Clinical trials: Esthetic
Black Triangles Syndrome (BTS), Periodontal Gingival Contraction
Evaluation of the Safety and Performance of the Medical Device RDM36 in the Treatment of Periodontal Gingival Contraction and in Black Triangles Syndrome (BTS)
The treatment of black triangles in modern dentistry involves various approaches, both surgical and nonsurgical. Surgical methods aim to reconstruct or preserve gingival tissue using techniques such as soft tissue flaps or…
- Trial name
- NCT07185191
- Testing
- RDM36, Saline Solution (NaCl 0,9%)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Mastelli S.r.l
Bilateral Breast Augmentation
Evaluation of the Safety and Performance of SYMATESE AESTHETICS ESTYME® MATRIX Round Microtextured Silicone Gel-Filled Breast Implants in the Breast Augmentation
The purpose of this study is to collect clinical data to evaluate the safety and performance of ESTYME® MATRIX Round microtextured breast implants in patients who receive these silicone gel-filled implants as part of their breast…
- Trial name
- EMMA (NCT05336526)
- Testing
- ESTYME® MATRIX Round Microtextured Silicone Gel-Filled Breast Implants
- Where
- 6 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Symatese Aesthetics
Aesthetics Procedure
Post-market Study on BtHCROSS® for Restoring Facial Volume After a Single Injection
This clinical study investigated the safety and effectiveness of BtHCROSS, a hyaluronic acid-based injectable used to restore facial volume and reduce wrinkles.
- Trial name
- NCT07301619
- Testing
- BtHCROSS®
- Where
- Spain
- Volunteers
- 203 people
- Sponsor
- i+Med S.Coop.
Skin Hydration, Skin Elasticity
Efficacy and Safety of PN+HA (NEWEST) for the Improvement of Skin Hydration
This is a post-market, monocentric, interventional, single-arm, confirmative clinical investigation to evaluate the performance and the safety of PN+HA (NEWEST) for the improvement of skin hydration.
- Trial name
- NCT06821867
- Testing
- PN + HA (Newest)
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mastelli S.r.l
Aesthetics, Intradermal Injections
Clinical Evaluation of the Safety and Performance of a Filler in Correction of Mid-face Age-related Volume Deficit
Prospective, single center study, on healthy subjects to evaluate the aesthetic improvement of facial volume, effect on the restoration and/or augmentation in subjects with mid-face age-related volume deficit after injection of a…
- Trial name
- NCT04505319
- Testing
- DEFINISSE CORE FILLER
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Relife S.r.l.
Muscle Tightness
Non-invasive Buttock Lifting Induced by Magnetic Device - Multicentric Study
This study will evaluate the clinical safety and patient satisfaction with the high power magnet system for the aesthetic improvement of buttocks. The study is a prospective multi-center open-label single-arm study.
- Trial name
- NCT03579147
- Testing
- Treatment with BTL EMSCULPT device
- Where
- 7 sites in United States, Bulgaria
- Volunteers
- healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Acne Scars
Evaluation of Juläine (TM) for the Treatment of Atrophic Facial Acne Scars
This study aims to evaluate the effectiveness and safety of Juläine, an injectable medical device made of polylactic acid, for treating facial acne scars.
- Trial name
- NCT07058883
- Testing
- Juläine
- Where
- 2 sites in Poland
- Volunteers
- 55 people
- Sponsor
- Nordberg Medical AB
Glabellar Frown Lines, Canthal Lines
Assess Aesthetic Improvement With QM1114-DP in Subjects With Moderate to Severe Lateral Canthal Lines and Glabellar Lines
This study to assess aesthetic improvement following treatment with QM1114-DP.
- Trial name
- NCT05148000
- Testing
- QM1114-DP
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Idiopathic Scoliosis
Scoliosis Surgery Using the PASS® LP System
The purpose of this study is to find out the outcomes of using the PASS LP System to correct idiopathic scoliosis. This system is a unique set of spinal instrumentation used to surgically correct the rotation and deformity of the…
- Trial name
- NCT01019109
- Testing
- Posterior Spinal Fusion Device: Titanium rod arm used titanium rods, and CoCr rod arm used Cobalt Chrome rods as a part of the construct.
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Medicrea, USA Corp.
Aging, Aesthetic
Clinical Performance and Safety of STYLAGE® HydroMax
FHAME is a post-market clinical investigation designed to strengthen the clinical evidence supporting the effectiveness of STYLAGE® HydroMax in the treatment of superficial wrinkles, primarily on the cheeks.
