Clinical trials: Esthetic
Appearance of Facial Wrinkles, Aesthetic
Evaluation of a Non-cross-linked Hyaluronic Acid Medical Device ("Electri" and "XELA REDERM") for Improving Facial Skin Appearance
The goal of this clinical investigation is to learn whether injectable implants based on non-cross-linked hyaluronic acid (Electri and XELA REDERM) improve the aesthetic appearance of facial skin in adult women.
- Conditions
- Appearance of Facial Wrinkles, Aesthetic, Hydration, Facial Skin Wrinkles
- Trial name
- RegHyal-01 (NCT06984432)
- Testing
- XELA REDERM (non-cross-linked hyaluronic acid 1.1%, 1.8%, or 2.2%), Electri (non-cross-linked hyaluronic acid 0.55%)
- Where
- 4 sites in Poland, Ukraine
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Institute Hyalual GmbH
Chemotherapy Effect
Anxiolytic Effects of Socio-aesthetics in Cancer Patients Undergoing Chemotherapy
The purpose of the study is to assess the average of the "State Anxiety" score of the State Trait Inventory Anxiety at the end of the third cycle of chemotherapy compared to the pre-treatment score (inclusion)
- Trial name
- PASITHEA (NCT05649852)
- Testing
- Socio-aesthetic care, Supportive care
- Where
- France
- Volunteers
- 192 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Dental Implants, Single-tooth, Crown
Immediate Loading of Implants in the Aesthetic Zone Using Three-dimensionally Printed Provisional Crowns: a 1-year Prospective Case Series Study
Background There is a growing tendency to place a provisional crown immediately following implant placement. Clinical advantages are shortening of treatment duration and soft tissue guiding during healing resulting in better…
- Trial name
- NCT07629752
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Skin Hydration, Skin Elasticity
Efficacy and Safety of PN+HA (NEWEST) for the Improvement of Skin Hydration
This is a post-market, monocentric, interventional, single-arm, confirmative clinical investigation to evaluate the performance and the safety of PN+HA (NEWEST) for the improvement of skin hydration.
- Trial name
- NCT06821867
- Testing
- PN + HA (Newest)
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mastelli S.r.l
Teeth Absent, Teeth Missing
Multicenter Clinical Study on the Efficacy and Esthetic Outcomes of Immediate Implant Placement Using the Socket-Shield Technique Versus Conventional Immediate Implantation in the Anterior Maxillary Esthetic Zone
This study plans to enroll no fewer than 48 adult patients who have non-restorable maxillary anterior teeth due to trauma or dental diseases and are candidates for immediate implant placement, meeting the inclusion and exclusion…
- Conditions
- Teeth Absent, Teeth Missing, Dental Implant
- Trial name
- NCT07822685
- Testing
- the Socket Shield Technique (SST) immediate implant placement, Conventional immediate implant placement
- Volunteers
- 48 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Cutaneous Surgery
Aesthetic Outcome of Electrodesiccation and Curettage vs Excision With Complex Linear Closure
The purpose of this study is to determine whether electrodesiccation and curettage (ED\&C) versus excision with complex linear closure affects esthetic outcomes (primary outcome).
- Trial name
- NCT05074225
- Testing
- Electrodesiccation and Curettage vs Excision
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of California, Davis
Pain, Complications
Evaluation of Satisfaction in Patients Undergoing Non Surgical Lifting by Means of Coned Wires.
An email questionnaire about subjective satisfaction and discomfort has been sent to 243 patients undergoing non-surgical facial and cervical lift 1 week, 1 month, 6 months and 1 year after treatment.
- Trial name
- SCW (NCT02347826)
- Where
- Italy
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- AQ-DE
Smile, Smile Esthetics
Validation of the French Version of the SERQoL Questionnaire
This observational study aims to validate the French version of the Smile Esthetics-Related Quality of Life (SERQoL) questionnaire in adult patients recruited in two APH-HP dental departments.
- Trial name
- Periosmile1 (NCT07372105)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Patients in Need of Surgical CL in the Anterior Maxillary Sextant for Restorative Purposes
One- Versus Two-Stage Aesthetic Crown Lengthening
This randomized controlled trial was aimed at assessing the efficacy of a two-stage crown lengthening intervention (SCL) for restorative purposes in the aesthetic zone compared with a one-stage crown lengthening procedure (CCL).
