedipine plus candesartan primarily at the highest dose in development) in patients with moderate to severe hypertension.
- Trial name
- NCT01788358
- Testing
- Nifedipine GITS/Candesartan Cilexetil FDC(BAY98-7106)
- Where
- 82 sites in United States, Belgium and 4 more
- Volunteers
- 508 people
- Sponsor
- Bayer
Hypertension,Essential
Licorice and Home Blood Pressure, Additional Study
Out-of-office blood pressure is more strongly associated with cardiovascular risk than office blood pressure. Licorice is known to raise blood pressure, but no previous studies have measured the effects on home blood pressure.
- Trial name
- NCT06019598
- Testing
- Licorice
- Where
- Sweden
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Hypertension
Pharmacodynamic Influences of Candesartan, Atenolol, Hydrochlorothiazide and Drug Combinations in Hypertensive Patients.
Angiotensin receptor antagonists (ARA), beta-blockers and diuretics do not seem to confer equivalent cardiovascular protection in hard outcomes clinical trials (beta blockers inferior).
- Trial name
- NCT00232882
- Testing
- Candesartan Thiazide, Atenolol Thiazide, Thiazide Candesartan
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Hypertension
Therapy of Essential Hypertension With Kinzal®/ Kinzalplus®
The efficacy and tolerability of an antihypertensive treatment with Telmisartan is followed over 3-4 months
- Trial name
- NCT00927537
- Testing
- Telmisartan (Kinzal/Pritor, BAY68-9291), Telmisartan (Kinzal/Pritor, BAY68-9291) + Hydrochlorothiazide
- Where
- Switzerland
- Volunteers
- 2,052 people
- Sponsor
- Bayer
Essential Hypertension
A Bioequivalence Study of L04TD3 Compared to Administration of L04RD1 in Healthy Volunteers
This is a randomized, open, single-dose, crossover-design, phase 1, singlecenter study to evaluate bioequivalence after administration of L04RD1 or administration of L04TD3 in healthy volunteers.
- Trial name
- NCT05993806
- Testing
- L04RD1, L04TD3
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Celltrion