- Trial name
- FHAME (NCT07153237)
- Testing
- STYLAGE® HydroMax
- Where
- 2 sites in France
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Facial Wrinkles, Skin Aging
Evaluation of MD60002 Device for Facial Skin Aging
This single-center, non-controlled, single-arm clinical study is designed to evaluate the performance and safety of the Class III investigational device MD60002 (composed of highly purified polynucleotides at 3%) for aesthetic…
- Conditions
- Facial Wrinkles, Skin Aging, Skin Imperfections
- Trial name
- CIP-02-25 (NCT07881926)
- Testing
- Device: MD60002
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Promoitalia Group Spa
Cheek, Wrinkle
Open Label Extension for 43USSA1812
To evaluate long-term safety and effectiveness data of Sculptra Aesthetic beyond the Month 12 duration of the pivotal study 43USSA1812 (NCT04124692) to help characterize the long-term safety and effectiveness profile of the more…
- Trial name
- NCT04595331
- Testing
- Sculptra Aethestic reconsituted with 8ml Sterile Water for Injection
- Where
- 13 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Nasolabial Folds
Juvederm Ultra With Lidocaine Compared With Restylane for the Correction of Nasolabial Folds
Comparison of the safety and effectiveness of Juvederm Ultra with lidocaine compared with Restylane in the correction of nasolabial folds.
- Trial name
- NCT00850889
- Testing
- Hyaluronic acid gel (24 mg/mL) with 0.3% lidocaine, A gel of hyaluronic acid (concentration of 20 mg/mL)
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Allergan Medical
Breast Implant
Motiva Implants® Post-Approval Study
This study examines the general post-market use and safety of Motiva Implants® and gathers and assesses selected safety and effectiveness data about their post market performance and experience.
- Trial name
- Motiva PAS (NCT06938399)
- Testing
- Silicone gel-filled breast implants - Motiva Implants®, Aesthetic Surgery
- Where
- 33 sites in United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Motiva USA LLC
Glabellar Lines
Long-Term Patient Satisfaction of Facial Aesthetic Treatment With BOTOX®
This is an observational study assessing patient satisfaction following at least 5 years of BOTOX® treatment for glabellar lines.
- Trial name
- NCT01608672
- Testing
- botulinum toxin Type A
- Where
- 5 sites in United States, Australia and 3 more
- Volunteers
- 207 people
- Sponsor
- Allergan
Nasolabial Folds
Dermal Evaluation of Facetem™ S in Nasolabial Folds Esthetics Improvement: DEFINE Study
This is a multicenter, prospective, non-randomized, uncontrolled post-market clinical follow-up (PMCF) study designed to evaluate the performance and safety of Facetem S dermal filler for the correction of moderate-to-severe…
- Trial name
- DEFINE (NCT07855224)
- Testing
- Facetem S
- Where
- 5 sites in France, Spain
- Volunteers
- 100 people
- Sponsor
- CGBio Inc.
Aesthetic Correction of the Lips
Clinical Investigation on Lips Treated With HA-filler
A post-market-clinical follow-up investigation to confirm the clinical safety and performance profile of Decoria® Essence for the correction and improvement of lips profile.
- Trial name
- DAG-ESS (NCT07188818)
- Testing
- Decoria Essence
- Where
- 6 sites in Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bohus Biotech AB
Aesthetics
Safety and Efficacy of Azzalure/Dysport, Restylane/Emervel Filler and Restylane Skinbooster Treatment
The efficacy and safety, as well as subject satisfaction will be evaluated after single treatment with Azzalure/Dysport alone or Restylane/Emervel filler alone followed by repeated combined treatment with Azzalure/Dysport…
- Trial name
- NCT02297516
- Testing
- Azzalure or Dysport, Restylane or Emervel filler, Restylane Skinbooster
- Where
- 4 sites in Brazil, France and 1 more
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Esthetics
Effectiveness and Safety of STYLAGE® M Lidocaïne for Lips' Volume Augmentation and/or Redefinition of the Outline of the Lips (SMILE)
STYLAGE® M Lidocaine is a hyaluronic acid injectable gel CE (conformité européenne)-marketed since 2009 . It is indicated for the outline of the lips and/or for lips augmentation in lips mucosa.
- Trial name
- SMILE (NCT04813614)
- Testing
- STYLAGE M Lidocaine, Active control group
- Where
- 2 sites in France, Poland
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Post-Mastectomy Breast Deformity (Disorder)
Investigate Wound Healing, Aesthetics & Pt Satisfaction Post NAC Reconstruction Using a Decellularized Donor NAC Graft
To evaluate the wound healing response following nipple-areolar complex (NAC) reconstruction with a decellularized donor NAC graft (DCLNAC)
- Trial name
- NCT05484934
- Testing
- Regenerative post mastectomy surgery
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- BioAesthetics