- Trial name
- NCT04409366
- Testing
- Conventional Crown Lengthening (CCL), Two-stage Crown Lengthening (SCL)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Implant Placement in Maxillary Esthetic Zone, Immediate Dental Implant Loading
Vertical Root Extraction for Immediate Implant
Immediate implant placement in the esthetic zone has become a preferred treatment modality due to its potential to shorten treatment duration, reduce surgical interventions, and preserve the natural contour of peri-implant…
- Trial name
- Benex (NCT07374627)
- Testing
- vertical extraction, Conventional exctraction
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lip, Prosthesis User
Facial Scanning for Lip Support Assessment in Full Arch Implant Rehabilitations
Lip support plays an important role in facial esthetics, being a relevant factor when realizing full arch implant supported rehabilitations.
- Conditions
- Lip, Prosthesis User, Soft Tissue
- Trial name
- NCT04753866
- Testing
- Facial scanner
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Lipodystrophies, Aesthetics Procedure
Safety Study of Filler Agent Composed of Autologous Mesenchymal Stem Cells and Hyaluronic Acid
Lipodystrophies are part of a clinically heterogeneous group of disorders characterized by loss (lipoatrophies) and / or accumulation of fat, which usually results in a change of normal tissue surface.
- Trial name
- LipAge (NCT02034786)
- Testing
- Adipose tissue collection, Transdermal injection
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cryopraxis Criobiologia Ltda.
Esthetic Zone
Efficacy of i-PRF Usage in Vestibular Socket Therapy
This study aims for evaluation of A novel method for evaluating i-PRF usage in vestibular socket therapy for immediate implant in defective fresh extraction site.
- Trial name
- NCT07304986
- Testing
- Immediate implant with VST, Immediate implant with VST and i-prf
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Skin Aging, Skin Condition
A Clinical Study on Pre-operative Intervention With Products During Aesthetic Medicine
This clinical trial aims to evaluate whether a 14-day pre-operative application of the test product (containing MLYAAT-1002®, a proprietary anti-aging complex) can mitigate skin discomfort during Fotona 4D laser therapy (Frac3…
- Conditions
- Skin Aging, Skin Condition, Skin Manifestations
- Trial name
- NCT06891924
- Testing
- 14-day daily pre-operative application of the formulations containing MLYAAT-1002® before Fotona4D treatment, 14-day daily pre-operative application of the formulations without MLYAAT-1002® before Fotona4D treatment
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Botanee Group Co., Ltd.
Lower Lip Tissue Loss, Cancer
Functional and Aesthetic Outcomes Following Lower Lip Reconstruction
This retrospective study, aims to evaluate the functional and aesthetic results of lower lip reconstructions, incorporating both patient experiences and the analysis of physicians and surgeons working on facial issues (plastic…
- Trial name
- REFEPLI (NCT07298070)
- Testing
- Patient-Reported Outcome Questionnaire (post-operative)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hôpital NOVO
Dental Disorders Hard Tissues of Teeth, Tooth Discoloration
Effect of Preparation Design on the Functional and Esthetic Outcome of CAD/CAM Lithium Disilicate Laminate Veneers
Conservatism is considered the main concern in any treatment plan, the feather edge preparation design of laminate veneers have been introduced yet clinical studies are lacking to evaluate their clinical performance.The aim of…
- Trial name
- NCT04840524
- Testing
- Laminate veneers preparation
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cancer of Colon, Cancer, Lung
Evaluation of the Medical Service by Socio-aesthetics in Oncology
the 3-year randomized controlled RCT-SE study aims to investigate Socio-aesthetics well being care on quality of life, pain and anxiety.
- Conditions
- Cancer of Colon, Cancer, Lung, Cancer, Breast, Cancer Prostate
- Trial name
- RCT-SE (NCT06035731)
- Testing
- SOCIO-AESTHETICS care
- Where
- 3 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier de Valence
Cheek, Wrinkle
Open Label Extension for 43USSA1812
To evaluate long-term safety and effectiveness data of Sculptra Aesthetic beyond the Month 12 duration of the pivotal study 43USSA1812 (NCT04124692) to help characterize the long-term safety and effectiveness profile of the more…
- Trial name
- NCT04595331
- Testing
- Sculptra Aethestic reconsituted with 8ml Sterile Water for Injection
- Where
- 13 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Alveolar Socket Preservation
Evaluation of Bone Changes After Immediate Implant Placement or Socket Preservation With or Without Surgical Flap in The Aesthetic Zone
The amount of hard tissue resorption following tooth extraction involves prosthetically driven implant placement; therefore, the development of ridge preservation techniques that result in less alveolar bone loss is of great…
- Trial name
- NCT03690973
- Testing
- Alveolar socket preservation with graft and flap surgery, Immediate implant placement with bone using flapless surgery, Immediate implant placement with bone using flap surgery
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Implants
Association of Implant Position and Crown Contour With Tissue Health
Emergence profile and crown contour of implant supported rehabilitation, which is influenced by implant position, is associated with peri-implant health and esthetic outcomes.
- Trial name
- NCT05644470
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University