Clinical trials: Essential Tremor, Movement Disorders
Essential Tremor
A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor
This multi-center, randomized, double-blinded, placebo-controlled, dose-range-finding clinical trial (with an optional Extension comprised of an Extension Double-blind (DB) Lead in Period followed by an Extension Open-label (OL)…
- Trial name
- Essential1 (NCT05021991)
- Testing
- 100 mg PRAX-944, 60 mg PRAX-944, Flexibly dosed 20 mg to 100 mg PRAX-944
- Where
- 39 sites in United States, Canada
- Volunteers
- 133 people
- Sponsor
- Praxis Precision Medicines
Parkinson Disease, Essential Tremor
Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation
Individuals experiencing tremors face difficulty performing activities of daily living caused by involuntary oscillation of the muscles in the hands and arms.
- Trial name
- Tremor (NCT05308368)
- Testing
- Ultrasound Imaging, Electromyography, Inertial Measurement Units (IMU)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Essential Tremor
Multiple-dose,Double-blind,Placebo-controlled Study of Sodium Oxybate in Patients With Essential Tremor
To determine the relationship between drug plasma levels and safety, tolerability and efficacy in patients with essential tremors after dosing with Sodium oxybate
- Trial name
- NCT00598078
- Testing
- Sodium Oxybate
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Jazz Pharmaceuticals
Essential Tremor, Upper Extremity Essential Tremor
Coordinated Reset Deep Brain Stimulation for Essential Tremor
Deep brain stimulation (DBS) is a surgical procedure for the treatment of Essential Tremor (ET). A novel approach to current DBS approaches is called coordinated reset DBS (CR-DBS) which uses different patterns of stimulation at…
- Trial name
- NCT05897775
- Testing
- Deep brain stimulation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Minnesota
Parkinson's Disease, Essential Tremor
Optimizing DBS Electrode Placement and Programming
Deep brain stimulation (DBS) has become the primary surgical therapy for the treatment of motor symptoms associated with Parkinson's disease (PD), and for essential tremor (ET).
- Trial name
- NCT01820390
- Where
- 2 sites in United States
- Sponsor
- University of Colorado, Denver
Essential Tremor, Deep Brain Stimulation
Probabilistic Targeting of the VIM
After having included the most improved patients by DBS among those implanted in Bordeaux Hospital University, and having defined the most active plots on tremor by its prospective grading on Fahn-Tolosa-Marin (FTM) scale and…
- Trial name
- PROBA-VIM (NCT03696420)
- Testing
- Coordinates of active plots and VIM landmarks calculation
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Bordeaux
Essential Tremor
A Clinical Trial of PRAX-114 in Participants With Essential Tremor
This is a 2-part clinical trial to evaluate the safety, tolerability, pharmacokinetics, and efficacy of PRAX-114 in participants with essential tremor (ET).
- Trial name
- NCT05387642
- Testing
- 10 mg PRAX-114 or 20 mg PRAX-114
- Where
- 3 sites in United States
- Sponsor
- Praxis Precision Medicines
Essential Tremor
Chinese ET Registry (CETR)
The purpose of the Chinese Essential Tremor Registry (CETR) is to develop a database of patients with Essential tremor in China.
- Trial name
- NCT04198246
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xiangya Hospital of Central South University
Essential Tremor
Assessment of the Safety and Efficacy of the Felix NeuroAI Wristband in Essential Tremor
The goal of this clinical study is to compare Felix NeuroAI Wristband and sham device in patients with essential tremor. The main question it aims to answer is: Is Felix a safe and efficacious treatment for patients with…
- Trial name
- TRANQUIL (NCT06235190)
- Testing
- Felix NeuroAI Wristband
- Where
- 12 sites in United States, China
- Volunteers
- 125 people
- Sponsor
- Fasikl Inc.